Abstract
After nanoHA was synthesized, {sup 153}Sm-EDTMP-nanoHA and {sup 153}Sm-citrate-nanoHA were prepared and proved stable in vitro. ECT images of New Zealand rabbits injected with {sup 153}Sm-EDTMP-nanoHA had better contrast, skeletal figure visible, liver and spleen clear. The images of {sup 153}Sm-citrate-nanoHA showed a similar results but kidney invisible, which meant {sup 153}Sm-citrate-nanoHA showed a similar results but kidney invisible, which meant {sup 153}Sm-citrate-nanoHA was mainly excreted through liver and gall. {sup 153}Sm-EDTMP-nanoHA's half effective inhibition concentrations to SMMC-7721 and MCF-7 cells were 1.98 g/L and 0.075 g/L respectively and {sup 153}Sm-citrate-nanoHA's were 1.89 g/L and 0.094 g/L proportionally. {sup 153}Sm-EDTMP-nanoHA and {sup 153}Sm-citrate-nanoHA were worthy of a further research because their half effective inhibition concentrations were much lower than ones of the single nanoHA. (authors)
Wenzeng, Bing;
Shunzhong, Luo;
Guanghua, Wen;
Shubin, Jiang;
Xiaoling, Xiong;
Guoping, Liu
[1]
- China Academy of Engineering Physics, Mianyang (China). Inst. of Nuclear Physics and Chemistry
Citation Formats
Wenzeng, Bing, Shunzhong, Luo, Guanghua, Wen, Shubin, Jiang, Xiaoling, Xiong, and Guoping, Liu.
Synthesis and bio-evaluation of nano-hydroxyapatite trapped by {sup 153}Sm.
China: N. p.,
2006.
Web.
Wenzeng, Bing, Shunzhong, Luo, Guanghua, Wen, Shubin, Jiang, Xiaoling, Xiong, & Guoping, Liu.
Synthesis and bio-evaluation of nano-hydroxyapatite trapped by {sup 153}Sm.
China.
Wenzeng, Bing, Shunzhong, Luo, Guanghua, Wen, Shubin, Jiang, Xiaoling, Xiong, and Guoping, Liu.
2006.
"Synthesis and bio-evaluation of nano-hydroxyapatite trapped by {sup 153}Sm."
China.
@misc{etde_20960482,
title = {Synthesis and bio-evaluation of nano-hydroxyapatite trapped by {sup 153}Sm}
author = {Wenzeng, Bing, Shunzhong, Luo, Guanghua, Wen, Shubin, Jiang, Xiaoling, Xiong, and Guoping, Liu}
abstractNote = {After nanoHA was synthesized, {sup 153}Sm-EDTMP-nanoHA and {sup 153}Sm-citrate-nanoHA were prepared and proved stable in vitro. ECT images of New Zealand rabbits injected with {sup 153}Sm-EDTMP-nanoHA had better contrast, skeletal figure visible, liver and spleen clear. The images of {sup 153}Sm-citrate-nanoHA showed a similar results but kidney invisible, which meant {sup 153}Sm-citrate-nanoHA showed a similar results but kidney invisible, which meant {sup 153}Sm-citrate-nanoHA was mainly excreted through liver and gall. {sup 153}Sm-EDTMP-nanoHA's half effective inhibition concentrations to SMMC-7721 and MCF-7 cells were 1.98 g/L and 0.075 g/L respectively and {sup 153}Sm-citrate-nanoHA's were 1.89 g/L and 0.094 g/L proportionally. {sup 153}Sm-EDTMP-nanoHA and {sup 153}Sm-citrate-nanoHA were worthy of a further research because their half effective inhibition concentrations were much lower than ones of the single nanoHA. (authors)}
place = {China}
year = {2006}
month = {Mar}
}
title = {Synthesis and bio-evaluation of nano-hydroxyapatite trapped by {sup 153}Sm}
author = {Wenzeng, Bing, Shunzhong, Luo, Guanghua, Wen, Shubin, Jiang, Xiaoling, Xiong, and Guoping, Liu}
abstractNote = {After nanoHA was synthesized, {sup 153}Sm-EDTMP-nanoHA and {sup 153}Sm-citrate-nanoHA were prepared and proved stable in vitro. ECT images of New Zealand rabbits injected with {sup 153}Sm-EDTMP-nanoHA had better contrast, skeletal figure visible, liver and spleen clear. The images of {sup 153}Sm-citrate-nanoHA showed a similar results but kidney invisible, which meant {sup 153}Sm-citrate-nanoHA showed a similar results but kidney invisible, which meant {sup 153}Sm-citrate-nanoHA was mainly excreted through liver and gall. {sup 153}Sm-EDTMP-nanoHA's half effective inhibition concentrations to SMMC-7721 and MCF-7 cells were 1.98 g/L and 0.075 g/L respectively and {sup 153}Sm-citrate-nanoHA's were 1.89 g/L and 0.094 g/L proportionally. {sup 153}Sm-EDTMP-nanoHA and {sup 153}Sm-citrate-nanoHA were worthy of a further research because their half effective inhibition concentrations were much lower than ones of the single nanoHA. (authors)}
place = {China}
year = {2006}
month = {Mar}
}