Abstract
After an intake of radioactive material, its behaviour in the human body can be described by mathematical models, where organs, tissues or regions of the body are treated as a chain of linked compartments. The mathematical approach for such metabolic models is usually done through a system of differential equations of first order with constant coefficients. The solutions of this system of equations associates the radionuclide intake, with the fraction excreted or retained in the organ of interest. A computer program - called INCORP and for running in PC compatible microcomputers - was developed in order to find the solutions of such system of equations, using an analytical method based on expansion of series of exponential matrices. The metabolic model presented in the ICRP-30 publication was simulated using the INCORP program, in order to find the respective retention and excretion curves for selected radionuclides. (author)
Citation Formats
Rodrigues, Junior, O.
Application of compartmental metabolic models for determination of retention and excretion functions; Aplicacao de modelos metabolicos para a determinacao de funcoes de excrecao e retencao.
Brazil: N. p.,
1994.
Web.
Rodrigues, Junior, O.
Application of compartmental metabolic models for determination of retention and excretion functions; Aplicacao de modelos metabolicos para a determinacao de funcoes de excrecao e retencao.
Brazil.
Rodrigues, Junior, O.
1994.
"Application of compartmental metabolic models for determination of retention and excretion functions; Aplicacao de modelos metabolicos para a determinacao de funcoes de excrecao e retencao."
Brazil.
@misc{etde_21100397,
title = {Application of compartmental metabolic models for determination of retention and excretion functions; Aplicacao de modelos metabolicos para a determinacao de funcoes de excrecao e retencao}
author = {Rodrigues, Junior, O}
abstractNote = {After an intake of radioactive material, its behaviour in the human body can be described by mathematical models, where organs, tissues or regions of the body are treated as a chain of linked compartments. The mathematical approach for such metabolic models is usually done through a system of differential equations of first order with constant coefficients. The solutions of this system of equations associates the radionuclide intake, with the fraction excreted or retained in the organ of interest. A computer program - called INCORP and for running in PC compatible microcomputers - was developed in order to find the solutions of such system of equations, using an analytical method based on expansion of series of exponential matrices. The metabolic model presented in the ICRP-30 publication was simulated using the INCORP program, in order to find the respective retention and excretion curves for selected radionuclides. (author)}
place = {Brazil}
year = {1994}
month = {Jul}
}
title = {Application of compartmental metabolic models for determination of retention and excretion functions; Aplicacao de modelos metabolicos para a determinacao de funcoes de excrecao e retencao}
author = {Rodrigues, Junior, O}
abstractNote = {After an intake of radioactive material, its behaviour in the human body can be described by mathematical models, where organs, tissues or regions of the body are treated as a chain of linked compartments. The mathematical approach for such metabolic models is usually done through a system of differential equations of first order with constant coefficients. The solutions of this system of equations associates the radionuclide intake, with the fraction excreted or retained in the organ of interest. A computer program - called INCORP and for running in PC compatible microcomputers - was developed in order to find the solutions of such system of equations, using an analytical method based on expansion of series of exponential matrices. The metabolic model presented in the ICRP-30 publication was simulated using the INCORP program, in order to find the respective retention and excretion curves for selected radionuclides. (author)}
place = {Brazil}
year = {1994}
month = {Jul}
}