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Radiomimeticity of the system H{sub 2}O{sub 2}/Fe(II) on nucleic acid components. Kinetics study; Radiomimeticidad del sistema H{sub 2}O{sub 2}/Fe(II) sobre components de Acidos Nucleicos. Estudio Cinetico

Abstract

The kinetic study of the action of a redox system on DNA monomers allowed us to make criticisms on radiomimetic character of this system. Assuming that in both cases, gamma radiolysis of aerated aqueous solutions and action of H{sub 2}O{sub 2} / Fe(II) system in the same conditions, the reactive species is the OH radical, we propose the kinetic expressions that are confirmed by our experimental results. Some of the accepted G-values are corrected in view of our results. Al so these results put in evidence mechanisms of molecular repair after radical attack. (Author) 79 refs.
Publication Date:
Jul 01, 1974
Product Type:
Technical Report
Report Number:
JEN-284
Subject:
73 NUCLEAR PHYSICS AND RADIATION PHYSICS; KINETICS; MECHANICS; GAMMA DECAY; REDOX PROCESS
OSTI ID:
21040073
Research Organizations:
Junta de Energia Nuclear (JEN), Madrid (Spain)
Country of Origin:
Spain
Language:
Spanish
Other Identifying Numbers:
TRN: ES08B0317
Availability:
Commercial reproduction prohibited; OSTI as DE21040073
Submitting Site:
SPN
Size:
117 pages
Announcement Date:
Aug 19, 2008

Citation Formats

Cirauqui, R, Mingot, F, and Davila, C A. Radiomimeticity of the system H{sub 2}O{sub 2}/Fe(II) on nucleic acid components. Kinetics study; Radiomimeticidad del sistema H{sub 2}O{sub 2}/Fe(II) sobre components de Acidos Nucleicos. Estudio Cinetico. Spain: N. p., 1974. Web.
Cirauqui, R, Mingot, F, & Davila, C A. Radiomimeticity of the system H{sub 2}O{sub 2}/Fe(II) on nucleic acid components. Kinetics study; Radiomimeticidad del sistema H{sub 2}O{sub 2}/Fe(II) sobre components de Acidos Nucleicos. Estudio Cinetico. Spain.
Cirauqui, R, Mingot, F, and Davila, C A. 1974. "Radiomimeticity of the system H{sub 2}O{sub 2}/Fe(II) on nucleic acid components. Kinetics study; Radiomimeticidad del sistema H{sub 2}O{sub 2}/Fe(II) sobre components de Acidos Nucleicos. Estudio Cinetico." Spain.
@misc{etde_21040073,
title = {Radiomimeticity of the system H{sub 2}O{sub 2}/Fe(II) on nucleic acid components. Kinetics study; Radiomimeticidad del sistema H{sub 2}O{sub 2}/Fe(II) sobre components de Acidos Nucleicos. Estudio Cinetico}
author = {Cirauqui, R, Mingot, F, and Davila, C A}
abstractNote = {The kinetic study of the action of a redox system on DNA monomers allowed us to make criticisms on radiomimetic character of this system. Assuming that in both cases, gamma radiolysis of aerated aqueous solutions and action of H{sub 2}O{sub 2} / Fe(II) system in the same conditions, the reactive species is the OH radical, we propose the kinetic expressions that are confirmed by our experimental results. Some of the accepted G-values are corrected in view of our results. Al so these results put in evidence mechanisms of molecular repair after radical attack. (Author) 79 refs.}
place = {Spain}
year = {1974}
month = {Jul}
}