Abstract
Regional cerebral blood flow were measured in 10 patients with Parkinson's disease and 12 normal persons using {sup 99m}Tc-HMPAO SPECT. Reconstructed images were interpreted qualitatively and were compared with those findings of CT. For the quantitative analysis, six pairs of region of interest matched with the perfusion territories of large cerebral arteries and cerebellar hemisphere were determined. From the count values, indices showing the degree of asymmetry between right and left cerebral or cerebellar hemisphere, cerebral asymmetry index (ASI) and percent index of cerebellar asymmetry (PIA), and an index showing change of each region, region to cerebellum ratio (RCR) were obtained. ASI of normal persons and patients were 0.082 +- 0.033 and 0.108 +- 0.062, respectively and PIA were -0.4 +- 0.7% and -0.7 +- 1.0%, respectively, which showed no statistically significant difference between normal persons and patients. Among 10 RCR's, those of both regions of basal ganglia and both regions of anterior cerebral artery were significantly reduced. We concluded that the most significant reduction of regional cerebral blood flow in patients with Parkinson's disease was observed in the regions of basal ganglia and in the regions of anterior cerebral artery, and the degree of change in hemispheric blood flow
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Lee, Myung Chul;
Bae, Sang Kyun;
Chung, June Key;
Koh, Chang Soon;
Roh, Jae Kyu;
Myung, Ho Jin;
[1]
Lee, Myung Hae
[2]
- Seoul National University College of Medicine, Seoul (Korea, Republic of)
- Asan Medical Center, Seoul (Korea, Republic of)
Citation Formats
Lee, Myung Chul, Bae, Sang Kyun, Chung, June Key, Koh, Chang Soon, Roh, Jae Kyu, Myung, Ho Jin, and Lee, Myung Hae.
Quantitative Analysis of Regional Cerebral Blood Flow using {sup 99m}Tc-HMPAO SPECT in Parkinson's Disease.
Korea, Republic of: N. p.,
1992.
Web.
Lee, Myung Chul, Bae, Sang Kyun, Chung, June Key, Koh, Chang Soon, Roh, Jae Kyu, Myung, Ho Jin, & Lee, Myung Hae.
Quantitative Analysis of Regional Cerebral Blood Flow using {sup 99m}Tc-HMPAO SPECT in Parkinson's Disease.
Korea, Republic of.
Lee, Myung Chul, Bae, Sang Kyun, Chung, June Key, Koh, Chang Soon, Roh, Jae Kyu, Myung, Ho Jin, and Lee, Myung Hae.
1992.
"Quantitative Analysis of Regional Cerebral Blood Flow using {sup 99m}Tc-HMPAO SPECT in Parkinson's Disease."
Korea, Republic of.
@misc{etde_21358983,
title = {Quantitative Analysis of Regional Cerebral Blood Flow using {sup 99m}Tc-HMPAO SPECT in Parkinson's Disease}
author = {Lee, Myung Chul, Bae, Sang Kyun, Chung, June Key, Koh, Chang Soon, Roh, Jae Kyu, Myung, Ho Jin, and Lee, Myung Hae}
abstractNote = {Regional cerebral blood flow were measured in 10 patients with Parkinson's disease and 12 normal persons using {sup 99m}Tc-HMPAO SPECT. Reconstructed images were interpreted qualitatively and were compared with those findings of CT. For the quantitative analysis, six pairs of region of interest matched with the perfusion territories of large cerebral arteries and cerebellar hemisphere were determined. From the count values, indices showing the degree of asymmetry between right and left cerebral or cerebellar hemisphere, cerebral asymmetry index (ASI) and percent index of cerebellar asymmetry (PIA), and an index showing change of each region, region to cerebellum ratio (RCR) were obtained. ASI of normal persons and patients were 0.082 +- 0.033 and 0.108 +- 0.062, respectively and PIA were -0.4 +- 0.7% and -0.7 +- 1.0%, respectively, which showed no statistically significant difference between normal persons and patients. Among 10 RCR's, those of both regions of basal ganglia and both regions of anterior cerebral artery were significantly reduced. We concluded that the most significant reduction of regional cerebral blood flow in patients with Parkinson's disease was observed in the regions of basal ganglia and in the regions of anterior cerebral artery, and the degree of change in hemispheric blood flow was similar in both hemisphere.}
journal = []
issue = {2}
volume = {26}
place = {Korea, Republic of}
year = {1992}
month = {Jul}
}
title = {Quantitative Analysis of Regional Cerebral Blood Flow using {sup 99m}Tc-HMPAO SPECT in Parkinson's Disease}
author = {Lee, Myung Chul, Bae, Sang Kyun, Chung, June Key, Koh, Chang Soon, Roh, Jae Kyu, Myung, Ho Jin, and Lee, Myung Hae}
abstractNote = {Regional cerebral blood flow were measured in 10 patients with Parkinson's disease and 12 normal persons using {sup 99m}Tc-HMPAO SPECT. Reconstructed images were interpreted qualitatively and were compared with those findings of CT. For the quantitative analysis, six pairs of region of interest matched with the perfusion territories of large cerebral arteries and cerebellar hemisphere were determined. From the count values, indices showing the degree of asymmetry between right and left cerebral or cerebellar hemisphere, cerebral asymmetry index (ASI) and percent index of cerebellar asymmetry (PIA), and an index showing change of each region, region to cerebellum ratio (RCR) were obtained. ASI of normal persons and patients were 0.082 +- 0.033 and 0.108 +- 0.062, respectively and PIA were -0.4 +- 0.7% and -0.7 +- 1.0%, respectively, which showed no statistically significant difference between normal persons and patients. Among 10 RCR's, those of both regions of basal ganglia and both regions of anterior cerebral artery were significantly reduced. We concluded that the most significant reduction of regional cerebral blood flow in patients with Parkinson's disease was observed in the regions of basal ganglia and in the regions of anterior cerebral artery, and the degree of change in hemispheric blood flow was similar in both hemisphere.}
journal = []
issue = {2}
volume = {26}
place = {Korea, Republic of}
year = {1992}
month = {Jul}
}