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Carcinoembryonic Antigen Level in Liver Disease

Journal Article:

Abstract

Carcinoembryonic antigen was initially known as tumor specific antigen and had a potential diagnostic value in the detection of digestive tract malignancies. However, subsequent studies showed CEA and CEA-like antigen present in benign disease, particularly in liver. We had collected sera from 58 patients who had liver scan and later were diagnosed clinically and histologically as liver disease. We estimated CEA values and correlations were made with liver function tests in liver cirrhosis cases. The results: 1) The raised plasma carcinoembryonic antigen level were found in 13 (68.4%) of 19 patients cirrhosis, 5 (27.8%) of 18 patients in hepatoma, 5 (71%) of 7 patients in chronic active hepatitis, all 3 patients in liver abscesses, 2 (66.7%) of 3 patients in liver abscesses, 2 (66.7%) of 3 patients in obstructive biliary disease and none in each one patient of traumatic liver hematoma, subphrenic abscess and clonorchiasis. 2) There is no linear correlation between carcinoembryonic antigen level and liver function tests including serum bilirubin, alkaline phosphatase, SGOT and prothrombin time in liver patients.
Authors:
Choi, Kyoo Ok; Kim, Ki Whang; Park, Chang Yun [1] 
  1. Yonsei University College of Medicine, Seoul (Korea, Republic of)
Publication Date:
Sep 15, 1978
Product Type:
Journal Article
Resource Relation:
Journal Name: Korean Journal of Nuclear Medicine; Journal Volume: 12; Journal Issue: 2
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOEMBRYONIC ANTIGEN; CORRELATIONS; DIAGNOSTIC TECHNIQUES; HISTOLOGY; LIVER; LIVER CIRRHOSIS; NEOPLASMS; PATIENTS; ANTIGENS; BODY; DIGESTIVE SYSTEM; DIGESTIVE SYSTEM DISEASES; DISEASES; GLANDS; ORGANS
OSTI ID:
21374412
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 1225-6714; TRN: KR1003353104866
Submitting Site:
KRN
Size:
page(s) 17-22
Announcement Date:
Dec 22, 2010

Journal Article:

Citation Formats

Choi, Kyoo Ok, Kim, Ki Whang, and Park, Chang Yun. Carcinoembryonic Antigen Level in Liver Disease. Korea, Republic of: N. p., 1978. Web.
Choi, Kyoo Ok, Kim, Ki Whang, & Park, Chang Yun. Carcinoembryonic Antigen Level in Liver Disease. Korea, Republic of.
Choi, Kyoo Ok, Kim, Ki Whang, and Park, Chang Yun. 1978. "Carcinoembryonic Antigen Level in Liver Disease." Korea, Republic of.
@misc{etde_21374412,
title = {Carcinoembryonic Antigen Level in Liver Disease}
author = {Choi, Kyoo Ok, Kim, Ki Whang, and Park, Chang Yun}
abstractNote = {Carcinoembryonic antigen was initially known as tumor specific antigen and had a potential diagnostic value in the detection of digestive tract malignancies. However, subsequent studies showed CEA and CEA-like antigen present in benign disease, particularly in liver. We had collected sera from 58 patients who had liver scan and later were diagnosed clinically and histologically as liver disease. We estimated CEA values and correlations were made with liver function tests in liver cirrhosis cases. The results: 1) The raised plasma carcinoembryonic antigen level were found in 13 (68.4%) of 19 patients cirrhosis, 5 (27.8%) of 18 patients in hepatoma, 5 (71%) of 7 patients in chronic active hepatitis, all 3 patients in liver abscesses, 2 (66.7%) of 3 patients in liver abscesses, 2 (66.7%) of 3 patients in obstructive biliary disease and none in each one patient of traumatic liver hematoma, subphrenic abscess and clonorchiasis. 2) There is no linear correlation between carcinoembryonic antigen level and liver function tests including serum bilirubin, alkaline phosphatase, SGOT and prothrombin time in liver patients.}
journal = {Korean Journal of Nuclear Medicine}
issue = {2}
volume = {12}
place = {Korea, Republic of}
year = {1978}
month = {Sep}
}