You need JavaScript to view this

The Virtual Family-development of surface-based anatomical models of two adults and two children for dosimetric simulations

Abstract

The objective of this study was to develop anatomically correct whole body human models of an adult male (34 years old), an adult female (26 years old) and two children (an 11-year-old girl and a six-year-old boy) for the optimized evaluation of electromagnetic exposure. These four models are referred to as the Virtual Family. They are based on high resolution magnetic resonance (MR) images of healthy volunteers. More than 80 different tissue types were distinguished during the segmentation. To improve the accuracy and the effectiveness of the segmentation, a novel semi-automated tool was used to analyze and segment the data. All tissues and organs were reconstructed as three-dimensional (3D) unstructured triangulated surface objects, yielding high precision images of individual features of the body. This greatly enhances the meshing flexibility and the accuracy with respect to thin tissue layers and small organs in comparison with the traditional voxel-based representation of anatomical models. Conformal computational techniques were also applied. The techniques and tools developed in this study can be used to more effectively develop future models and further improve the accuracy of the models for various applications. For research purposes, the four models are provided for free to the scientific community. (note)
Authors:
Christ, Andreas; Honegger, Katharina; Zefferer, Marcel; Neufeld, Esra; Oberle, Michael; Szczerba, Dominik; Kuster, Niels; [1]  Kainz, Wolfgang; Guag, Joshua W; [2]  Hahn, Eckhart G; Rascher, Wolfgang; Janka, Rolf; Bautz, Werner; [3]  Chen, Ji; Shen, Jianxiang; [4]  Kiefer, Berthold; Schmitt, Peter; Hollenbach, Hans-Peter; [5]  Kam, Anthony [6] 
  1. Foundation for Research on Information Technologies in Society (IT'IS), Zeughausstr. 43, 8004 Zuerich (Switzerland)
  2. US Food and Drug Administration (FDA), Center for Devices and Radiological Health (CDRH), Silver Spring, MD 20993 (United States)
  3. Universitaetsklinikum Erlangen, Friedrich-Alexander Universitaet Erlangen-Nuernberg, 91054 Erlangen (Germany)
  4. Department of Electrical and Computer Engineering, The University of Houston, Houston, TX 77204 (United States)
  5. Siemens Healthcare, MR-Application Development, 91052 Erlangen (Germany)
  6. Department of Imaging, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224 (United States)
Publication Date:
Jan 21, 2010
Product Type:
Journal Article
Resource Relation:
Journal Name: Physics in Medicine and Biology; Journal Volume: 55; Journal Issue: 2; Other Information: PII: S0031-9155(10)24846-7; DOI: 10.1088/0031-9155/55/2/N01; Country of input: International Atomic Energy Agency (IAEA)
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACCURACY; ADULTS; ANIMAL TISSUES; CHILDREN; IMAGES; MAGNETIC RESONANCE; ORGANS; PHANTOMS; SIMULATION; THREE-DIMENSIONAL CALCULATIONS
OSTI ID:
21323791
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0031-9155; PHMBA7; TRN: GB10O6768065075
Availability:
Available from http://dx.doi.org/10.1088/0031-9155/55/2/N01;INIS
Submitting Site:
GBN
Size:
page(s) N23-N38
Announcement Date:
Aug 26, 2010

Citation Formats

Christ, Andreas, Honegger, Katharina, Zefferer, Marcel, Neufeld, Esra, Oberle, Michael, Szczerba, Dominik, Kuster, Niels, Kainz, Wolfgang, Guag, Joshua W, Hahn, Eckhart G, Rascher, Wolfgang, Janka, Rolf, Bautz, Werner, Chen, Ji, Shen, Jianxiang, Kiefer, Berthold, Schmitt, Peter, Hollenbach, Hans-Peter, and Kam, Anthony. The Virtual Family-development of surface-based anatomical models of two adults and two children for dosimetric simulations. United Kingdom: N. p., 2010. Web. doi:10.1088/0031-9155/55/2/N01; COUNTRY OF INPUT: INTERNATIONAL ATOMIC ENERGY AGENCY (IAEA).
Christ, Andreas, Honegger, Katharina, Zefferer, Marcel, Neufeld, Esra, Oberle, Michael, Szczerba, Dominik, Kuster, Niels, Kainz, Wolfgang, Guag, Joshua W, Hahn, Eckhart G, Rascher, Wolfgang, Janka, Rolf, Bautz, Werner, Chen, Ji, Shen, Jianxiang, Kiefer, Berthold, Schmitt, Peter, Hollenbach, Hans-Peter, & Kam, Anthony. The Virtual Family-development of surface-based anatomical models of two adults and two children for dosimetric simulations. United Kingdom. https://doi.org/10.1088/0031-9155/55/2/N01; COUNTRY OF INPUT: INTERNATIONAL ATOMIC ENERGY AGENCY (IAEA)
Christ, Andreas, Honegger, Katharina, Zefferer, Marcel, Neufeld, Esra, Oberle, Michael, Szczerba, Dominik, Kuster, Niels, Kainz, Wolfgang, Guag, Joshua W, Hahn, Eckhart G, Rascher, Wolfgang, Janka, Rolf, Bautz, Werner, Chen, Ji, Shen, Jianxiang, Kiefer, Berthold, Schmitt, Peter, Hollenbach, Hans-Peter, and Kam, Anthony. 2010. "The Virtual Family-development of surface-based anatomical models of two adults and two children for dosimetric simulations." United Kingdom. https://doi.org/10.1088/0031-9155/55/2/N01; COUNTRY OF INPUT: INTERNATIONAL ATOMIC ENERGY AGENCY (IAEA).
@misc{etde_21323791,
title = {The Virtual Family-development of surface-based anatomical models of two adults and two children for dosimetric simulations}
author = {Christ, Andreas, Honegger, Katharina, Zefferer, Marcel, Neufeld, Esra, Oberle, Michael, Szczerba, Dominik, Kuster, Niels, Kainz, Wolfgang, Guag, Joshua W, Hahn, Eckhart G, Rascher, Wolfgang, Janka, Rolf, Bautz, Werner, Chen, Ji, Shen, Jianxiang, Kiefer, Berthold, Schmitt, Peter, Hollenbach, Hans-Peter, and Kam, Anthony}
abstractNote = {The objective of this study was to develop anatomically correct whole body human models of an adult male (34 years old), an adult female (26 years old) and two children (an 11-year-old girl and a six-year-old boy) for the optimized evaluation of electromagnetic exposure. These four models are referred to as the Virtual Family. They are based on high resolution magnetic resonance (MR) images of healthy volunteers. More than 80 different tissue types were distinguished during the segmentation. To improve the accuracy and the effectiveness of the segmentation, a novel semi-automated tool was used to analyze and segment the data. All tissues and organs were reconstructed as three-dimensional (3D) unstructured triangulated surface objects, yielding high precision images of individual features of the body. This greatly enhances the meshing flexibility and the accuracy with respect to thin tissue layers and small organs in comparison with the traditional voxel-based representation of anatomical models. Conformal computational techniques were also applied. The techniques and tools developed in this study can be used to more effectively develop future models and further improve the accuracy of the models for various applications. For research purposes, the four models are provided for free to the scientific community. (note)}
doi = {10.1088/0031-9155/55/2/N01; COUNTRY OF INPUT: INTERNATIONAL ATOMIC ENERGY AGENCY (IAEA)}
journal = []
issue = {2}
volume = {55}
place = {United Kingdom}
year = {2010}
month = {Jan}
}