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Comparison of side effects in myelography with iopamidol and metrizamide

Abstract

The study was conducted to compare the side effects in myelography of the two non-ionic water-soluble contrast medias, lopamidol (Niopam) and Metrizamide (Amipaque). A total of 111 patients were examined, 64 with lopamidol and 47 with Metrizamide. Side effects consisted of headache, nausea, vomiting, dizziness, urinary difficulty, muscular pain, seizure, neurobehavioral disturbance, neurological sign change, vital sign change and etc. The common side effects were headache, nausea, vomiting and dizziness in order of frequency. Most of the side effects were subsided within 24 hours following myelography. lopamidol myelography caused fewer and milder side effects than Metrizamide study. The side effects were more commonly observed in cervical, thoracic or total myelography than in lumbar myelography with either lopamidol or Metrizamide. There was no significant correlation between incidence of the side effects and premedication with phenobarbital or valium injection before myelography and CSF sampling during the procedure.
Authors:
Lee, Yong; Kang, Heung Sik; Chang, Kee Hyun; Han, Seoul Heui; Kwon, Oh Sung; Myung, Ho Gin [1] 
  1. Seoul National University College of Medicine, Seoul (Korea, Republic of)
Publication Date:
Dec 15, 1986
Product Type:
Journal Article
Resource Relation:
Journal Name: Journal of the Korean Radiological Society; Journal Volume: 22; Journal Issue: 6
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CORRELATIONS; INJECTION; IOPAMIDOL; METRIZAMIDE; MYELOID LEUKEMIA; PATIENTS; AMIDES; CONTRAST MEDIA; DISEASES; IMMUNE SYSTEM DISEASES; INTAKE; LEUKEMIA; NEOPLASMS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS
OSTI ID:
21343763
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 0301-2867; TRN: KR1001091074641
Submitting Site:
KRN
Size:
page(s) 953-960
Announcement Date:
Oct 28, 2010

Citation Formats

Lee, Yong, Kang, Heung Sik, Chang, Kee Hyun, Han, Seoul Heui, Kwon, Oh Sung, and Myung, Ho Gin. Comparison of side effects in myelography with iopamidol and metrizamide. Korea, Republic of: N. p., 1986. Web.
Lee, Yong, Kang, Heung Sik, Chang, Kee Hyun, Han, Seoul Heui, Kwon, Oh Sung, & Myung, Ho Gin. Comparison of side effects in myelography with iopamidol and metrizamide. Korea, Republic of.
Lee, Yong, Kang, Heung Sik, Chang, Kee Hyun, Han, Seoul Heui, Kwon, Oh Sung, and Myung, Ho Gin. 1986. "Comparison of side effects in myelography with iopamidol and metrizamide." Korea, Republic of.
@misc{etde_21343763,
title = {Comparison of side effects in myelography with iopamidol and metrizamide}
author = {Lee, Yong, Kang, Heung Sik, Chang, Kee Hyun, Han, Seoul Heui, Kwon, Oh Sung, and Myung, Ho Gin}
abstractNote = {The study was conducted to compare the side effects in myelography of the two non-ionic water-soluble contrast medias, lopamidol (Niopam) and Metrizamide (Amipaque). A total of 111 patients were examined, 64 with lopamidol and 47 with Metrizamide. Side effects consisted of headache, nausea, vomiting, dizziness, urinary difficulty, muscular pain, seizure, neurobehavioral disturbance, neurological sign change, vital sign change and etc. The common side effects were headache, nausea, vomiting and dizziness in order of frequency. Most of the side effects were subsided within 24 hours following myelography. lopamidol myelography caused fewer and milder side effects than Metrizamide study. The side effects were more commonly observed in cervical, thoracic or total myelography than in lumbar myelography with either lopamidol or Metrizamide. There was no significant correlation between incidence of the side effects and premedication with phenobarbital or valium injection before myelography and CSF sampling during the procedure.}
journal = []
issue = {6}
volume = {22}
place = {Korea, Republic of}
year = {1986}
month = {Dec}
}