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Effect of Postural Change on Plasma Insulin Concentration in Normal Volunteer

Journal Article:

Abstract

The concentrations of some blood constituents are known to be influenced by the postural change. The blood glucose and insulin concentrations were measured, first, in the supine, and then (30 minutes later) in the erect positions under the fasting state. The effects of a duretic, furose-mide, were also studied under the same condition for 5 consecutive days. The materials were 5 healthy volunteers aging 20-29 years old with out any diabetic past, or family histories. The blood glucose was measured by the Nelson's method, and plasma insulin by the radioimmunoassay method. Following are the results; 1) The plasma insulin concentration in the erect position is slightly higher than in the supine position, however, the increase is statistically insignificant because of the notable individual variations in the values of the supine position. 2) Four out of 5 cases show the increase of about 80% of plasma insulin in the erect position, which is statistically significant if analyzed on the basis of frequency distribution. 3) The blood glucose concentration showed no postural changes. 4) The increase of the plasma insulin concentration in the erect position seems to the result of limited extra vasation of insulin in the lower extremities.
Authors:
Sung, Ho Kyung; Koh, Joo Whan; Joo, Jong Koo; Kim, Jin Yong; Lee, Jang Kyu [1] 
  1. Korea Atomic Research Institute, Seoul (Korea, Republic of)
Publication Date:
Mar 15, 1974
Product Type:
Journal Article
Resource Relation:
Journal Name: Korean Journal of Nuclear Medicine; Journal Volume: 8; Journal Issue: 1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BLOOD; DIABETES MELLITUS; GLUCOSE; INSULIN; PLASMA; RADIOIMMUNOASSAY; ALDEHYDES; BIOASSAY; BIOLOGICAL MATERIALS; BODY FLUIDS; CARBOHYDRATES; DIAGNOSTIC TECHNIQUES; DISEASES; ENDOCRINE DISEASES; HEXOSES; HORMONES; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; METABOLIC DISEASES; MONOSACCHARIDES; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; SACCHARIDES; TRACER TECHNIQUES
OSTI ID:
21376876
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 1225-6714; TRN: KR1003385107330
Submitting Site:
KRN
Size:
page(s) 25-28
Announcement Date:
Dec 22, 2010

Journal Article:

Citation Formats

Sung, Ho Kyung, Koh, Joo Whan, Joo, Jong Koo, Kim, Jin Yong, and Lee, Jang Kyu. Effect of Postural Change on Plasma Insulin Concentration in Normal Volunteer. Korea, Republic of: N. p., 1974. Web.
Sung, Ho Kyung, Koh, Joo Whan, Joo, Jong Koo, Kim, Jin Yong, & Lee, Jang Kyu. Effect of Postural Change on Plasma Insulin Concentration in Normal Volunteer. Korea, Republic of.
Sung, Ho Kyung, Koh, Joo Whan, Joo, Jong Koo, Kim, Jin Yong, and Lee, Jang Kyu. 1974. "Effect of Postural Change on Plasma Insulin Concentration in Normal Volunteer." Korea, Republic of.
@misc{etde_21376876,
title = {Effect of Postural Change on Plasma Insulin Concentration in Normal Volunteer}
author = {Sung, Ho Kyung, Koh, Joo Whan, Joo, Jong Koo, Kim, Jin Yong, and Lee, Jang Kyu}
abstractNote = {The concentrations of some blood constituents are known to be influenced by the postural change. The blood glucose and insulin concentrations were measured, first, in the supine, and then (30 minutes later) in the erect positions under the fasting state. The effects of a duretic, furose-mide, were also studied under the same condition for 5 consecutive days. The materials were 5 healthy volunteers aging 20-29 years old with out any diabetic past, or family histories. The blood glucose was measured by the Nelson's method, and plasma insulin by the radioimmunoassay method. Following are the results; 1) The plasma insulin concentration in the erect position is slightly higher than in the supine position, however, the increase is statistically insignificant because of the notable individual variations in the values of the supine position. 2) Four out of 5 cases show the increase of about 80% of plasma insulin in the erect position, which is statistically significant if analyzed on the basis of frequency distribution. 3) The blood glucose concentration showed no postural changes. 4) The increase of the plasma insulin concentration in the erect position seems to the result of limited extra vasation of insulin in the lower extremities.}
journal = {Korean Journal of Nuclear Medicine}
issue = {1}
volume = {8}
place = {Korea, Republic of}
year = {1974}
month = {Mar}
}