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Carotid artery wall thickness and ischemic symptoms: evaluation using multi-detector-row CT angiography

Abstract

The purpose of this study was to determine if carotid artery wall thickness (CAWT) studied by using multi-detector-row CT angiography (MDCTA) can be considered an effective parameter predictive of increased risk of stroke. A total of 217 patients were retrospectively studied by using MDCTA. In all patients CAWT was measured with an internal digital caliper. Continuous data were described as the mean value {+-} standard deviation (SD), and they were compared with Student's t-test. Scatter plots to determine interobserver agreement were performed, and correlation coefficient was calculated with Pearson statistics. A P value <0.05 was considered to mean statistical significance. Measurements of the distal common CAWT ranged from 0.5 to 1.6 mm. In the patient group without stroke, average CAWT was 0.82 mm (0.22 SD), whereas in patient group with stroke it was 1.096 mm (0.21 SD). CAWT in patients without stroke showed statistical difference (P<0.0001) when compared to patients with stroke. By using a threshold of 1 mm, an important statistical association between thick CAWT and stroke was found (P<0.0001). In fact, patients with {>=}1 mm CAWT had stroke with an odds ratio of 8.16 when compared with patients with <1 mm CAWT. Resulting data suggested that an increased  More>>
Authors:
Saba, Luca; Caddeo, Giancarlo; Mallarini, Giorgio; [1]  Sanfilippo, Roberto; Montisci, Roberto; [2]  Pascalis, Luigi [3] 
  1. Azienda Ospedaliero Universitaria Polo di Monserrato, Department of Radiology, Cagliari (Italy)
  2. Azienda Ospedaliero Universitaria Polo di Monserrato, Department of Vascular Surgery, Cagliari (Italy)
  3. Azienda Ospedaliero Universitaria Polo di Cagliari, Division of II Internal Medicine, Cagliari (Italy)
Publication Date:
Sep 15, 2008
Product Type:
Journal Article
Resource Relation:
Journal Name: European Radiology; Journal Volume: 18; Journal Issue: 9
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CAROTID ARTERIES; COMPUTERIZED TOMOGRAPHY; ISCHEMIA
OSTI ID:
21085616
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0938-7994; EURAE3; TRN: DE08FA745
Availability:
Available from: http://dx.doi.org/10.1007/s00330-008-0962-5
Submitting Site:
DEN
Size:
page(s) 1962-1971
Announcement Date:
Nov 03, 2008

Citation Formats

Saba, Luca, Caddeo, Giancarlo, Mallarini, Giorgio, Sanfilippo, Roberto, Montisci, Roberto, and Pascalis, Luigi. Carotid artery wall thickness and ischemic symptoms: evaluation using multi-detector-row CT angiography. Germany: N. p., 2008. Web. doi:10.1007/S00330-008-0962-5.
Saba, Luca, Caddeo, Giancarlo, Mallarini, Giorgio, Sanfilippo, Roberto, Montisci, Roberto, & Pascalis, Luigi. Carotid artery wall thickness and ischemic symptoms: evaluation using multi-detector-row CT angiography. Germany. doi:10.1007/S00330-008-0962-5.
Saba, Luca, Caddeo, Giancarlo, Mallarini, Giorgio, Sanfilippo, Roberto, Montisci, Roberto, and Pascalis, Luigi. 2008. "Carotid artery wall thickness and ischemic symptoms: evaluation using multi-detector-row CT angiography." Germany. doi:10.1007/S00330-008-0962-5. https://www.osti.gov/servlets/purl/10.1007/S00330-008-0962-5.
@misc{etde_21085616,
title = {Carotid artery wall thickness and ischemic symptoms: evaluation using multi-detector-row CT angiography}
author = {Saba, Luca, Caddeo, Giancarlo, Mallarini, Giorgio, Sanfilippo, Roberto, Montisci, Roberto, and Pascalis, Luigi}
abstractNote = {The purpose of this study was to determine if carotid artery wall thickness (CAWT) studied by using multi-detector-row CT angiography (MDCTA) can be considered an effective parameter predictive of increased risk of stroke. A total of 217 patients were retrospectively studied by using MDCTA. In all patients CAWT was measured with an internal digital caliper. Continuous data were described as the mean value {+-} standard deviation (SD), and they were compared with Student's t-test. Scatter plots to determine interobserver agreement were performed, and correlation coefficient was calculated with Pearson statistics. A P value <0.05 was considered to mean statistical significance. Measurements of the distal common CAWT ranged from 0.5 to 1.6 mm. In the patient group without stroke, average CAWT was 0.82 mm (0.22 SD), whereas in patient group with stroke it was 1.096 mm (0.21 SD). CAWT in patients without stroke showed statistical difference (P<0.0001) when compared to patients with stroke. By using a threshold of 1 mm, an important statistical association between thick CAWT and stroke was found (P<0.0001). In fact, patients with {>=}1 mm CAWT had stroke with an odds ratio of 8.16 when compared with patients with <1 mm CAWT. Resulting data suggested that an increased CAWT is an indicator for risk of stroke. This parameter should be considered in addition to other well-known risk factors such as diabetes, hypertension, smoking, and dyslipidemia. (orig.)}
doi = {10.1007/S00330-008-0962-5}
journal = {European Radiology}
issue = {9}
volume = {18}
place = {Germany}
year = {2008}
month = {Sep}
}