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Inflammatory myofibroblastic tumor of the mesentery associated with high fever and positive Widal test

Journal Article:

Abstract

Inflammatory myofibroblastic tumor (IMT) is associated in 15-30% of cases with systemic symptomatology , such as prolonged fever, weight loss, elevated erythrocyte sedimentation rate (ESR) , anemia, thrombocytosis and leukocytosis. We report the case of a 4-year-old Lebanese boy who presented with high-grade fever of long duration and a single (unpaired) positive Widal agglutination test. Blood culture was negative. A diagnosis of typhoid fever was made. An abdominal (mesenteric) IMT was incidentally discovered, 30 days after the fever had appeared. After surgery, the fever disappeared immediately, and the ESR returned. We strongly favor the possibility of a false positive Widal test, due to polyclonal increase in serum immunoglobulins, which often occurs in IMT. We also think that IMT might be a mimicker of typhoid fever, both clinically and serologically. Physicians, especially pediatricians practicing in endemic areas, should probably be aware of this mimicry. (author)
Authors:
Chouairy, Camil J; [1]  Bechara, Elie A; Ghabril, Ramy H; [2]  Gebran, Sleiman J [3] 
  1. Dept. of Pathology, Saint George Hospital, Beirut (Lebanon)
  2. Dept. of Pediatrics, Saint George Hospital, Beirut (Lebanon)
  3. Dept. of Pediatric Surgery, AlHada Armed Forces Hospital, Taif (Saudi Arabia)
Publication Date:
Jul 01, 2008
Product Type:
Journal Article
Resource Relation:
Journal Name: Saudi Medical Journal; Journal Volume: 29; Journal Issue: 12
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ANEMIAS; CLINICAL TRIALS; DIAGNOSIS; MESENTERY; NEOPLASMS; PATHOLOGY; PATIENTS; PEDIATRICS; SAUDI ARABIA; ARAB COUNTRIES; ASIA; DEVELOPING COUNTRIES; DISEASES; HEMIC DISEASES; MEDICINE; MEMBRANES; MIDDLE EAST; SEROUS MEMBRANES; SYMPTOMS; TESTING
OSTI ID:
21357389
Country of Origin:
Saudi Arabia
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0379-5284; TRN: SA1000212092128
Submitting Site:
INIS
Size:
page(s) 1819-1823
Announcement Date:
Nov 19, 2010

Journal Article:

Citation Formats

Chouairy, Camil J, Bechara, Elie A, Ghabril, Ramy H, and Gebran, Sleiman J. Inflammatory myofibroblastic tumor of the mesentery associated with high fever and positive Widal test. Saudi Arabia: N. p., 2008. Web.
Chouairy, Camil J, Bechara, Elie A, Ghabril, Ramy H, & Gebran, Sleiman J. Inflammatory myofibroblastic tumor of the mesentery associated with high fever and positive Widal test. Saudi Arabia.
Chouairy, Camil J, Bechara, Elie A, Ghabril, Ramy H, and Gebran, Sleiman J. 2008. "Inflammatory myofibroblastic tumor of the mesentery associated with high fever and positive Widal test." Saudi Arabia.
@misc{etde_21357389,
title = {Inflammatory myofibroblastic tumor of the mesentery associated with high fever and positive Widal test}
author = {Chouairy, Camil J, Bechara, Elie A, Ghabril, Ramy H, and Gebran, Sleiman J}
abstractNote = {Inflammatory myofibroblastic tumor (IMT) is associated in 15-30% of cases with systemic symptomatology , such as prolonged fever, weight loss, elevated erythrocyte sedimentation rate (ESR) , anemia, thrombocytosis and leukocytosis. We report the case of a 4-year-old Lebanese boy who presented with high-grade fever of long duration and a single (unpaired) positive Widal agglutination test. Blood culture was negative. A diagnosis of typhoid fever was made. An abdominal (mesenteric) IMT was incidentally discovered, 30 days after the fever had appeared. After surgery, the fever disappeared immediately, and the ESR returned. We strongly favor the possibility of a false positive Widal test, due to polyclonal increase in serum immunoglobulins, which often occurs in IMT. We also think that IMT might be a mimicker of typhoid fever, both clinically and serologically. Physicians, especially pediatricians practicing in endemic areas, should probably be aware of this mimicry. (author)}
journal = {Saudi Medical Journal}
issue = {12}
volume = {29}
place = {Saudi Arabia}
year = {2008}
month = {Jul}
}