Abstract
In the present study, the concentrations of Co, Cr, Fe, Hg, Rb, Se, Zn in the serum of 103 adult patients with newly diagnosed of leukemia (before treatment) were studied. Samples were collected from Radiation of Isotopes Center-Khartoum (RICK) and Institute of Nuclear Medicine and Molecular Biology-Aljazeera State. Samples were freeze-dried and analyzed using Neutron Activation Analysis (NAA). Serum levels of these elements were compared with the contents found in healthy group samples. The patients were divided into 4 groups: 1- Acute Lymphoid Leukemia (ALL), 2- Acute Myeloid Leukemia (AML), 3- Chronic Lymphoid Leukemia (CLL), 4- Chronic Myeloid Leukemia (CML). The control group was formed of 40 healthy subjects, data analysis was performed using the T-tests. partial correlation was used to study a relationship between two variables. It was found that, In group I (ALL): higher concentration of Cr, Fe, Hg, Rb, Zn, were found in the serum of patients with significant difference as compared to healthy group (p < 0.05). The concentration of Co was higher than the control group but statistically not significant. The level of selenium was considerably lower than in the control group (p < 0.05). In group II (AML): Significantly elevated values were found in
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Elradi, M M. M.
[1]
- Atomic Energy Council, Sudan Academy of Sciences, Khartoum (Sudan)
Citation Formats
Elradi, M M. M.
Investigation of selected trace elements in Sudanese patients with leukemia using NAA.
Sudan: N. p.,
2010.
Web.
Elradi, M M. M.
Investigation of selected trace elements in Sudanese patients with leukemia using NAA.
Sudan.
Elradi, M M. M.
2010.
"Investigation of selected trace elements in Sudanese patients with leukemia using NAA."
Sudan.
@misc{etde_21496825,
title = {Investigation of selected trace elements in Sudanese patients with leukemia using NAA}
author = {Elradi, M M. M.}
abstractNote = {In the present study, the concentrations of Co, Cr, Fe, Hg, Rb, Se, Zn in the serum of 103 adult patients with newly diagnosed of leukemia (before treatment) were studied. Samples were collected from Radiation of Isotopes Center-Khartoum (RICK) and Institute of Nuclear Medicine and Molecular Biology-Aljazeera State. Samples were freeze-dried and analyzed using Neutron Activation Analysis (NAA). Serum levels of these elements were compared with the contents found in healthy group samples. The patients were divided into 4 groups: 1- Acute Lymphoid Leukemia (ALL), 2- Acute Myeloid Leukemia (AML), 3- Chronic Lymphoid Leukemia (CLL), 4- Chronic Myeloid Leukemia (CML). The control group was formed of 40 healthy subjects, data analysis was performed using the T-tests. partial correlation was used to study a relationship between two variables. It was found that, In group I (ALL): higher concentration of Cr, Fe, Hg, Rb, Zn, were found in the serum of patients with significant difference as compared to healthy group (p < 0.05). The concentration of Co was higher than the control group but statistically not significant. The level of selenium was considerably lower than in the control group (p < 0.05). In group II (AML): Significantly elevated values were found in Cr and Fe as compared to the control group. The concentrations of Co, Hg and Zn also were higher but statistically not significant (p> 0.05), the level of selenium was statistically lower than in the control group (p< 0.05). In group III (CLL): It was observed that contents of the Cr, Fe, Hg, Rb, Zn elements were elevated significantly (p<0.05) than healthy subjects. The concentration of Co was higher than the control group but statistically not significant, the level of selenium was considerably lower than in the control group (p < 0.05). In group 4 (CML): The concentrations of Fe, Hg, Rb, Zn were statistically higher than in the healthy subject (p < 0.05). Also the level of Cr was higher but statistically not significant (p> 0.05). Similar result was obtained in Co. The level of selenium was statistically lower than in the control group (p< 0.05). (Author)}
place = {Sudan}
year = {2010}
month = {Oct}
}
title = {Investigation of selected trace elements in Sudanese patients with leukemia using NAA}
author = {Elradi, M M. M.}
abstractNote = {In the present study, the concentrations of Co, Cr, Fe, Hg, Rb, Se, Zn in the serum of 103 adult patients with newly diagnosed of leukemia (before treatment) were studied. Samples were collected from Radiation of Isotopes Center-Khartoum (RICK) and Institute of Nuclear Medicine and Molecular Biology-Aljazeera State. Samples were freeze-dried and analyzed using Neutron Activation Analysis (NAA). Serum levels of these elements were compared with the contents found in healthy group samples. The patients were divided into 4 groups: 1- Acute Lymphoid Leukemia (ALL), 2- Acute Myeloid Leukemia (AML), 3- Chronic Lymphoid Leukemia (CLL), 4- Chronic Myeloid Leukemia (CML). The control group was formed of 40 healthy subjects, data analysis was performed using the T-tests. partial correlation was used to study a relationship between two variables. It was found that, In group I (ALL): higher concentration of Cr, Fe, Hg, Rb, Zn, were found in the serum of patients with significant difference as compared to healthy group (p < 0.05). The concentration of Co was higher than the control group but statistically not significant. The level of selenium was considerably lower than in the control group (p < 0.05). In group II (AML): Significantly elevated values were found in Cr and Fe as compared to the control group. The concentrations of Co, Hg and Zn also were higher but statistically not significant (p> 0.05), the level of selenium was statistically lower than in the control group (p< 0.05). In group III (CLL): It was observed that contents of the Cr, Fe, Hg, Rb, Zn elements were elevated significantly (p<0.05) than healthy subjects. The concentration of Co was higher than the control group but statistically not significant, the level of selenium was considerably lower than in the control group (p < 0.05). In group 4 (CML): The concentrations of Fe, Hg, Rb, Zn were statistically higher than in the healthy subject (p < 0.05). Also the level of Cr was higher but statistically not significant (p> 0.05). Similar result was obtained in Co. The level of selenium was statistically lower than in the control group (p< 0.05). (Author)}
place = {Sudan}
year = {2010}
month = {Oct}
}