You need JavaScript to view this

Mechanism of Interaction between Ionizing Radiation and Chemicals

Abstract

This research project has been carried out jointly with INP (Poland) to develop technologies for 'Mechanism of Interaction between ionizing radiation and chemicals{sup .} Several biological end-points were assessed in experimental organisms such as higher plants, rats, cell lines and yeast cells to establish proper bioassay techniques. The Tradescantia somatic cell mutation assay was carried out, and immunohistochemistry and hormone assays were done in Fisher 344 rats and cell lines to analyse the combined effect of ionizing radiation with mercury chloride. Using the common regularities of combined actions of two factors, a theoretical model was established, and applied to the thermo radiation action and synergism between two chemicals, as well. The model approach made it possible to predict the condition under which the maximum synergism could be attained. The research results were published in high standard journals and presented in the scientific conferences to verify KAERI's current technology level. The experience of collaboration can be used as a fundamental tool for multinational collaboration, and make the role of improving relationship between Korea and Poland.
Authors:
Kim, Jin Kyu; Lee, B H; Shin, H S [1] 
  1. and others
Publication Date:
Mar 15, 2008
Product Type:
Technical Report
Report Number:
KAERI/RR-2878/2007
Resource Relation:
Other Information: 107 refs, 20 figs, 10 tabs
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; BIOASSAY; DAMAGE; DNA; IMMUNOLOGY; INTERACTIONS; IONIZING RADIATIONS; RADIATION INJURIES; SYNERGISM
OSTI ID:
21068471
Research Organizations:
Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)
Country of Origin:
Korea, Republic of
Language:
Korean
Other Identifying Numbers:
TRN: KR0801592082563
Availability:
Available from INIS in electronic form; Also available from KAERI
Submitting Site:
KRN
Size:
214 pages
Announcement Date:
Sep 15, 2008

Citation Formats

Kim, Jin Kyu, Lee, B H, and Shin, H S. Mechanism of Interaction between Ionizing Radiation and Chemicals. Korea, Republic of: N. p., 2008. Web.
Kim, Jin Kyu, Lee, B H, & Shin, H S. Mechanism of Interaction between Ionizing Radiation and Chemicals. Korea, Republic of.
Kim, Jin Kyu, Lee, B H, and Shin, H S. 2008. "Mechanism of Interaction between Ionizing Radiation and Chemicals." Korea, Republic of.
@misc{etde_21068471,
title = {Mechanism of Interaction between Ionizing Radiation and Chemicals}
author = {Kim, Jin Kyu, Lee, B H, and Shin, H S}
abstractNote = {This research project has been carried out jointly with INP (Poland) to develop technologies for 'Mechanism of Interaction between ionizing radiation and chemicals{sup .} Several biological end-points were assessed in experimental organisms such as higher plants, rats, cell lines and yeast cells to establish proper bioassay techniques. The Tradescantia somatic cell mutation assay was carried out, and immunohistochemistry and hormone assays were done in Fisher 344 rats and cell lines to analyse the combined effect of ionizing radiation with mercury chloride. Using the common regularities of combined actions of two factors, a theoretical model was established, and applied to the thermo radiation action and synergism between two chemicals, as well. The model approach made it possible to predict the condition under which the maximum synergism could be attained. The research results were published in high standard journals and presented in the scientific conferences to verify KAERI's current technology level. The experience of collaboration can be used as a fundamental tool for multinational collaboration, and make the role of improving relationship between Korea and Poland.}
place = {Korea, Republic of}
year = {2008}
month = {Mar}
}