Abstract
Objective: To investigate the effect of edaravone treatment on plasma ET-1 and CGRP levels changes in patients with traumatic intracerebral hemorrhage. Methods: Plasma ET-1 and CGRP levels were measured with RIA in 40 patients with traumatic intracerebral hemorrhage both before and after treatment with 60mg of edaravone i. v. q. d. for 5 days, 40 patients both before and after treatment with conventional treatment only (without edaravone) and 30 controls (once only). Results: The plasma ET-1 levels were significantly increased in all the patients at admission than those in controls. After treatment, the levels in all the patients dropped significantly, but the levels were significantly lower in edaravone-treated patients than those in non-edaravone-treated patients (P<0.01). The reverse was true for plasma CGRP levels. Conclusion: Edaravone treatment could correct the abnormal plasma ET-1 and CGRP levels in patients with traumatic intracerebral hemorrhage and might be beneficial to recovery. (authors)
Chunyin, Zhang;
Liang, Cai;
Jia, Guo;
Ming, Guan;
Xilun, Gan
[1]
- Department of Nuclear Medicine, The Affiliated Hospital, Luzhou Medical College, Luzhou (China)
Citation Formats
Chunyin, Zhang, Liang, Cai, Jia, Guo, Ming, Guan, and Xilun, Gan.
Study on the effect of edaravone on changes of plasma ET-1 and CGRP levels in patients with traumatic intracerebral hemorrhage.
China: N. p.,
2009.
Web.
Chunyin, Zhang, Liang, Cai, Jia, Guo, Ming, Guan, & Xilun, Gan.
Study on the effect of edaravone on changes of plasma ET-1 and CGRP levels in patients with traumatic intracerebral hemorrhage.
China.
Chunyin, Zhang, Liang, Cai, Jia, Guo, Ming, Guan, and Xilun, Gan.
2009.
"Study on the effect of edaravone on changes of plasma ET-1 and CGRP levels in patients with traumatic intracerebral hemorrhage."
China.
@misc{etde_21463440,
title = {Study on the effect of edaravone on changes of plasma ET-1 and CGRP levels in patients with traumatic intracerebral hemorrhage}
author = {Chunyin, Zhang, Liang, Cai, Jia, Guo, Ming, Guan, and Xilun, Gan}
abstractNote = {Objective: To investigate the effect of edaravone treatment on plasma ET-1 and CGRP levels changes in patients with traumatic intracerebral hemorrhage. Methods: Plasma ET-1 and CGRP levels were measured with RIA in 40 patients with traumatic intracerebral hemorrhage both before and after treatment with 60mg of edaravone i. v. q. d. for 5 days, 40 patients both before and after treatment with conventional treatment only (without edaravone) and 30 controls (once only). Results: The plasma ET-1 levels were significantly increased in all the patients at admission than those in controls. After treatment, the levels in all the patients dropped significantly, but the levels were significantly lower in edaravone-treated patients than those in non-edaravone-treated patients (P<0.01). The reverse was true for plasma CGRP levels. Conclusion: Edaravone treatment could correct the abnormal plasma ET-1 and CGRP levels in patients with traumatic intracerebral hemorrhage and might be beneficial to recovery. (authors)}
journal = []
issue = {4}
volume = {22}
place = {China}
year = {2009}
month = {Apr}
}
title = {Study on the effect of edaravone on changes of plasma ET-1 and CGRP levels in patients with traumatic intracerebral hemorrhage}
author = {Chunyin, Zhang, Liang, Cai, Jia, Guo, Ming, Guan, and Xilun, Gan}
abstractNote = {Objective: To investigate the effect of edaravone treatment on plasma ET-1 and CGRP levels changes in patients with traumatic intracerebral hemorrhage. Methods: Plasma ET-1 and CGRP levels were measured with RIA in 40 patients with traumatic intracerebral hemorrhage both before and after treatment with 60mg of edaravone i. v. q. d. for 5 days, 40 patients both before and after treatment with conventional treatment only (without edaravone) and 30 controls (once only). Results: The plasma ET-1 levels were significantly increased in all the patients at admission than those in controls. After treatment, the levels in all the patients dropped significantly, but the levels were significantly lower in edaravone-treated patients than those in non-edaravone-treated patients (P<0.01). The reverse was true for plasma CGRP levels. Conclusion: Edaravone treatment could correct the abnormal plasma ET-1 and CGRP levels in patients with traumatic intracerebral hemorrhage and might be beneficial to recovery. (authors)}
journal = []
issue = {4}
volume = {22}
place = {China}
year = {2009}
month = {Apr}
}