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An experimental study on effect of radiation in palate development of rat embryo

Journal Article:

Abstract

The author observed morphological change in palate development of rat embryo after irradiation of x-ray on the one side of the duplex uterus. The time matings occurred between 6 p.m. and 8 a.m. and all female with copulation plugs at 8 a.m. were isolated and properly marked for evidence of copulation. The lower left abdomen of mothers were exposed to x-radiation on the 7 1/2th, 9 1/2th, 11 1/2th day of gestation, respectively 150, 250, 350, 500 rads. At 18 1/2th day of post-conception, the pregnant female were dissected and the contents of the two uteri examined. The translucent sample by Alizarin red S stain were prepared. The results were as follows; 1. The result that groups irradiated by 250 rads and 350 rads made marked difference in comparison with the control group suggests the x-ray to be an inducing factor of cleft palate. 2. At 11 1/2th day of gestation, incidence of cleft palate induced by x-irradiation was highest. 3. Mortality showed the highest frequency at 7 1/2th day of gestation, and tended to decrease according to increasing of age. 4. Morphology of cleft palate induced by x-irradiation showed similarity in comparison with those induced by other factors having  More>>
Authors:
Khim, Jhai Duck; You, Dong Soo [1] 
  1. Department of Dental Radiology, Graduate School, Seoul National University, Seoul (Korea, Republic of)
Publication Date:
Nov 15, 1976
Product Type:
Journal Article
Resource Relation:
Journal Name: Korean Journal of Oral and Maxillofacial Radiology; Journal Volume: 6; Journal Issue: 1
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; EMBRYOS; MORPHOLOGICAL CHANGES; RADIATIONS; RATS; UTERUS; ANIMALS; BODY; FEMALE GENITALS; MAMMALS; ORGANS; RODENTS; VERTEBRATES
OSTI ID:
21482179
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 1229-8212; TRN: KR1102446074779
Submitting Site:
KRN
Size:
page(s) 45-50
Announcement Date:
Sep 29, 2011

Journal Article:

Citation Formats

Khim, Jhai Duck, and You, Dong Soo. An experimental study on effect of radiation in palate development of rat embryo. Korea, Republic of: N. p., 1976. Web.
Khim, Jhai Duck, & You, Dong Soo. An experimental study on effect of radiation in palate development of rat embryo. Korea, Republic of.
Khim, Jhai Duck, and You, Dong Soo. 1976. "An experimental study on effect of radiation in palate development of rat embryo." Korea, Republic of.
@misc{etde_21482179,
title = {An experimental study on effect of radiation in palate development of rat embryo}
author = {Khim, Jhai Duck, and You, Dong Soo}
abstractNote = {The author observed morphological change in palate development of rat embryo after irradiation of x-ray on the one side of the duplex uterus. The time matings occurred between 6 p.m. and 8 a.m. and all female with copulation plugs at 8 a.m. were isolated and properly marked for evidence of copulation. The lower left abdomen of mothers were exposed to x-radiation on the 7 1/2th, 9 1/2th, 11 1/2th day of gestation, respectively 150, 250, 350, 500 rads. At 18 1/2th day of post-conception, the pregnant female were dissected and the contents of the two uteri examined. The translucent sample by Alizarin red S stain were prepared. The results were as follows; 1. The result that groups irradiated by 250 rads and 350 rads made marked difference in comparison with the control group suggests the x-ray to be an inducing factor of cleft palate. 2. At 11 1/2th day of gestation, incidence of cleft palate induced by x-irradiation was highest. 3. Mortality showed the highest frequency at 7 1/2th day of gestation, and tended to decrease according to increasing of age. 4. Morphology of cleft palate induced by x-irradiation showed similarity in comparison with those induced by other factors having been reported ever.}
journal = {Korean Journal of Oral and Maxillofacial Radiology}
issue = {1}
volume = {6}
place = {Korea, Republic of}
year = {1976}
month = {Nov}
}