You need JavaScript to view this

Transcatheter closure of patent ductus arteriosus with severe pulmonary arterial hypertension in adults

Journal Article:

Abstract

Objective: To evaluate the effect of self-expandable occluder on closure of patent ductus arteriosus (PDA) with severe pulmonary arterial hypertension (PH) in adults. Methods: Twenty-eight adult patients underwent transcatheter closure of PDA at a mean age of (31.3{+-}11.6) years [(18-58) years]. Either Amplatzer duct occluder or domestic device was used in the present study. X-ray, EKG and UCG were repeated in one day, one month, three months, and six months. Results: Twenty of the 28 patients had successful occlusion, and the other 8 patients were given up. In the successful group, the narrowest diameter of PDA was (10.4{+-}2.7) mm [(6-16) mm], the diameter of selected occluder was (15.6{+-}3.2)mm [(10-20) mm] at the end of pulmonary artery. Systemic artery oxygen saturation (SAsat) before and after oxygen inhalation was (93.5{+-}1.8)%, (98.2{+-}1.8)%, respectively (P<0.01). Systolic pulmonary arterial pressure decreased significantly after trial occlusion from (95.5{+-} 24.l) mm Hg to (56.3{+-}18.3) mm Hg (P<0.01); Mean pulmonary arterial pressures decreased significantly from (70.8{+-}18.2) mm Hg to (41.0{+-}13.8 )mm Hg (P<0. 01), too. Six months later UCG showed that the dimensions of left atrium, left ventricle and pulmonary artery attenuated significantly with one exception; X rays showed decreased pulmonary vascularity or cardiac size as well [cardio-thoracic  More>>
Authors:
Shihua, Zhao; Chaowu, Yan; Shiliang, Jiang; Zhongying, Xu; Lianjun, Huang; Jian, Ling; Hong, Zheng; Cheng, Wang; Haibo, Hu; Wenhui, Wu; Shiguo, Li; Ruping, Dai [1] 
  1. Department of Radiology, Cardiovascular Inst. and Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing Union Medical College, Beijing (China)
Publication Date:
Nov 15, 2006
Product Type:
Journal Article
Resource Relation:
Journal Name: Chinese Journal of Radiology; Journal Volume: 40; Journal Issue: 11; Other Information: 2 tabs., 9 refs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ADULTS; ARTERIES; BIOMEDICAL RADIOGRAPHY; CARDIOGRAPHY; DIAGNOSIS; EFFICIENCY; ELECTROCARDIOGRAMS; HYPERTENSION; LUNGS; OXYGEN; PATIENTS; SATURATION; THERAPY; ULTRASONOGRAPHY; X RADIATION
OSTI ID:
21101193
Country of Origin:
China
Language:
Chinese
Other Identifying Numbers:
Journal ID: ISSN 1005-1201; CHFSAG; TRN: CN0802963111288
Submitting Site:
INIS
Size:
page(s) 1185-1189
Announcement Date:
Dec 12, 2008

Journal Article:

Citation Formats

Shihua, Zhao, Chaowu, Yan, Shiliang, Jiang, Zhongying, Xu, Lianjun, Huang, Jian, Ling, Hong, Zheng, Cheng, Wang, Haibo, Hu, Wenhui, Wu, Shiguo, Li, and Ruping, Dai. Transcatheter closure of patent ductus arteriosus with severe pulmonary arterial hypertension in adults. China: N. p., 2006. Web.
Shihua, Zhao, Chaowu, Yan, Shiliang, Jiang, Zhongying, Xu, Lianjun, Huang, Jian, Ling, Hong, Zheng, Cheng, Wang, Haibo, Hu, Wenhui, Wu, Shiguo, Li, & Ruping, Dai. Transcatheter closure of patent ductus arteriosus with severe pulmonary arterial hypertension in adults. China.
Shihua, Zhao, Chaowu, Yan, Shiliang, Jiang, Zhongying, Xu, Lianjun, Huang, Jian, Ling, Hong, Zheng, Cheng, Wang, Haibo, Hu, Wenhui, Wu, Shiguo, Li, and Ruping, Dai. 2006. "Transcatheter closure of patent ductus arteriosus with severe pulmonary arterial hypertension in adults." China.
@misc{etde_21101193,
title = {Transcatheter closure of patent ductus arteriosus with severe pulmonary arterial hypertension in adults}
author = {Shihua, Zhao, Chaowu, Yan, Shiliang, Jiang, Zhongying, Xu, Lianjun, Huang, Jian, Ling, Hong, Zheng, Cheng, Wang, Haibo, Hu, Wenhui, Wu, Shiguo, Li, and Ruping, Dai}
abstractNote = {Objective: To evaluate the effect of self-expandable occluder on closure of patent ductus arteriosus (PDA) with severe pulmonary arterial hypertension (PH) in adults. Methods: Twenty-eight adult patients underwent transcatheter closure of PDA at a mean age of (31.3{+-}11.6) years [(18-58) years]. Either Amplatzer duct occluder or domestic device was used in the present study. X-ray, EKG and UCG were repeated in one day, one month, three months, and six months. Results: Twenty of the 28 patients had successful occlusion, and the other 8 patients were given up. In the successful group, the narrowest diameter of PDA was (10.4{+-}2.7) mm [(6-16) mm], the diameter of selected occluder was (15.6{+-}3.2)mm [(10-20) mm] at the end of pulmonary artery. Systemic artery oxygen saturation (SAsat) before and after oxygen inhalation was (93.5{+-}1.8)%, (98.2{+-}1.8)%, respectively (P<0.01). Systolic pulmonary arterial pressure decreased significantly after trial occlusion from (95.5{+-} 24.l) mm Hg to (56.3{+-}18.3) mm Hg (P<0.01); Mean pulmonary arterial pressures decreased significantly from (70.8{+-}18.2) mm Hg to (41.0{+-}13.8 )mm Hg (P<0. 01), too. Six months later UCG showed that the dimensions of left atrium, left ventricle and pulmonary artery attenuated significantly with one exception; X rays showed decreased pulmonary vascularity or cardiac size as well [cardio-thoracic ratio: (59.2{+-}6.6)% vs (54.2{+-}3.3)%, P<0.01]. In given up group, four patients were defined as Eisenmenger syndromes with differential cyanosis. They presented with elevated systolic pulmonary arterial pressure [(110.3{+-}13.9) mm Hg vs (139.5{+-}20.0)mm Hg, P<0.01], or decreased systolic aortic pressure[(116.0{+-}20.2)mm Hg vs (106.3{+-}16.9) mm Hg, P<0.05]after occlusion. The others included two cases with large residual shunt, and two cases with worsening of symptoms. Conclusions: Transcatheter closure of PDA with reversible severe PH is feasible, effective and safe in adults. (authors)}
journal = {Chinese Journal of Radiology}
issue = {11}
volume = {40}
place = {China}
year = {2006}
month = {Nov}
}