You need JavaScript to view this

Investigation of selected trace elements in hair samples of eczema patients

Abstract

The aim of this case-control study was to investigate the relationship between selected trace elements and skin diseases, namely eczema. Fifty five patients affected by the most frequent eczema types were recruited at the onset of disease at the hospital of dermatology in Khartoum together with thirty healthy controls. Fe, Zn, Cu, and Ni were measured in hair samples obtained from both patients and control group using Atomic Absorption Spectrometry (AAS). Data analysis was performed using the T-test. Partial correlation was used to study the relationship between the elemental concentration. Certified reference material (IAEA-85) Hair Powder) produced by the International Atomic Energy Agency (IAEA) was used as a quality control to check the accuracy and precision of the analytical technique, good agreement was achieved for all elements under investigation. Significant variations (p<0.05) in the concentrations of Fe, Zn, Cu, and Ni in the hair of the patients compared to the control group, and this difference was a decrease of iron, zinc and copper, therefore, should be given to the patient doses of these elements, while there was an increase in the nickel. So it is not included in the treatment. These interesting associations between the levels the of trace elements  More>>
Authors:
Osman, N O [1] 
  1. Atomic Energy Council, Sudan Academy of Sciences (SAS), Khartoum (Sudan)
Publication Date:
Dec 15, 2010
Product Type:
Thesis/Dissertation
Report Number:
INIS-SD-407
Resource Relation:
Other Information: TH: Thesis (M.Sc.); 61 refs.; 17 figs.; 8 tabs.
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; ABSORPTION SPECTROSCOPY; CONCENTRATION RATIO; DOSES; ECZEMA; HAIR; IRON; LEVELS; NICKEL; NUMERICAL DATA; PATIENTS; SKIN DISEASES; SUDAN; TRACE AMOUNTS; ZINC; AFRICA; ARAB COUNTRIES; BODY; DATA; DEVELOPING COUNTRIES; DIMENSIONLESS NUMBERS; DISEASES; ELEMENTS; INFORMATION; METALS; ORGANS; SKIN; SPECTROSCOPY; TRANSITION ELEMENTS
OSTI ID:
21468025
Research Organizations:
Sudan Academy of Sciences (SAS), Khartoum (Sudan)
Country of Origin:
Sudan
Language:
English
Other Identifying Numbers:
TRN: SD1100017052798
Availability:
Available from INIS in electronic form. Also available from Sudan Atomic Energy Commission, Khartoum (SD)
Submitting Site:
INIS
Size:
83 p. pages
Announcement Date:
Aug 15, 2011

Citation Formats

Osman, N O. Investigation of selected trace elements in hair samples of eczema patients. Sudan: N. p., 2010. Web.
Osman, N O. Investigation of selected trace elements in hair samples of eczema patients. Sudan.
Osman, N O. 2010. "Investigation of selected trace elements in hair samples of eczema patients." Sudan.
@misc{etde_21468025,
title = {Investigation of selected trace elements in hair samples of eczema patients}
author = {Osman, N O}
abstractNote = {The aim of this case-control study was to investigate the relationship between selected trace elements and skin diseases, namely eczema. Fifty five patients affected by the most frequent eczema types were recruited at the onset of disease at the hospital of dermatology in Khartoum together with thirty healthy controls. Fe, Zn, Cu, and Ni were measured in hair samples obtained from both patients and control group using Atomic Absorption Spectrometry (AAS). Data analysis was performed using the T-test. Partial correlation was used to study the relationship between the elemental concentration. Certified reference material (IAEA-85) Hair Powder) produced by the International Atomic Energy Agency (IAEA) was used as a quality control to check the accuracy and precision of the analytical technique, good agreement was achieved for all elements under investigation. Significant variations (p<0.05) in the concentrations of Fe, Zn, Cu, and Ni in the hair of the patients compared to the control group, and this difference was a decrease of iron, zinc and copper, therefore, should be given to the patient doses of these elements, while there was an increase in the nickel. So it is not included in the treatment. These interesting associations between the levels the of trace elements could be used as an indication for the disease as well as to monitor the treatment. Comparisons of the results obtained in the present study with those conducted for other population in the literature showed very close agreement. The levels of the elements under investigation are comparable with the data obtained from the literature for other populations with exception of Fe which was found to be very high in Sudanese population. (Author)}
place = {Sudan}
year = {2010}
month = {Dec}
}