Abstract
Differential free radical activity of the fractionated extracts (F1: methanolic fraction, F2: acetone soluble fraction and F3: acetone insoluble fraction) of a medicinal plant Caesalpinia digyna, has been studied employing DPPH, superoxide radical and in vitro radioprotecting activity by following their effect on radiation induced protein carbonylation and DNA damage in pBR322. The activity for these fractions is in the order of F1>F2>F3. HPLC analysis indicated that all fractions contain high amount of bergenin, a polyhydroxy isocoumarin derivative and the fractions are more active than isolated bergenin. (author)
Singh, Umang;
Kunwar, A;
Barik, A;
Priyadarsini, K I;
[1]
Mula, S;
[2]
Srinivasan, R
[3]
- Radiation and Photochemistry Div., Bhabha Atomic Research Centre, Mumbai (India)
- Bio-Organic Div., Bhabha Atomic Research Centre, Mumbai (India)
- JSS College of Pharmacy, Ootacamund (India)
Citation Formats
Singh, Umang, Kunwar, A, Barik, A, Priyadarsini, K I, Mula, S, and Srinivasan, R.
Differential radioprotection and free radical scavenging activity of Caesalpinia digyna extracts and the active constituent.
India: N. p.,
2008.
Web.
Singh, Umang, Kunwar, A, Barik, A, Priyadarsini, K I, Mula, S, & Srinivasan, R.
Differential radioprotection and free radical scavenging activity of Caesalpinia digyna extracts and the active constituent.
India.
Singh, Umang, Kunwar, A, Barik, A, Priyadarsini, K I, Mula, S, and Srinivasan, R.
2008.
"Differential radioprotection and free radical scavenging activity of Caesalpinia digyna extracts and the active constituent."
India.
@misc{etde_21015053,
title = {Differential radioprotection and free radical scavenging activity of Caesalpinia digyna extracts and the active constituent}
author = {Singh, Umang, Kunwar, A, Barik, A, Priyadarsini, K I, Mula, S, and Srinivasan, R}
abstractNote = {Differential free radical activity of the fractionated extracts (F1: methanolic fraction, F2: acetone soluble fraction and F3: acetone insoluble fraction) of a medicinal plant Caesalpinia digyna, has been studied employing DPPH, superoxide radical and in vitro radioprotecting activity by following their effect on radiation induced protein carbonylation and DNA damage in pBR322. The activity for these fractions is in the order of F1>F2>F3. HPLC analysis indicated that all fractions contain high amount of bergenin, a polyhydroxy isocoumarin derivative and the fractions are more active than isolated bergenin. (author)}
place = {India}
year = {2008}
month = {Jan}
}
title = {Differential radioprotection and free radical scavenging activity of Caesalpinia digyna extracts and the active constituent}
author = {Singh, Umang, Kunwar, A, Barik, A, Priyadarsini, K I, Mula, S, and Srinivasan, R}
abstractNote = {Differential free radical activity of the fractionated extracts (F1: methanolic fraction, F2: acetone soluble fraction and F3: acetone insoluble fraction) of a medicinal plant Caesalpinia digyna, has been studied employing DPPH, superoxide radical and in vitro radioprotecting activity by following their effect on radiation induced protein carbonylation and DNA damage in pBR322. The activity for these fractions is in the order of F1>F2>F3. HPLC analysis indicated that all fractions contain high amount of bergenin, a polyhydroxy isocoumarin derivative and the fractions are more active than isolated bergenin. (author)}
place = {India}
year = {2008}
month = {Jan}
}