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A Study on the Abnormalities of the Various Endocrine Functions Associated with Chronic Renal Failure

Abstract

In an attempt to evaluate the various serum hormonal changes in terminal renal failure, the fasting T{sub 4}, T{sub 3}, rT-3, gastrin, secretin prolactin, and aldosterone were measured by radioimmunoassay in 12 patients with chronic renal failure, who were admitted Chosun University Hospital from January to June, 1981. From the analysis the following results were obtained. 1. Mean values of serum hormonal concentration in 10 normal control were as follows: T{sub 4}, 12.93+-2.00 ug/ml; T{sub 3}, 113.0+-28.7 ng/ml; rT{sub 3}, 0.11+-0.10 ng/ml; gastrin, 100.0+-47.1 pg/ml; secretin, 32.46+-11.45 pg/ml; prolactin, 11.0+-3.6 ng/ml; aldosterone 137.0+-58.5 pg/ml. 2. Mean values of serum hormonal concentration in 12 chronic renal failure were as follows; T4, 7.34+-2.43 ug/ml; T3, 71.0+-19.1 ng/ml; reverse T3, 0.38+-0.19 ng/ml; gastrin, 162.5+-40.2 pg/ml; secretin, 107.50+-20.48 pg/ml; prolactin, 34.0+-17.2 ng/ml; aldosterone, 86.5+-19.8 pg/ml. 3. In chronic renal failure group, serum T4, T3, and adosterone level were significantly lower than those of the control group, but serum rT-3, gastrin, secretin and prolactin were significantly higher than those of the control group. 4. In the view of the correlation between serum hormonal concentrations and serum creatine levels in patients with chronic renal failure, rT{sub 3}, gastrin, secretin and prolactin showed increasing tendency (positive correlations),  More>>
Authors:
Hong, Chan Pyo; Kim, Man Woo; Rho, Bang Soo; Jang, Kyung Sik; Lee, Min Hyung; Oh, Hyun Kwan [1] 
  1. Chosun University College of Medicine, Seoul (Korea, Republic of)
Publication Date:
Mar 15, 1982
Product Type:
Journal Article
Resource Relation:
Journal Name: Korean Journal of Nuclear Medicine; Journal Volume: 16; Journal Issue: 1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CORRELATIONS; ENDOCRINE DISEASES; FAILURES; PATIENTS; RENAL CLEARANCE; CLEARANCE; DISEASES; EXCRETION
OSTI ID:
21370236
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 1225-6714; TRN: KR1003242100690
Submitting Site:
KRN
Size:
page(s) 7-14
Announcement Date:
Dec 30, 2010

Citation Formats

Hong, Chan Pyo, Kim, Man Woo, Rho, Bang Soo, Jang, Kyung Sik, Lee, Min Hyung, and Oh, Hyun Kwan. A Study on the Abnormalities of the Various Endocrine Functions Associated with Chronic Renal Failure. Korea, Republic of: N. p., 1982. Web.
Hong, Chan Pyo, Kim, Man Woo, Rho, Bang Soo, Jang, Kyung Sik, Lee, Min Hyung, & Oh, Hyun Kwan. A Study on the Abnormalities of the Various Endocrine Functions Associated with Chronic Renal Failure. Korea, Republic of.
Hong, Chan Pyo, Kim, Man Woo, Rho, Bang Soo, Jang, Kyung Sik, Lee, Min Hyung, and Oh, Hyun Kwan. 1982. "A Study on the Abnormalities of the Various Endocrine Functions Associated with Chronic Renal Failure." Korea, Republic of.
@misc{etde_21370236,
title = {A Study on the Abnormalities of the Various Endocrine Functions Associated with Chronic Renal Failure}
author = {Hong, Chan Pyo, Kim, Man Woo, Rho, Bang Soo, Jang, Kyung Sik, Lee, Min Hyung, and Oh, Hyun Kwan}
abstractNote = {In an attempt to evaluate the various serum hormonal changes in terminal renal failure, the fasting T{sub 4}, T{sub 3}, rT-3, gastrin, secretin prolactin, and aldosterone were measured by radioimmunoassay in 12 patients with chronic renal failure, who were admitted Chosun University Hospital from January to June, 1981. From the analysis the following results were obtained. 1. Mean values of serum hormonal concentration in 10 normal control were as follows: T{sub 4}, 12.93+-2.00 ug/ml; T{sub 3}, 113.0+-28.7 ng/ml; rT{sub 3}, 0.11+-0.10 ng/ml; gastrin, 100.0+-47.1 pg/ml; secretin, 32.46+-11.45 pg/ml; prolactin, 11.0+-3.6 ng/ml; aldosterone 137.0+-58.5 pg/ml. 2. Mean values of serum hormonal concentration in 12 chronic renal failure were as follows; T4, 7.34+-2.43 ug/ml; T3, 71.0+-19.1 ng/ml; reverse T3, 0.38+-0.19 ng/ml; gastrin, 162.5+-40.2 pg/ml; secretin, 107.50+-20.48 pg/ml; prolactin, 34.0+-17.2 ng/ml; aldosterone, 86.5+-19.8 pg/ml. 3. In chronic renal failure group, serum T4, T3, and adosterone level were significantly lower than those of the control group, but serum rT-3, gastrin, secretin and prolactin were significantly higher than those of the control group. 4. In the view of the correlation between serum hormonal concentrations and serum creatine levels in patients with chronic renal failure, rT{sub 3}, gastrin, secretin and prolactin showed increasing tendency (positive correlations), whereas T{sub 4}, T{sub 3} and aldosterone showed decreasing tendency (negative correlations) with increment of serum creatinine levels. And so, we observed the negative correlation between T{sub 3} and rT{sub 3}.}
journal = []
issue = {1}
volume = {16}
place = {Korea, Republic of}
year = {1982}
month = {Mar}
}