Abstract
Objective: To observe the changes of renal function during simple coronary angiography (CAG)and pereutaneous coronary intervention (PCI)caused by low osmolar non-ionic contrast media and to evaluate the preventive effect of losartan on renal function(serum creatinine)in PCI. Methods: All 171 cases were divided into 3 groups, CAG negative group(N=73), PCI group (N=52)and treatment group (PCI + Losartan, N=46)according to the results given by coronary arteriography. The investigation was performed on the influences produced by the low osmolar non-ionic contrast medium(Ioversol)on renal function and minimal albumin proteinuria in the 3 groups. The minimal albumin proteinuria and renal function (serum creatinine) were tested before and 1 d, 3 d, 7 d after the procedure and followed by the comparison and evaluation of the outcoming data. Results: There were no significant changes of serum creatinine among 3 groups, but amount of minimal albumin proteinuria was increased in PCI group (P<0.05), and decreased obviously after Losartan medication (P<0.05). Conclusion: Low ormolar non-ionic contrast media produce no significant influence on renal function (serum creatinine)during CAG and/or PCI but with different degrees of increase for minimal albumin proteinuria, especially in PCI group. Losartan can decrease minimal albumin proteinuria after PCI procedure, possibly providing the prevention for contrast
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Yueguang, Chen;
Dadong, Zhang;
Jun, Gu;
Zhiping, Song;
Qiang, Yu;
Xiaodi, Feng;
Hongbing, Xiao;
Guizhi, Yin;
Ping, Guan;
Chengjun, Chen;
Hui, Yang;
Xian, Jin;
Jian, Dong;
Xiaomin, Fan
[1]
- Department of Cardiology, Shanghai Minhang Central Hospital, Shanghai (China)
Citation Formats
Yueguang, Chen, Dadong, Zhang, Jun, Gu, Zhiping, Song, Qiang, Yu, Xiaodi, Feng, Hongbing, Xiao, Guizhi, Yin, Ping, Guan, Chengjun, Chen, Hui, Yang, Xian, Jin, Jian, Dong, and Xiaomin, Fan.
Protective effects of losartan in renal dysfunction during coronary angiography and intervention caused by low osmolar non-ionic contrast media.
China: N. p.,
2007.
Web.
Yueguang, Chen, Dadong, Zhang, Jun, Gu, Zhiping, Song, Qiang, Yu, Xiaodi, Feng, Hongbing, Xiao, Guizhi, Yin, Ping, Guan, Chengjun, Chen, Hui, Yang, Xian, Jin, Jian, Dong, & Xiaomin, Fan.
Protective effects of losartan in renal dysfunction during coronary angiography and intervention caused by low osmolar non-ionic contrast media.
China.
Yueguang, Chen, Dadong, Zhang, Jun, Gu, Zhiping, Song, Qiang, Yu, Xiaodi, Feng, Hongbing, Xiao, Guizhi, Yin, Ping, Guan, Chengjun, Chen, Hui, Yang, Xian, Jin, Jian, Dong, and Xiaomin, Fan.
2007.
"Protective effects of losartan in renal dysfunction during coronary angiography and intervention caused by low osmolar non-ionic contrast media."
China.
@misc{etde_21170002,
title = {Protective effects of losartan in renal dysfunction during coronary angiography and intervention caused by low osmolar non-ionic contrast media}
author = {Yueguang, Chen, Dadong, Zhang, Jun, Gu, Zhiping, Song, Qiang, Yu, Xiaodi, Feng, Hongbing, Xiao, Guizhi, Yin, Ping, Guan, Chengjun, Chen, Hui, Yang, Xian, Jin, Jian, Dong, and Xiaomin, Fan}
abstractNote = {Objective: To observe the changes of renal function during simple coronary angiography (CAG)and pereutaneous coronary intervention (PCI)caused by low osmolar non-ionic contrast media and to evaluate the preventive effect of losartan on renal function(serum creatinine)in PCI. Methods: All 171 cases were divided into 3 groups, CAG negative group(N=73), PCI group (N=52)and treatment group (PCI + Losartan, N=46)according to the results given by coronary arteriography. The investigation was performed on the influences produced by the low osmolar non-ionic contrast medium(Ioversol)on renal function and minimal albumin proteinuria in the 3 groups. The minimal albumin proteinuria and renal function (serum creatinine) were tested before and 1 d, 3 d, 7 d after the procedure and followed by the comparison and evaluation of the outcoming data. Results: There were no significant changes of serum creatinine among 3 groups, but amount of minimal albumin proteinuria was increased in PCI group (P<0.05), and decreased obviously after Losartan medication (P<0.05). Conclusion: Low ormolar non-ionic contrast media produce no significant influence on renal function (serum creatinine)during CAG and/or PCI but with different degrees of increase for minimal albumin proteinuria, especially in PCI group. Losartan can decrease minimal albumin proteinuria after PCI procedure, possibly providing the prevention for contrast medium induced nephropathy. (authors)}
journal = []
issue = {11}
volume = {16}
place = {China}
year = {2007}
month = {Nov}
}
title = {Protective effects of losartan in renal dysfunction during coronary angiography and intervention caused by low osmolar non-ionic contrast media}
author = {Yueguang, Chen, Dadong, Zhang, Jun, Gu, Zhiping, Song, Qiang, Yu, Xiaodi, Feng, Hongbing, Xiao, Guizhi, Yin, Ping, Guan, Chengjun, Chen, Hui, Yang, Xian, Jin, Jian, Dong, and Xiaomin, Fan}
abstractNote = {Objective: To observe the changes of renal function during simple coronary angiography (CAG)and pereutaneous coronary intervention (PCI)caused by low osmolar non-ionic contrast media and to evaluate the preventive effect of losartan on renal function(serum creatinine)in PCI. Methods: All 171 cases were divided into 3 groups, CAG negative group(N=73), PCI group (N=52)and treatment group (PCI + Losartan, N=46)according to the results given by coronary arteriography. The investigation was performed on the influences produced by the low osmolar non-ionic contrast medium(Ioversol)on renal function and minimal albumin proteinuria in the 3 groups. The minimal albumin proteinuria and renal function (serum creatinine) were tested before and 1 d, 3 d, 7 d after the procedure and followed by the comparison and evaluation of the outcoming data. Results: There were no significant changes of serum creatinine among 3 groups, but amount of minimal albumin proteinuria was increased in PCI group (P<0.05), and decreased obviously after Losartan medication (P<0.05). Conclusion: Low ormolar non-ionic contrast media produce no significant influence on renal function (serum creatinine)during CAG and/or PCI but with different degrees of increase for minimal albumin proteinuria, especially in PCI group. Losartan can decrease minimal albumin proteinuria after PCI procedure, possibly providing the prevention for contrast medium induced nephropathy. (authors)}
journal = []
issue = {11}
volume = {16}
place = {China}
year = {2007}
month = {Nov}
}