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A Clinical Study on {sup 125}IT{sub 3} Resin Uptake Rate and Serum Thyroxin(T{sub 4}) in Hyperthyroidism

Abstract

Hyperthyroidism may be defined as those clinical conditions which result from an increase in the circulating levels of one or both thyroid hormones. Hyperthyroidism in broad sense could be classified with toxic diffuse goiter, toxic adenomatous goiter, and toxic multinodular goiter on the basis of the circulating thyroid hormone levels. For this study, the subject included 94 cases with hyperthyroidism were presented in 77 with toxic diffuse goiter, 8 with toxic adenomatous goiter, and 9 with toxic multinodular goiter on the levels of {sup 125}IT{sub 3} resin uptake rate and serum thyroxine (T{sub 4}). The observed results were as follows: 1) In the cases of hyperthyroidism including toxic diffuse goiter, toxic adenomatous goiter, and toxic multinodular goiter, 20.21% of the patients were male and 79.79% female. The majority of the patients were in 2nd to 4th decades of their lives. 2) There were objective signs clearly manifested in hyperthyroidism including toxic diffuse goiter and toxic adenomatous goiter which were rare in the multinodular goiter. The clinical signs in toxic diffuse and toxic adenomatous goiter included wide pulse pressure, tachycardia, systolic murmur, exophthalmos, tremor and warm skin etc. 3) The most frequent complaints of the patients with hyperthyroidism were palpitation, weight  More>>
Authors:
MooN, Ern Soo; Park, Yoh Han; Cho, Chang Ho; Park, In Soo; Lee, Chong Suk; Lee, Hak Choong [1] 
  1. National Medical Center, Seoul (Korea, Republic of)
Publication Date:
Sep 15, 1978
Product Type:
Journal Article
Resource Relation:
Journal Name: Korean Journal of Nuclear Medicine; Journal Volume: 12; Journal Issue: 2
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BLOOD SERUM; HYPERTHYROIDISM; PATIENTS; RESINS; THYROXINE; UPTAKE; AMINO ACIDS; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY FLUIDS; CARBOXYLIC ACIDS; DISEASES; ENDOCRINE DISEASES; HORMONES; MATERIALS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANIC POLYMERS; PEPTIDE HORMONES; PETROCHEMICALS; PETROLEUM PRODUCTS; POLYMERS; PROTEINS; THYROID HORMONES
OSTI ID:
21374413
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 1225-6714; TRN: KR1003354104867
Submitting Site:
KRN
Size:
page(s) 23-31
Announcement Date:
Dec 30, 2010

Citation Formats

MooN, Ern Soo, Park, Yoh Han, Cho, Chang Ho, Park, In Soo, Lee, Chong Suk, and Lee, Hak Choong. A Clinical Study on {sup 125}IT{sub 3} Resin Uptake Rate and Serum Thyroxin(T{sub 4}) in Hyperthyroidism. Korea, Republic of: N. p., 1978. Web.
MooN, Ern Soo, Park, Yoh Han, Cho, Chang Ho, Park, In Soo, Lee, Chong Suk, & Lee, Hak Choong. A Clinical Study on {sup 125}IT{sub 3} Resin Uptake Rate and Serum Thyroxin(T{sub 4}) in Hyperthyroidism. Korea, Republic of.
MooN, Ern Soo, Park, Yoh Han, Cho, Chang Ho, Park, In Soo, Lee, Chong Suk, and Lee, Hak Choong. 1978. "A Clinical Study on {sup 125}IT{sub 3} Resin Uptake Rate and Serum Thyroxin(T{sub 4}) in Hyperthyroidism." Korea, Republic of.
@misc{etde_21374413,
title = {A Clinical Study on {sup 125}IT{sub 3} Resin Uptake Rate and Serum Thyroxin(T{sub 4}) in Hyperthyroidism}
author = {MooN, Ern Soo, Park, Yoh Han, Cho, Chang Ho, Park, In Soo, Lee, Chong Suk, and Lee, Hak Choong}
abstractNote = {Hyperthyroidism may be defined as those clinical conditions which result from an increase in the circulating levels of one or both thyroid hormones. Hyperthyroidism in broad sense could be classified with toxic diffuse goiter, toxic adenomatous goiter, and toxic multinodular goiter on the basis of the circulating thyroid hormone levels. For this study, the subject included 94 cases with hyperthyroidism were presented in 77 with toxic diffuse goiter, 8 with toxic adenomatous goiter, and 9 with toxic multinodular goiter on the levels of {sup 125}IT{sub 3} resin uptake rate and serum thyroxine (T{sub 4}). The observed results were as follows: 1) In the cases of hyperthyroidism including toxic diffuse goiter, toxic adenomatous goiter, and toxic multinodular goiter, 20.21% of the patients were male and 79.79% female. The majority of the patients were in 2nd to 4th decades of their lives. 2) There were objective signs clearly manifested in hyperthyroidism including toxic diffuse goiter and toxic adenomatous goiter which were rare in the multinodular goiter. The clinical signs in toxic diffuse and toxic adenomatous goiter included wide pulse pressure, tachycardia, systolic murmur, exophthalmos, tremor and warm skin etc. 3) The most frequent complaints of the patients with hyperthyroidism were palpitation, weight loss, increased appetite, perspiration, heat intolerance, nervousness, exertional dyspnea, and menstrual disturbance etc. There was no clear difference in the incidence of symptoms between toxic diffuse goiter and toxic adenomatous goiter, but there was clear difference between toxic multinodular goiter. 4) Considering of results of {sup 125}IT{sub 3} resin uptake rate and serum T{sub 4} level in toxic diffuse goiter, toxic adenomatous goiter and toxic multinodular goiter, {sup 125}IT{sub 3} resin uptake rate was 49.15+-9.94% (mean) and serum T{sub 4} 21.29+-7.04 ug/dl (mean) in toxic diffuse goiter. In toxic multinodular goiter, {sup 125}I T{sub 3} resin uptake rate was 32.47+-6.74% (mean) and serum T{sub 4} level 11.03+-5.0 ug/dl, and then there was clear difference in the results of {sup 125}IT{sub 3} resin uptake rate and serum T-4 between toxic diffuse goiter and toxic multinodular goiter. The levels of {sup 125}IT{sub 3} uptake rate and serum T{sub 4} in toxic adenomatous goiter were 40.32+-13.08% (mean), 15.47+-8.25 ug/dl (mean) respectively, so there was no clear difference between toxic diffuse goiter and toxic adenomatous goiter. 5) There was no significant difference in length and width performed width thyroid scanning in toxic diffuse goiter, toxic adenomatous goiter, and toxic multinodular goiter.}
journal = []
issue = {2}
volume = {12}
place = {Korea, Republic of}
year = {1978}
month = {Sep}
}