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Diagnostic performance of the upper gastrointestinal series in the evaluation of children with clinically suspected malrotation

Abstract

Malrotation is a congenital disorder of abnormal intestinal rotation and fixation that predisposes infants to potentially life-threatening midgut volvulus. Upper gastrointestinal tract (UGI) examination is sometimes equivocal and can lead to inaccurate diagnosis. To determine the diagnostic performance of UGI examinations in children who subsequently underwent a Ladd procedure for suspected malrotation or volvulus. We reviewed all children up to 21 years old who had undergone both a UGI examination and a Ladd procedure for possible malrotation across 9 years. Children were excluded if they had not undergone either a UGI examination or a Ladd procedure and if congenital abdominal wall defects were present. Of 229 patients identified, 166 (59% male, median age 67 days) were included. Excluded were 47 without a UGI series, 12 with omphalocele or gastroschisis, 1 without verifiable operative data, 1 who had not undergone a Ladd procedure, and 2 older than 21 years. Of the 166 patients, 40% were neonates and 73% were <12 months old, and 31% presented with bilious vomiting and 15% with abdominal distention. Of 163 patients with surgically verified malrotation, 156 had a positive UGI examination, a sensitivity of 96%. There were two patients with a false-positive UGI examination and seven  More>>
Authors:
Sizemore, Alecia W; [1]  University of Virginia School of Medicine, Department of Radiology, Charlottesville, VA (United States)]; Rabbani, Kaneez Z; [2]  Ladd, Alan; [3]  Applegate, Kimberly E; [4]  Riley Hospital for Children, Department of Radiology, Indianapolis, IN (United States)]
  1. Indiana University School of Medicine, Department of Radiology, Indianapolis, IN (United States)
  2. Indiana University School of Medicine, Department of Medicine, Indianapolis, IN (United States)
  3. Indiana University School of Medicine, Division of Pediatric Surgery, Riley Hospital, Indianapolis, IN (United States)
  4. Indiana University School of Medicine, Section of Pediatric Radiology, Department of Radiology, Indianapolis, IN (United States)
Publication Date:
May 15, 2008
Product Type:
Journal Article
Resource Relation:
Journal Name: Pediatric Radiology; Journal Volume: 38; Journal Issue: 5
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BIOMEDICAL RADIOGRAPHY; CHILDREN; CONGENITAL DISEASES; DIGESTIVE SYSTEM DISEASES; GENETIC EFFECTS; GENETICS; LARGE INTESTINE
OSTI ID:
21030099
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0301-0449; PDRYA5; TRN: DE08F5024
Availability:
Available from: http://dx.doi.org/10.1007/s00247-008-0762-8
Submitting Site:
DEN
Size:
page(s) 518-528
Announcement Date:
Jun 02, 2008

Citation Formats

Sizemore, Alecia W, University of Virginia School of Medicine, Department of Radiology, Charlottesville, VA (United States)], Rabbani, Kaneez Z, Ladd, Alan, Applegate, Kimberly E, and Riley Hospital for Children, Department of Radiology, Indianapolis, IN (United States)]. Diagnostic performance of the upper gastrointestinal series in the evaluation of children with clinically suspected malrotation. Germany: N. p., 2008. Web. doi:10.1007/S00247-008-0762-8.
Sizemore, Alecia W, University of Virginia School of Medicine, Department of Radiology, Charlottesville, VA (United States)], Rabbani, Kaneez Z, Ladd, Alan, Applegate, Kimberly E, &amp; Riley Hospital for Children, Department of Radiology, Indianapolis, IN (United States)]. Diagnostic performance of the upper gastrointestinal series in the evaluation of children with clinically suspected malrotation. Germany. https://doi.org/10.1007/S00247-008-0762-8
Sizemore, Alecia W, University of Virginia School of Medicine, Department of Radiology, Charlottesville, VA (United States)], Rabbani, Kaneez Z, Ladd, Alan, Applegate, Kimberly E, and Riley Hospital for Children, Department of Radiology, Indianapolis, IN (United States)]. 2008. "Diagnostic performance of the upper gastrointestinal series in the evaluation of children with clinically suspected malrotation." Germany. https://doi.org/10.1007/S00247-008-0762-8.
@misc{etde_21030099,
title = {Diagnostic performance of the upper gastrointestinal series in the evaluation of children with clinically suspected malrotation}
author = {Sizemore, Alecia W, University of Virginia School of Medicine, Department of Radiology, Charlottesville, VA (United States)], Rabbani, Kaneez Z, Ladd, Alan, Applegate, Kimberly E, and Riley Hospital for Children, Department of Radiology, Indianapolis, IN (United States)]}
abstractNote = {Malrotation is a congenital disorder of abnormal intestinal rotation and fixation that predisposes infants to potentially life-threatening midgut volvulus. Upper gastrointestinal tract (UGI) examination is sometimes equivocal and can lead to inaccurate diagnosis. To determine the diagnostic performance of UGI examinations in children who subsequently underwent a Ladd procedure for suspected malrotation or volvulus. We reviewed all children up to 21 years old who had undergone both a UGI examination and a Ladd procedure for possible malrotation across 9 years. Children were excluded if they had not undergone either a UGI examination or a Ladd procedure and if congenital abdominal wall defects were present. Of 229 patients identified, 166 (59% male, median age 67 days) were included. Excluded were 47 without a UGI series, 12 with omphalocele or gastroschisis, 1 without verifiable operative data, 1 who had not undergone a Ladd procedure, and 2 older than 21 years. Of the 166 patients, 40% were neonates and 73% were <12 months old, and 31% presented with bilious vomiting and 15% with abdominal distention. Of 163 patients with surgically verified malrotation, 156 had a positive UGI examination, a sensitivity of 96%. There were two patients with a false-positive UGI examination and seven with false-negative examination. Jejunal position was normal in six of the seven with a false-negative examination and abnormal in the two with a false-positive examination. Of 38 patients with surgically verified volvulus, 30 showed volvulus on the UGI series. Five required bowel resection and three died. Jejunal position can lead to inaccurate UGI series interpretation. Meticulous technique and periodic assessment of performance will help more accurately diagnose difficult or equivocal cases. (orig.)}
doi = {10.1007/S00247-008-0762-8}
journal = []
issue = {5}
volume = {38}
place = {Germany}
year = {2008}
month = {May}
}