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A Clinical Study on Hypothyroidism

Abstract

A clinical study was made on 263 patients of hypothyroidism among the 5,970 patients of Various thyroid diseases diagnosed and treated at the Radioisotope Clinic and Laboratory, Seoul National University Hospital from May, 1960 to Aug, 1975. The results obtained with this study are as follows: 1) The etiological classification of hypothyroidism revealed 244 cases (93%) of primary hypothyroidism and 19 cases (7%) of secondary hypothyroidism. 2) The most frequent cause of the thyroprivic primary hypothyroidism was post radioiodine therapy with 109 cases (41.4%). 3) There were 37 cases (14%) of male and 226 cases (86%) of female, showing a ratio of 1 : 6. 4) The majority of patients were between the ages of 30 and 60 with the peak incidence (87 cases, 33%) in their fourth decades of lives. 5) The major symptoms and signs were weakness (97%), edema of face and extremities (92%); Decreased Achilles tendon reflex (87%), cold intolerance (82%), gain in weight (76%), constipation (58%) and cold skin (51%). 6) The cumulative incidence of hypothyroidism in patient treated with {sup 131}I (3-8 mci) was 7.2% at first year, 33.3% at tenth year and the 50% at fourteenth year and the annual increment was 2.9%. 7)  More>>
Authors:
Park, Keun Jo; Park, Sun Yang; Park, Jung Sik; Lee, Myung Chul; Koh, Chang Soon; Lee, Mun Ho [1] 
  1. Seoul National University College of Medicine, Seoul (Korea, Republic of)
Publication Date:
Mar 15, 1976
Product Type:
Journal Article
Resource Relation:
Journal Name: Korean Journal of Nuclear Medicine; Journal Volume: 10; Journal Issue: 1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DIAGNOSIS; HYPOTHYROIDISM; PATIENTS; THERAPY; THYROID; BODY; DISEASES; ENDOCRINE DISEASES; ENDOCRINE GLANDS; GLANDS; MEDICINE; ORGANS
OSTI ID:
21374419
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 1225-6714; TRN: KR1003370104873
Submitting Site:
KRN
Size:
page(s) 47-54
Announcement Date:
Dec 30, 2010

Citation Formats

Park, Keun Jo, Park, Sun Yang, Park, Jung Sik, Lee, Myung Chul, Koh, Chang Soon, and Lee, Mun Ho. A Clinical Study on Hypothyroidism. Korea, Republic of: N. p., 1976. Web.
Park, Keun Jo, Park, Sun Yang, Park, Jung Sik, Lee, Myung Chul, Koh, Chang Soon, & Lee, Mun Ho. A Clinical Study on Hypothyroidism. Korea, Republic of.
Park, Keun Jo, Park, Sun Yang, Park, Jung Sik, Lee, Myung Chul, Koh, Chang Soon, and Lee, Mun Ho. 1976. "A Clinical Study on Hypothyroidism." Korea, Republic of.
@misc{etde_21374419,
title = {A Clinical Study on Hypothyroidism}
author = {Park, Keun Jo, Park, Sun Yang, Park, Jung Sik, Lee, Myung Chul, Koh, Chang Soon, and Lee, Mun Ho}
abstractNote = {A clinical study was made on 263 patients of hypothyroidism among the 5,970 patients of Various thyroid diseases diagnosed and treated at the Radioisotope Clinic and Laboratory, Seoul National University Hospital from May, 1960 to Aug, 1975. The results obtained with this study are as follows: 1) The etiological classification of hypothyroidism revealed 244 cases (93%) of primary hypothyroidism and 19 cases (7%) of secondary hypothyroidism. 2) The most frequent cause of the thyroprivic primary hypothyroidism was post radioiodine therapy with 109 cases (41.4%). 3) There were 37 cases (14%) of male and 226 cases (86%) of female, showing a ratio of 1 : 6. 4) The majority of patients were between the ages of 30 and 60 with the peak incidence (87 cases, 33%) in their fourth decades of lives. 5) The major symptoms and signs were weakness (97%), edema of face and extremities (92%); Decreased Achilles tendon reflex (87%), cold intolerance (82%), gain in weight (76%), constipation (58%) and cold skin (51%). 6) The cumulative incidence of hypothyroidism in patient treated with {sup 131}I (3-8 mci) was 7.2% at first year, 33.3% at tenth year and the 50% at fourteenth year and the annual increment was 2.9%. 7) The incidence of hypothyroidism related to the numbers of {sup 131}I therapy was not linear. 8) The diagnostic compatibilities of the various tests to hypothyroidism were TSH (100%), T{sub 4} (93.8%), 24-hour-RNIU (91.5%), ATR (86.7%), T{sub 3}RU (66.1%) and BMR (64.9%).}
journal = []
issue = {1}
volume = {10}
place = {Korea, Republic of}
year = {1976}
month = {Mar}
}