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The radioimmunoassay of serum alpha-fetoprotein levels

Journal Article:

Abstract

Alpha-fetoprotein (AFP) was first described in the human fetus in 1956 and became a marker protein of primary liver cancer in adults. Serum AFP levels were measured by radioimmunoassay in 212 patients with a variety of malignant and nonmalignant diseases to determine the incidence of leveis elevated above 40 ng/ml. The results obtained are as follows: In 44 cases of total 212 patients, abnormal AFP levels above 40 ng/ml in serum were measured; 24 of 31 patients with primary hepatocellular carcinoma and primary hepatocellular carcinoma with liver cirrhosis (77.4%), 7 of 51 patients with only liver cirrhosis (13.7%), 4 of 10 patients with metastatic liver cancer (40.0%), 4 of 15 patients with chronic hepatitis (26.7%), 2 of 23 patients with acute hepatitis (8.7%), and each one patient with 6 pancreatic carcinoma and 9 cholangiocarcinoma had elevated serum AFP levels. One pregnant woman with gestation 35 weeks had elevated level, but within normal limit during pregnancy.
Authors:
Kim, Y H; Choi, K A; Ahn, K S; Suh, W H; Lee, M J [1] 
  1. Korea University College of Medicine, Seoul (Korea, Republic of)
Publication Date:
Jun 15, 1982
Product Type:
Journal Article
Resource Relation:
Journal Name: Journal of the Korean Radiological Society; Journal Volume: 18; Journal Issue: 2; Other Information: 28 refs, 5 tabs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ADULTS; BLOOD SERUM; FETUSES; LIVER; LIVER CIRRHOSIS; NEOPLASMS; PATIENTS; RADIOIMMUNOASSAY
OSTI ID:
21211850
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 1738-2637; DBSHAH; TRN: KR0902679082099
Submitting Site:
KRN
Size:
page(s) 401-407
Announcement Date:
Sep 24, 2009

Journal Article:

Citation Formats

Kim, Y H, Choi, K A, Ahn, K S, Suh, W H, and Lee, M J. The radioimmunoassay of serum alpha-fetoprotein levels. Korea, Republic of: N. p., 1982. Web.
Kim, Y H, Choi, K A, Ahn, K S, Suh, W H, & Lee, M J. The radioimmunoassay of serum alpha-fetoprotein levels. Korea, Republic of.
Kim, Y H, Choi, K A, Ahn, K S, Suh, W H, and Lee, M J. 1982. "The radioimmunoassay of serum alpha-fetoprotein levels." Korea, Republic of.
@misc{etde_21211850,
title = {The radioimmunoassay of serum alpha-fetoprotein levels}
author = {Kim, Y H, Choi, K A, Ahn, K S, Suh, W H, and Lee, M J}
abstractNote = {Alpha-fetoprotein (AFP) was first described in the human fetus in 1956 and became a marker protein of primary liver cancer in adults. Serum AFP levels were measured by radioimmunoassay in 212 patients with a variety of malignant and nonmalignant diseases to determine the incidence of leveis elevated above 40 ng/ml. The results obtained are as follows: In 44 cases of total 212 patients, abnormal AFP levels above 40 ng/ml in serum were measured; 24 of 31 patients with primary hepatocellular carcinoma and primary hepatocellular carcinoma with liver cirrhosis (77.4%), 7 of 51 patients with only liver cirrhosis (13.7%), 4 of 10 patients with metastatic liver cancer (40.0%), 4 of 15 patients with chronic hepatitis (26.7%), 2 of 23 patients with acute hepatitis (8.7%), and each one patient with 6 pancreatic carcinoma and 9 cholangiocarcinoma had elevated serum AFP levels. One pregnant woman with gestation 35 weeks had elevated level, but within normal limit during pregnancy.}
journal = {Journal of the Korean Radiological Society}
issue = {2}
volume = {18}
place = {Korea, Republic of}
year = {1982}
month = {Jun}
}