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Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience

Abstract

Purpose: This study aimed to determine the success and complication rates of radiofrequency ablation (RFA) in treatment of osteoid osteoma (OO) and duration of pain relief. Furthermore value of bone biopsy prior to the RFA was evaluated. Materials and methods: Within 61 months 39 patients (23 male, 16 female, 7-53 years, mean 18.7 years, median 17 years) suffering from osteoid osteoma were treated. Lesions were located in femur (n = 20), tibia (n = 10), spine (n = 5), humerus (n = 1), radius (n = 1), talus (n = 1) and pelvis (n = 1). In children, RFA was performed under general anaesthesia, in adults conscious sedation was preferred. In 29 of 39 (74%) lesion biopsies were obtained. Cooling of skin was performed in OOs located in bones with minor soft tissue covering (tibia, radius) and saline flushing via an additional needle was performed if the OO was adjacent to nerval structures. Primary success rate, complications, symptom-free interval, follow-up and biopsy results were evaluated. Results: Within observation period (1-61 months; median: 32 months) 38 of 39 patients were successfully treated and had no more complaints. In 3 of 38 patients relapse occurred after 1, 14 and 32 months and  More>>
Authors:
Hoffmann, Ralf-Thorsten; [1]  Jakobs, Tobias F. , E-mail: tobias.jakobs@med.uni-muenchen.de; [1]  Kubisch, Constanze H. , E-mail: constanze.kubisch@med.uni-muenchen.de; [2]  Trumm, Christoph G. , E-mail: christoph.trumm@med.uni-muenchen.de; [1]  Weber, Christof; [3]  Duerr, Hans-Roland; [4]  Helmberger, Thomas K. , E-mail: thomas.helmberger@kh-bogenhausen.de; [5]  Reiser, Maximilian F. , E-mail: maximilian.reiser@med.uni-muenchen.de [1] 
  1. Institute of Clinical Radiology, Ludwig Maximilians-University, Campus Grosshadern, Marchioninistrasse 15, 81377 Munich (Germany)
  2. Department of Medicine/Gastroenterology, Ludwig Maximilians-University, Campus Grosshadern, Marchioninistrasse 15, 81377 Munich (Germany)
  3. Institute of Diagnostic and Interventional Radiology, Klinikum - Deggendorf, Perlasbergerstr. 41, 94469 Deggendorf (Germany)
  4. Department of Orthopedic Surgery, Ludwig Maximilians-University, Campus Grosshadern, Marchioninistrasse 15, 81377 Munich (Germany)
  5. Institute of Radiology and Nuclear Medicine, Klinikum Bogenhausen, Englschalkinger Str. 77, 81925 Munich (Germany)
Publication Date:
Feb 15, 2010
Product Type:
Journal Article
Resource Relation:
Journal Name: European Journal of Radiology; Journal Volume: 73; Journal Issue: 2; Other Information: DOI: 10.1016/j.ejrad.2008.11.018; PII: S0720-048X(08)00649-9; Copyright (c) 2008 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA)
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ABLATION; BIOPSY; DIAGNOSIS; FEMUR; FLUOROSCOPY; NEOPLASMS; PATIENTS; PELVIS; RADIOWAVE RADIATION; TIBIA; VERTEBRAE
OSTI ID:
21324888
Country of Origin:
Netherlands
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0720-048X; EJRADR; TRN: NL10R1137066216
Availability:
Available from http://dx.doi.org/10.1016/j.ejrad.2008.11.018;INIS
Submitting Site:
NLN
Size:
page(s) 374-379
Announcement Date:
Aug 26, 2010

