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Design and use of numerical anatomical atlases for radiotherapy; Creation et utilisation d'atlas anatomiques numeriques pour la radiotherapie

Abstract

The main objective of this thesis is to provide radio-oncology specialists with automatic tools for delineating organs at risk of a patient undergoing a radiotherapy treatment of cerebral or head and neck tumors. To achieve this goal, we use an anatomical atlas, i.e. a representative anatomy associated to a clinical image representing it. The registration of this atlas allows us to segment automatically the patient structures and to accelerate this process. Contributions in this method are presented on three axes. First, we want to obtain a registration method which is as independent as possible from the setting of its parameters. This setting, done by the clinician, indeed needs to be minimal while guaranteeing a robust result. We therefore propose registration methods allowing a better control of the obtained transformation, using rejection techniques of inadequate matching or locally affine transformations. The second axis is dedicated to the consideration of structures associated with the presence of the tumor. These structures, not present in the atlas, indeed lead to local errors in the atlas-based segmentation. We therefore propose methods to delineate these structures and take them into account in the registration. Finally, we present the construction of an anatomical atlas of the head  More>>
Authors:
Publication Date:
Feb 15, 2007
Product Type:
Thesis/Dissertation
Report Number:
FRNC-TH-7055
Resource Relation:
Other Information: TH: These sciences, informatique; 173 refs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; IMAGE PROCESSING; NEOPLASMS; NERVES; POSITIONING; RADIOTHERAPY
OSTI ID:
20953819
Research Organizations:
Nice Univ. Sophia Antipolis, 06 (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR0702027105131
Availability:
Available from INIS in electronic form
Submitting Site:
FRN
Size:
200 pages
Announcement Date:
Dec 27, 2007

Citation Formats

Commowick, O. Design and use of numerical anatomical atlases for radiotherapy; Creation et utilisation d'atlas anatomiques numeriques pour la radiotherapie. France: N. p., 2007. Web.
Commowick, O. Design and use of numerical anatomical atlases for radiotherapy; Creation et utilisation d'atlas anatomiques numeriques pour la radiotherapie. France.
Commowick, O. 2007. "Design and use of numerical anatomical atlases for radiotherapy; Creation et utilisation d'atlas anatomiques numeriques pour la radiotherapie." France.
@misc{etde_20953819,
title = {Design and use of numerical anatomical atlases for radiotherapy; Creation et utilisation d'atlas anatomiques numeriques pour la radiotherapie}
author = {Commowick, O}
abstractNote = {The main objective of this thesis is to provide radio-oncology specialists with automatic tools for delineating organs at risk of a patient undergoing a radiotherapy treatment of cerebral or head and neck tumors. To achieve this goal, we use an anatomical atlas, i.e. a representative anatomy associated to a clinical image representing it. The registration of this atlas allows us to segment automatically the patient structures and to accelerate this process. Contributions in this method are presented on three axes. First, we want to obtain a registration method which is as independent as possible from the setting of its parameters. This setting, done by the clinician, indeed needs to be minimal while guaranteeing a robust result. We therefore propose registration methods allowing a better control of the obtained transformation, using rejection techniques of inadequate matching or locally affine transformations. The second axis is dedicated to the consideration of structures associated with the presence of the tumor. These structures, not present in the atlas, indeed lead to local errors in the atlas-based segmentation. We therefore propose methods to delineate these structures and take them into account in the registration. Finally, we present the construction of an anatomical atlas of the head and neck region and its evaluation on a database of patients. We show in this part the feasibility of the use of an atlas for this region, as well as a simple method to evaluate the registration methods used to build an atlas. All this research work has been implemented in a commercial software (Imago from DOSIsoft), allowing us to validate our results in clinical conditions. (author)}
place = {France}
year = {2007}
month = {Feb}
}