Abstract
Seven patients with thrombotic occlusions of the peripheral arteries or grafts were treated with urokinase by direct intraarterial selective infusion. During the infusion, simultaneous heparin infusion was used to reduce the frequency of thrombus formation on the infusion catheter or recurrent thrombosis. In 4 patients in whom a complete thrombolysis occurred, urokinase was infused by a high-dose transthrombus bolus technique followed by continuous infusion. There other patients, in whom thrombolysis was partially accomplished and then surgical thrombectomy was performed, were treated only by continuous urokinase infusion. Small hematomas developed at the infusion catheter entry site in 2 patients, but transfusion or operation was not required. Other significant complications were not found. Our results suggest that selective arterial infusion of urokinase with a transthrombus bolus technique can accomplish a complete arterial thrombolysis without any significant complications.
Park, Jae Hyung;
Park, Kil Sun;
Chung, Jin Wook;
Han, Joon Koo;
Kim, Sang Joon;
[1]
Kim, Dae Young
[2]
- Seoul National University College of Medicine, Seoul (Korea, Republic of)
- Choong Buk University College of Medicine, Jeonju (Korea, Republic of)
Citation Formats
Park, Jae Hyung, Park, Kil Sun, Chung, Jin Wook, Han, Joon Koo, Kim, Sang Joon, and Kim, Dae Young.
Selective arterial thrombolysis with urokinase.
Korea, Republic of: N. p.,
1991.
Web.
Park, Jae Hyung, Park, Kil Sun, Chung, Jin Wook, Han, Joon Koo, Kim, Sang Joon, & Kim, Dae Young.
Selective arterial thrombolysis with urokinase.
Korea, Republic of.
Park, Jae Hyung, Park, Kil Sun, Chung, Jin Wook, Han, Joon Koo, Kim, Sang Joon, and Kim, Dae Young.
1991.
"Selective arterial thrombolysis with urokinase."
Korea, Republic of.
@misc{etde_21111926,
title = {Selective arterial thrombolysis with urokinase}
author = {Park, Jae Hyung, Park, Kil Sun, Chung, Jin Wook, Han, Joon Koo, Kim, Sang Joon, and Kim, Dae Young}
abstractNote = {Seven patients with thrombotic occlusions of the peripheral arteries or grafts were treated with urokinase by direct intraarterial selective infusion. During the infusion, simultaneous heparin infusion was used to reduce the frequency of thrombus formation on the infusion catheter or recurrent thrombosis. In 4 patients in whom a complete thrombolysis occurred, urokinase was infused by a high-dose transthrombus bolus technique followed by continuous infusion. There other patients, in whom thrombolysis was partially accomplished and then surgical thrombectomy was performed, were treated only by continuous urokinase infusion. Small hematomas developed at the infusion catheter entry site in 2 patients, but transfusion or operation was not required. Other significant complications were not found. Our results suggest that selective arterial infusion of urokinase with a transthrombus bolus technique can accomplish a complete arterial thrombolysis without any significant complications.}
journal = []
issue = {4}
volume = {27}
place = {Korea, Republic of}
year = {1991}
month = {Jul}
}
title = {Selective arterial thrombolysis with urokinase}
author = {Park, Jae Hyung, Park, Kil Sun, Chung, Jin Wook, Han, Joon Koo, Kim, Sang Joon, and Kim, Dae Young}
abstractNote = {Seven patients with thrombotic occlusions of the peripheral arteries or grafts were treated with urokinase by direct intraarterial selective infusion. During the infusion, simultaneous heparin infusion was used to reduce the frequency of thrombus formation on the infusion catheter or recurrent thrombosis. In 4 patients in whom a complete thrombolysis occurred, urokinase was infused by a high-dose transthrombus bolus technique followed by continuous infusion. There other patients, in whom thrombolysis was partially accomplished and then surgical thrombectomy was performed, were treated only by continuous urokinase infusion. Small hematomas developed at the infusion catheter entry site in 2 patients, but transfusion or operation was not required. Other significant complications were not found. Our results suggest that selective arterial infusion of urokinase with a transthrombus bolus technique can accomplish a complete arterial thrombolysis without any significant complications.}
journal = []
issue = {4}
volume = {27}
place = {Korea, Republic of}
year = {1991}
month = {Jul}
}