You need JavaScript to view this

Assessment of laryngeal functions in patients with squamous cell carcinoma of the larynx or hypopharynx treated with concurrent chemoradiotherapy

Abstract

The laryngeal functions in patients with laryngeal or hypopharyngeal cancer treated with concurrent chemoradiotherapy (CCRT) were evaluated. We reviewed the records of 32 patients with resectable stage II to IV squamous cell carcinoma of the larynx or hypopharynx treated with CCRT as a initial treatment between October 1998 and September 2003. A questionnaire survey and measurements of maximum phonation time, GRBAS and range of voice/speaking fundamental frequency were performed, and the method of food intake in the swallowing ability scale and the presence of tracheostoma were assessed for evaluating laryngeal functions after CCRT. After CCRT for laryngeal or hypopharyngeal cancer, the phonatory functions appeared to be preserved in 75% of the patients in terms of sustainability; however, there were some cases presenting hoarseness and narrowed range of voice. Oral intake was possible in most cases (97%) without a history of aspiration pneumonia. In 2 cases, permanent tracheostoma had to be retained. It was concluded that laryngeal functions could be preserved in most cases after CCRT, though the tracheostoma might not be closed in some patients with laryngeal cancer. (author)
Authors:
Taguchi, Takahide; Tsukuda, Mamoru; Nagao, Jun-ichi [1] 
  1. Yokohama City Univ., School of Medicine, Yokohama, Kanagawa (Japan)
Publication Date:
Dec 15, 2010
Product Type:
Journal Article
Resource Relation:
Journal Name: Nippon Kikan Shokudoka Gakkai Kaiho; Journal Volume: 61; Journal Issue: 6
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BIOLOGICAL FUNCTIONS; CARCINOMAS; CHEMOTHERAPY; COMBINED THERAPY; FEEDING; FRACTIONATED IRRADIATION; INSPECTION; LARYNX; PATIENTS; PHARYNX; RADIATION DOSES; RADIOTHERAPY; BODY; DIGESTIVE SYSTEM; DISEASES; DOSES; IRRADIATION; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY
OSTI ID:
21469963
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: ISSN 0029-0645; TRN: JP1102082063215
Submitting Site:
INIS
Size:
page(s) 483-492
Announcement Date:
Aug 18, 2011

Citation Formats

Taguchi, Takahide, Tsukuda, Mamoru, and Nagao, Jun-ichi. Assessment of laryngeal functions in patients with squamous cell carcinoma of the larynx or hypopharynx treated with concurrent chemoradiotherapy. Japan: N. p., 2010. Web. doi:10.2468/jbes.61.483.
Taguchi, Takahide, Tsukuda, Mamoru, & Nagao, Jun-ichi. Assessment of laryngeal functions in patients with squamous cell carcinoma of the larynx or hypopharynx treated with concurrent chemoradiotherapy. Japan. https://doi.org/10.2468/jbes.61.483
Taguchi, Takahide, Tsukuda, Mamoru, and Nagao, Jun-ichi. 2010. "Assessment of laryngeal functions in patients with squamous cell carcinoma of the larynx or hypopharynx treated with concurrent chemoradiotherapy." Japan. https://doi.org/10.2468/jbes.61.483.
@misc{etde_21469963,
title = {Assessment of laryngeal functions in patients with squamous cell carcinoma of the larynx or hypopharynx treated with concurrent chemoradiotherapy}
author = {Taguchi, Takahide, Tsukuda, Mamoru, and Nagao, Jun-ichi}
abstractNote = {The laryngeal functions in patients with laryngeal or hypopharyngeal cancer treated with concurrent chemoradiotherapy (CCRT) were evaluated. We reviewed the records of 32 patients with resectable stage II to IV squamous cell carcinoma of the larynx or hypopharynx treated with CCRT as a initial treatment between October 1998 and September 2003. A questionnaire survey and measurements of maximum phonation time, GRBAS and range of voice/speaking fundamental frequency were performed, and the method of food intake in the swallowing ability scale and the presence of tracheostoma were assessed for evaluating laryngeal functions after CCRT. After CCRT for laryngeal or hypopharyngeal cancer, the phonatory functions appeared to be preserved in 75% of the patients in terms of sustainability; however, there were some cases presenting hoarseness and narrowed range of voice. Oral intake was possible in most cases (97%) without a history of aspiration pneumonia. In 2 cases, permanent tracheostoma had to be retained. It was concluded that laryngeal functions could be preserved in most cases after CCRT, though the tracheostoma might not be closed in some patients with laryngeal cancer. (author)}
doi = {10.2468/jbes.61.483}
journal = []
issue = {6}
volume = {61}
place = {Japan}
year = {2010}
month = {Dec}
}