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An experimental study on the influence of the intravascular gianturco type stents on the vascular structures

Abstract

Twenty-seven Gianturco-type self-expandable stainless steel intravascular stents were placed into the infrarenal abdominal aortas (n=17) and inferior venae cavae (n=10) in 14 mongrel dogs. In 8 aortas, stents were delivered after balloon catheter-induced denudation of the intima, and in 4 out of the 8 aortas, the stents were also placed into the normal sites to compare the neointimal thickness of the normal and denuded sites. Angiography, light microscopic, and scanning electron microscopic examinations were performed after 1 week (n=1), 2 weeks (n=6), 3 weeks (n=5), and 6 weeks (n=2). The patency rate and thrombosis rate were 100% and 35% in the aortas and 100% and 60% in the inferior venae cavae. The aortic stent wires were covered with thin fibrinous membrane after 1 week. Nearly complete transparent neointimal covering was found in the aortas and caval veins after 2 weeks. There was no significant difference in intimal thickness between the denuded and normal aortas after 2 weeks ({rho} =0.51) and 3 weeks ({rho} =0.56). In 4 dogs with caval vein stents, there was evidence of hemorrhage infarction in the lungs. The thrombosis rate of 12 stents with a stent-artery ratio (SAR) of 1.5 or higher was 41%, while there was  More>>
Authors:
Choe, Yeon Hyeon; [1]  Park, Jae Hyung; Han, Joon Koo; Han, Man Chung; Kim, Chu Wan [2] 
  1. Sejong General Hospital, Bucheon (Korea, Republic of)
  2. College of Medicine, Seoul National University, Seoul (Korea, Republic of)
Publication Date:
Jul 15, 1991
Product Type:
Journal Article
Resource Relation:
Journal Name: Journal of the Korean Radiological Society; Journal Volume: 27; Journal Issue: 4; Other Information: 30 refs, 7 figs, 3 tabs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; AORTA; BIOMEDICAL RADIOGRAPHY; BLOOD FLOW; DOGS; HEMORRHAGE; LUNGS; PROSTHESES; THROMBOSIS; VASCULAR DISEASES
OSTI ID:
21111925
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 1738-2637; DBSHAH; TRN: KR0803440119425
Submitting Site:
KRN
Size:
page(s) 431-439
Announcement Date:
Dec 19, 2008

Citation Formats

Choe, Yeon Hyeon, Park, Jae Hyung, Han, Joon Koo, Han, Man Chung, and Kim, Chu Wan. An experimental study on the influence of the intravascular gianturco type stents on the vascular structures. Korea, Republic of: N. p., 1991. Web.
Choe, Yeon Hyeon, Park, Jae Hyung, Han, Joon Koo, Han, Man Chung, & Kim, Chu Wan. An experimental study on the influence of the intravascular gianturco type stents on the vascular structures. Korea, Republic of.
Choe, Yeon Hyeon, Park, Jae Hyung, Han, Joon Koo, Han, Man Chung, and Kim, Chu Wan. 1991. "An experimental study on the influence of the intravascular gianturco type stents on the vascular structures." Korea, Republic of.
@misc{etde_21111925,
title = {An experimental study on the influence of the intravascular gianturco type stents on the vascular structures}
author = {Choe, Yeon Hyeon, Park, Jae Hyung, Han, Joon Koo, Han, Man Chung, and Kim, Chu Wan}
abstractNote = {Twenty-seven Gianturco-type self-expandable stainless steel intravascular stents were placed into the infrarenal abdominal aortas (n=17) and inferior venae cavae (n=10) in 14 mongrel dogs. In 8 aortas, stents were delivered after balloon catheter-induced denudation of the intima, and in 4 out of the 8 aortas, the stents were also placed into the normal sites to compare the neointimal thickness of the normal and denuded sites. Angiography, light microscopic, and scanning electron microscopic examinations were performed after 1 week (n=1), 2 weeks (n=6), 3 weeks (n=5), and 6 weeks (n=2). The patency rate and thrombosis rate were 100% and 35% in the aortas and 100% and 60% in the inferior venae cavae. The aortic stent wires were covered with thin fibrinous membrane after 1 week. Nearly complete transparent neointimal covering was found in the aortas and caval veins after 2 weeks. There was no significant difference in intimal thickness between the denuded and normal aortas after 2 weeks ({rho} =0.51) and 3 weeks ({rho} =0.56). In 4 dogs with caval vein stents, there was evidence of hemorrhage infarction in the lungs. The thrombosis rate of 12 stents with a stent-artery ratio (SAR) of 1.5 or higher was 41%, while there was no thrombus on the 4 stents with SAR 1.2 or lower, except for 1 specimen after 1 week. It is suggested that stents with SAR 1.2 or lower are more suitable. The high thrombosis rate of the inferior venae cavae may be related with slow blood flow.}
journal = []
issue = {4}
volume = {27}
place = {Korea, Republic of}
year = {1991}
month = {Jul}
}