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Dosimetry for synchrotron stereotactic radiotherapy: Monte Carlo simulations and radiosensitive gels; Dosimetrie pour la radiotherapie stereotaxique en rayonnement synchrotron: calculs Monte-Carlo et gels radiosensibles

Abstract

High grade gliomas are extremely aggressive brain tumours. Specific techniques combining the presence of high atomic number elements within the tumour to an irradiation with a low x-rays (below 100 keV) beam from a synchrotron source were proposed. For the sake of clinical trials, the use of treatment planning system has to be foreseen as well as tailored dosimetry protocols. Objectives of this thesis work were (1) the development of a dose calculation tools based on Monte Carlo code for particles transport and (2) the implementation of an experimental method for the three dimensional verification of the dose delivered. The dosimetric tool is an interface between tomography images from patient or sample and the M.C.N.P.X. general purpose code. Besides, dose distributions were measured through a radiosensitive polymer gel, providing acceptable results compared to calculations.
Authors:
Publication Date:
Sep 15, 2006
Product Type:
Thesis/Dissertation
Report Number:
FRNC-TH-7101
Resource Relation:
Other Information: TH: These physique pour l'instrumentation; Also available from Bibliotheque Universitaire de Sciences de Grenoble, 430, avenue de la Bibliotheque, BP66 Domaine Universitaire, 38402 - Saint-Martin d'Heres cedex (France)
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; BRAIN; DOSIMETRY; GELS; GLIOMAS; MONTE CARLO METHOD; NUCLEAR MAGNETIC RESONANCE; POLYMERS; RADIOSENSITIVITY; RADIOTHERAPY; SYNCHROTRON RADIATION; TOMOGRAPHY; X RADIATION
OSTI ID:
21112692
Research Organizations:
Grenoble-1 Univ. Joseph Fourier, 38 (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR0800223120220
Availability:
Available from INIS in electronic form
Submitting Site:
FRN
Size:
190 pages
Announcement Date:
Dec 19, 2008

Citation Formats

Boudou, C. Dosimetry for synchrotron stereotactic radiotherapy: Monte Carlo simulations and radiosensitive gels; Dosimetrie pour la radiotherapie stereotaxique en rayonnement synchrotron: calculs Monte-Carlo et gels radiosensibles. France: N. p., 2006. Web.
Boudou, C. Dosimetry for synchrotron stereotactic radiotherapy: Monte Carlo simulations and radiosensitive gels; Dosimetrie pour la radiotherapie stereotaxique en rayonnement synchrotron: calculs Monte-Carlo et gels radiosensibles. France.
Boudou, C. 2006. "Dosimetry for synchrotron stereotactic radiotherapy: Monte Carlo simulations and radiosensitive gels; Dosimetrie pour la radiotherapie stereotaxique en rayonnement synchrotron: calculs Monte-Carlo et gels radiosensibles." France.
@misc{etde_21112692,
title = {Dosimetry for synchrotron stereotactic radiotherapy: Monte Carlo simulations and radiosensitive gels; Dosimetrie pour la radiotherapie stereotaxique en rayonnement synchrotron: calculs Monte-Carlo et gels radiosensibles}
author = {Boudou, C}
abstractNote = {High grade gliomas are extremely aggressive brain tumours. Specific techniques combining the presence of high atomic number elements within the tumour to an irradiation with a low x-rays (below 100 keV) beam from a synchrotron source were proposed. For the sake of clinical trials, the use of treatment planning system has to be foreseen as well as tailored dosimetry protocols. Objectives of this thesis work were (1) the development of a dose calculation tools based on Monte Carlo code for particles transport and (2) the implementation of an experimental method for the three dimensional verification of the dose delivered. The dosimetric tool is an interface between tomography images from patient or sample and the M.C.N.P.X. general purpose code. Besides, dose distributions were measured through a radiosensitive polymer gel, providing acceptable results compared to calculations.}
place = {France}
year = {2006}
month = {Sep}
}