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Recent research on the pharmaceutical checking of radioelements (1961); Etudes recentes sur le controle pharmaceutique des radioelements (1961)

Abstract

Checking on radioactive preparations for medical use is complicated by difficulties due to the radioactivity, the instability and the methods of using these solutions. In effect it is necessary, in order to draw up a practicable set of rules governing such checks, to know both the method of preparation and the properties of the radioelement, as well as special and often contradictory features of its use. These tests fall into three categories: physical, chemical and biological. Preparations of chromium 51, iron 59 and arsenic 76 have been dealt with in recent studies. In each case special tests were necessary, and these will be described in this paper. The practice of these tests is of twofold interest: firstly they provide a maximum guarantee to the user, and secondly they guide the chemist in his manipulations, immediately and thoroughly. (author) [French] Le controle des preparations radioactives a usage medical est complexe par suite des difficultees dues a la radioactivite, a l'instabilite et aux modalites d'utilisation de ces solutions. En effet, l'etablissement justifie d'un protocole de controle necessite la connaissance aussi bien du mode de preparation, que des proprietes du radioelement et des particularites parfois contradictoires de son emploi. Ces controles sont de  More>>
Authors:
Cohen, Y; Ingrand, J [1] 
  1. Commissariat a l'Energie Atomique, Saclay (France).Centre d'Etudes Nucleaires
Publication Date:
Jul 01, 1960
Product Type:
Technical Report
Report Number:
CEA-R-1803
Resource Relation:
Other Information: 2 refs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; AQUEOUS SOLUTIONS; ARSENIC 76; BIOASSAY; CHEMICAL PREPARATION; CHROMIUM 51; GAMMA SPECTROSCOPY; IMPURITIES; IN VITRO; IN VIVO; IRON 59; ISOTOPE RATIO; QUALITY CONTROL; RADIONUCLIDE KINETICS; RADIOPHARMACEUTICALS; SZILARD-CHALMERS REACTION; TISSUE DISTRIBUTION; TOXICITY
OSTI ID:
20967987
Research Organizations:
CEA Saclay, 91 - Gif-sur-Yvette (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR07R1803116772
Availability:
Available from INIS in electronic form
Submitting Site:
FRN
Size:
16 pages
Announcement Date:
Dec 29, 2007

Citation Formats

Cohen, Y, and Ingrand, J. Recent research on the pharmaceutical checking of radioelements (1961); Etudes recentes sur le controle pharmaceutique des radioelements (1961). France: N. p., 1960. Web.
Cohen, Y, & Ingrand, J. Recent research on the pharmaceutical checking of radioelements (1961); Etudes recentes sur le controle pharmaceutique des radioelements (1961). France.
Cohen, Y, and Ingrand, J. 1960. "Recent research on the pharmaceutical checking of radioelements (1961); Etudes recentes sur le controle pharmaceutique des radioelements (1961)." France.
@misc{etde_20967987,
title = {Recent research on the pharmaceutical checking of radioelements (1961); Etudes recentes sur le controle pharmaceutique des radioelements (1961)}
author = {Cohen, Y, and Ingrand, J}
abstractNote = {Checking on radioactive preparations for medical use is complicated by difficulties due to the radioactivity, the instability and the methods of using these solutions. In effect it is necessary, in order to draw up a practicable set of rules governing such checks, to know both the method of preparation and the properties of the radioelement, as well as special and often contradictory features of its use. These tests fall into three categories: physical, chemical and biological. Preparations of chromium 51, iron 59 and arsenic 76 have been dealt with in recent studies. In each case special tests were necessary, and these will be described in this paper. The practice of these tests is of twofold interest: firstly they provide a maximum guarantee to the user, and secondly they guide the chemist in his manipulations, immediately and thoroughly. (author) [French] Le controle des preparations radioactives a usage medical est complexe par suite des difficultees dues a la radioactivite, a l'instabilite et aux modalites d'utilisation de ces solutions. En effet, l'etablissement justifie d'un protocole de controle necessite la connaissance aussi bien du mode de preparation, que des proprietes du radioelement et des particularites parfois contradictoires de son emploi. Ces controles sont de trois ordres physiques, chimiques, biologiques. Des etudes recentes ont porte sur des preparations de chrome 51, de fer 59, d'arsenic 76. Dans chaque cas, il est apparu necessaire de pratiquer des controles particuliers qui seront exposes dans la communication. La pratique de ces derniers presente un double interet; d'une part, ils assurent a l'utilisateur un maximum de garantie, d'autre part, ils orientent le chimiste dans ses mises au point, immediatement et de facon approfondie. (auteur)}
place = {France}
year = {1960}
month = {Jul}
}