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Micro RNAs as molecular markers of glioblastoma multiform

Abstract

The aim of this project was to unravel the role that miR-221 and miR-222, of which we had already demonstrated the specific differential expression in glioblastoma multiforme compared to normal brain, play in the control of cell proliferation, with the ultimate goal to provide new insights in the molecular basis of cancer. The results of our research allowed to identify an important molecular target for miRNA-221 and miR-222, highly expressed in glioblastoma multiforme tissues and cell lines, and to precisely recognize the mRNA regions responsible for this regulation.
Authors:
Farace, M G; [1]  Finocchiaro, G; [2]  Ricci Vitiani, L [3] 
  1. Department Experimental Medicine and Biochemical Sciences, University of Tor Vergata, Rome (Italy)
  2. Istituto Neurologico Besta, Milan (Italy)
  3. Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanita, Rome (Italy)
Publication Date:
Jul 01, 2009
Product Type:
Technical Report
Report Number:
ISTISAN-09-5
Resource Relation:
Related Information: In: ISS-NIH Collaborative Programme: final report of the projects, Programma di collaborazione ISS-NIH: relazioni conclusive dei progetti, 467 pages.
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ANIMAL CELLS; BRAIN; GLIOMAS; IN VIVO; MEDICINE; NEOPLASMS; RNA
OSTI ID:
21195408
Research Organizations:
Istituto Superiore di Sanita (Italy)
Country of Origin:
Italy
Language:
English
Other Identifying Numbers:
Other: ISSN 1123-3117; TRN: IT0900373067974
Availability:
Available from INIS in electronic form; Also available from http://www.iss.it
Submitting Site:
INIS
Size:
page(s) 275-277
Announcement Date:
Aug 19, 2009

Citation Formats

Farace, M G, Finocchiaro, G, and Ricci Vitiani, L. Micro RNAs as molecular markers of glioblastoma multiform. Italy: N. p., 2009. Web.
Farace, M G, Finocchiaro, G, & Ricci Vitiani, L. Micro RNAs as molecular markers of glioblastoma multiform. Italy.
Farace, M G, Finocchiaro, G, and Ricci Vitiani, L. 2009. "Micro RNAs as molecular markers of glioblastoma multiform." Italy.
@misc{etde_21195408,
title = {Micro RNAs as molecular markers of glioblastoma multiform}
author = {Farace, M G, Finocchiaro, G, and Ricci Vitiani, L}
abstractNote = {The aim of this project was to unravel the role that miR-221 and miR-222, of which we had already demonstrated the specific differential expression in glioblastoma multiforme compared to normal brain, play in the control of cell proliferation, with the ultimate goal to provide new insights in the molecular basis of cancer. The results of our research allowed to identify an important molecular target for miRNA-221 and miR-222, highly expressed in glioblastoma multiforme tissues and cell lines, and to precisely recognize the mRNA regions responsible for this regulation.}
place = {Italy}
year = {2009}
month = {Jul}
}