Citation Formats

Hoffmann, Ralf-Thorsten, Jakobs, Tobias F. , E-mail: tobias.jakobs@med.uni-muenchen.de, Kubisch, Constanze H. , E-mail: constanze.kubisch@med.uni-muenchen.de, Trumm, Christoph G. , E-mail: christoph.trumm@med.uni-muenchen.de, Weber, Christof, Duerr, Hans-Roland, Helmberger, Thomas K. , E-mail: thomas.helmberger@kh-bogenhausen.de, and Reiser, Maximilian F. , E-mail: maximilian.reiser@med.uni-muenchen.de. Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience. Netherlands: N. p., 2010. Web. doi:10.1016/j.ejrad.2008.11.018.
Hoffmann, Ralf-Thorsten, Jakobs, Tobias F. , E-mail: tobias.jakobs@med.uni-muenchen.de, Kubisch, Constanze H. , E-mail: constanze.kubisch@med.uni-muenchen.de, Trumm, Christoph G. , E-mail: christoph.trumm@med.uni-muenchen.de, Weber, Christof, Duerr, Hans-Roland, Helmberger, Thomas K. , E-mail: thomas.helmberger@kh-bogenhausen.de, & Reiser, Maximilian F. , E-mail: maximilian.reiser@med.uni-muenchen.de. Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience. Netherlands. https://doi.org/10.1016/j.ejrad.2008.11.018
Hoffmann, Ralf-Thorsten, Jakobs, Tobias F. , E-mail: tobias.jakobs@med.uni-muenchen.de, Kubisch, Constanze H. , E-mail: constanze.kubisch@med.uni-muenchen.de, Trumm, Christoph G. , E-mail: christoph.trumm@med.uni-muenchen.de, Weber, Christof, Duerr, Hans-Roland, Helmberger, Thomas K. , E-mail: thomas.helmberger@kh-bogenhausen.de, and Reiser, Maximilian F. , E-mail: maximilian.reiser@med.uni-muenchen.de. 2010. "Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience." Netherlands. https://doi.org/10.1016/j.ejrad.2008.11.018.
@misc{etde_21324888,
title = {Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience}
author = {Hoffmann, Ralf-Thorsten, Jakobs, Tobias F. , E-mail: tobias.jakobs@med.uni-muenchen.de, Kubisch, Constanze H. , E-mail: constanze.kubisch@med.uni-muenchen.de, Trumm, Christoph G. , E-mail: christoph.trumm@med.uni-muenchen.de, Weber, Christof, Duerr, Hans-Roland, Helmberger, Thomas K. , E-mail: thomas.helmberger@kh-bogenhausen.de, and Reiser, Maximilian F. , E-mail: maximilian.reiser@med.uni-muenchen.de}
abstractNote = {Purpose: This study aimed to determine the success and complication rates of radiofrequency ablation (RFA) in treatment of osteoid osteoma (OO) and duration of pain relief. Furthermore value of bone biopsy prior to the RFA was evaluated. Materials and methods: Within 61 months 39 patients (23 male, 16 female, 7-53 years, mean 18.7 years, median 17 years) suffering from osteoid osteoma were treated. Lesions were located in femur (n = 20), tibia (n = 10), spine (n = 5), humerus (n = 1), radius (n = 1), talus (n = 1) and pelvis (n = 1). In children, RFA was performed under general anaesthesia, in adults conscious sedation was preferred. In 29 of 39 (74%) lesion biopsies were obtained. Cooling of skin was performed in OOs located in bones with minor soft tissue covering (tibia, radius) and saline flushing via an additional needle was performed if the OO was adjacent to nerval structures. Primary success rate, complications, symptom-free interval, follow-up and biopsy results were evaluated. Results: Within observation period (1-61 months; median: 32 months) 38 of 39 patients were successfully treated and had no more complaints. In 3 of 38 patients relapse occurred after 1, 14 and 32 months and RFA was repeated. Two major complications (broken drill, infection) and 2 minor complications (hematoma, prolonged pain) were observed. Biopsy was able to prove diagnosis in 14 of 29 (48%) cases. Conclusions: Biopsy prior to treatment is not mandatory due to a remarkable amount of false negative findings in clinically and morphologically unambiguous cases of OO. RFA is a highly effective, efficient, minimally invasive and safe method for the treatment of OO.}
doi = {10.1016/j.ejrad.2008.11.018}
journal = []
issue = {2}
volume = {73}
place = {Netherlands}
year = {2010}
month = {Feb}
}