Abstract
Purpose: To examine the feasibility of transvenous placement of a new memory-shaped, small, retrievable coil that has a smaller-caliber delivery system than currently available devices, for closure of the patent ductus arteriosus (PDA). Methods: Through 4 or 5 Fr vascular sheaths and 4 or 5 Fr end-hold catheters, the coils were delivered and placed in piglets (n= 10) with PDA. The coils were made from 0.018'' (0.46 mm) or 0.028'' (0.71 mm) stainless steel guidewire. Mounted for delivery, the new device has the appearance of a conventional guidewire. This neonatal PDA model was created without major surgery or drugs by stenting the ductus arteriosus. Results: The memory-shaped coils were easily delivered. Coils not optimally placed were retrieved and repositioned. Occlusion of the ductus arteriosus as early as a half-hour after delivery was shown angiographically and confirmed by histopathology. Conclusion: This new, small-caliber, simple device was found to be effective for closure of the PDA in this animal model. Longer-term observations are needed.
Neuss, Malte B;
[1]
Coe, James Y;
[2]
Tio, Fermin;
[3]
Le, Trong-Phi;
[1]
Grabitz, Ralph;
[2]
Redel, Dirk A
[1]
- Department of Cardiology, Children's Hospital, University of Bonn, Adenauerallee 119, D-5300, Bonn 1 (Germany)
- Division of Pediatric Cardiology and Cardiovascular Research Group, University of Alberta, Edmonton, Alberta (Canada)
- Department of Pathology, University of Texas Health Sciences Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284-7750 (United States)
Citation Formats
Neuss, Malte B, Coe, James Y, Tio, Fermin, Le, Trong-Phi, Grabitz, Ralph, and Redel, Dirk A.
Occlusion of the Neonatal Patent Ductus Arteriosus with a Simple Retrievable Device: A Feasibility Study.
United States: N. p.,
1996.
Web.
doi:10.1007/S002709900036.
Neuss, Malte B, Coe, James Y, Tio, Fermin, Le, Trong-Phi, Grabitz, Ralph, & Redel, Dirk A.
Occlusion of the Neonatal Patent Ductus Arteriosus with a Simple Retrievable Device: A Feasibility Study.
United States.
https://doi.org/10.1007/S002709900036
Neuss, Malte B, Coe, James Y, Tio, Fermin, Le, Trong-Phi, Grabitz, Ralph, and Redel, Dirk A.
1996.
"Occlusion of the Neonatal Patent Ductus Arteriosus with a Simple Retrievable Device: A Feasibility Study."
United States.
https://doi.org/10.1007/S002709900036.
@misc{etde_21080539,
title = {Occlusion of the Neonatal Patent Ductus Arteriosus with a Simple Retrievable Device: A Feasibility Study}
author = {Neuss, Malte B, Coe, James Y, Tio, Fermin, Le, Trong-Phi, Grabitz, Ralph, and Redel, Dirk A}
abstractNote = {Purpose: To examine the feasibility of transvenous placement of a new memory-shaped, small, retrievable coil that has a smaller-caliber delivery system than currently available devices, for closure of the patent ductus arteriosus (PDA). Methods: Through 4 or 5 Fr vascular sheaths and 4 or 5 Fr end-hold catheters, the coils were delivered and placed in piglets (n= 10) with PDA. The coils were made from 0.018'' (0.46 mm) or 0.028'' (0.71 mm) stainless steel guidewire. Mounted for delivery, the new device has the appearance of a conventional guidewire. This neonatal PDA model was created without major surgery or drugs by stenting the ductus arteriosus. Results: The memory-shaped coils were easily delivered. Coils not optimally placed were retrieved and repositioned. Occlusion of the ductus arteriosus as early as a half-hour after delivery was shown angiographically and confirmed by histopathology. Conclusion: This new, small-caliber, simple device was found to be effective for closure of the PDA in this animal model. Longer-term observations are needed.}
doi = {10.1007/S002709900036}
journal = []
issue = {3}
volume = {19}
place = {United States}
year = {1996}
month = {May}
}
title = {Occlusion of the Neonatal Patent Ductus Arteriosus with a Simple Retrievable Device: A Feasibility Study}
author = {Neuss, Malte B, Coe, James Y, Tio, Fermin, Le, Trong-Phi, Grabitz, Ralph, and Redel, Dirk A}
abstractNote = {Purpose: To examine the feasibility of transvenous placement of a new memory-shaped, small, retrievable coil that has a smaller-caliber delivery system than currently available devices, for closure of the patent ductus arteriosus (PDA). Methods: Through 4 or 5 Fr vascular sheaths and 4 or 5 Fr end-hold catheters, the coils were delivered and placed in piglets (n= 10) with PDA. The coils were made from 0.018'' (0.46 mm) or 0.028'' (0.71 mm) stainless steel guidewire. Mounted for delivery, the new device has the appearance of a conventional guidewire. This neonatal PDA model was created without major surgery or drugs by stenting the ductus arteriosus. Results: The memory-shaped coils were easily delivered. Coils not optimally placed were retrieved and repositioned. Occlusion of the ductus arteriosus as early as a half-hour after delivery was shown angiographically and confirmed by histopathology. Conclusion: This new, small-caliber, simple device was found to be effective for closure of the PDA in this animal model. Longer-term observations are needed.}
doi = {10.1007/S002709900036}
journal = []
issue = {3}
volume = {19}
place = {United States}
year = {1996}
month = {May}
}