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Spontaneous regression of multiple pulmonary metastatic nodules of hepatocarcinoma: a case report

Journal Article:

Abstract

Although are spontaneous regression of either primary or metastatic malignant tumor in the absence of or inadequate therapy has been well documented. Since the earliest day of this century various malignant tumors have been reported to spontaneously disappear or to be arrested of their growth, but the cases of hepatocarcinoma has been very rare. From the literature, we were able to find out 5 previously reported cases of hepatocarcinoma which showed spontaneous regression at the primary site. Recently we have seen a case of multiple pulmonary metastatic nodules of hepatocarcinoma which completely regressed spontaneously and this forms the basis of the present case report. The patient was 55-year-old male admitted to St. Mary's Hospital, Catholic Medical College because of a hard palpable mass in the epigastrium on April 26, 1978. The admission PA chest roentgenogram revealed multiple small nodular densities scattered throughout both lung field especially in lower zones and toward the peripheral portion. A hepatoscintigram revealed a large cold area involving the left lobe and inermediate zone of the liver. Alfa-fetoprotein and hepatitis B serum antigen test were positive whereas many other standard liver function tests turned out to be negative. A needle biopsy of the tumor revealed well  More>>
Authors:
Bahk, Yong Whee; Park, Seog Hee; Kim, Sun Moo [1] 
  1. St. Mary's Hospital, Catholic Medical College, Seoul (Korea, Republic of)
Publication Date:
Sep 15, 1981
Product Type:
Journal Article
Resource Relation:
Journal Name: Journal of the Korean Radiological Society; Journal Volume: 17; Journal Issue: 2; Other Information: 29 refs, 3 figs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; HEPATOMAS; LIVER; METASTASES; PATIENTS; THERAPY
OSTI ID:
21071673
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
Journal ID: ISSN 0301-2867; DBSHAH; TRN: KR0802268085040
Submitting Site:
KRN
Size:
page(s) 269-274
Announcement Date:
Sep 30, 2008

Journal Article:

Citation Formats

Bahk, Yong Whee, Park, Seog Hee, and Kim, Sun Moo. Spontaneous regression of multiple pulmonary metastatic nodules of hepatocarcinoma: a case report. Korea, Republic of: N. p., 1981. Web.
Bahk, Yong Whee, Park, Seog Hee, & Kim, Sun Moo. Spontaneous regression of multiple pulmonary metastatic nodules of hepatocarcinoma: a case report. Korea, Republic of.
Bahk, Yong Whee, Park, Seog Hee, and Kim, Sun Moo. 1981. "Spontaneous regression of multiple pulmonary metastatic nodules of hepatocarcinoma: a case report." Korea, Republic of.
@misc{etde_21071673,
title = {Spontaneous regression of multiple pulmonary metastatic nodules of hepatocarcinoma: a case report}
author = {Bahk, Yong Whee, Park, Seog Hee, and Kim, Sun Moo}
abstractNote = {Although are spontaneous regression of either primary or metastatic malignant tumor in the absence of or inadequate therapy has been well documented. Since the earliest day of this century various malignant tumors have been reported to spontaneously disappear or to be arrested of their growth, but the cases of hepatocarcinoma has been very rare. From the literature, we were able to find out 5 previously reported cases of hepatocarcinoma which showed spontaneous regression at the primary site. Recently we have seen a case of multiple pulmonary metastatic nodules of hepatocarcinoma which completely regressed spontaneously and this forms the basis of the present case report. The patient was 55-year-old male admitted to St. Mary's Hospital, Catholic Medical College because of a hard palpable mass in the epigastrium on April 26, 1978. The admission PA chest roentgenogram revealed multiple small nodular densities scattered throughout both lung field especially in lower zones and toward the peripheral portion. A hepatoscintigram revealed a large cold area involving the left lobe and inermediate zone of the liver. Alfa-fetoprotein and hepatitis B serum antigen test were positive whereas many other standard liver function tests turned out to be negative. A needle biopsy of the tumor revealed well differentiated hepatocellular carcinoma. The patient was put under chemotherapy which consisted of 5 FU 500 mg intravenously for 6 days from April 28 to May 3, 1978. The patient was discharged after this single course of 5 FU treatment and was on a herb medicine, the nature and quantity of which obscure. No other specific treatment was given. The second admission took place on Dec. 3, 1980 because of irregularity in bowel habits and dyspepsia. A follow up PA chest roentgenogram obtained on the second admission revealed complete disappearance of previously noted multiple pulmonary nodular lesions (Fig. 3). Follow up liver scan revealed persistence of the cold area in the left lobe with slight decrease in size. The patient was discharged again without any specific prescription after confirming negative results of various clinical studies including upper GI series and colon study. At the time of finishing this paper the patient is doing well without apparent medical problems.}
journal = {Journal of the Korean Radiological Society}
issue = {2}
volume = {17}
place = {Korea, Republic of}
year = {1981}
month = {Sep}
}