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Prognostic value of bone involvement in patients with squamous cell carcinoma of the external and middle ear

Abstract

The incidence of the external and middle ear squamous cell carcinoma (SCC) is extremely rare in the head and neck cancer with less than 1%. Therefore, the correlation between the staging classification and the prognosis has not been clear. Prognostic factors for patients with the external and middle ear SCC were assessed in the initial clinical symptoms and radiographic imaging. 13 patients with the external and middle ear SCC (5 male and 8 female) that had been treated at the Department of Otorhinolaryngology, Kanazawa University hospital from 2000 to 2006 were selected for this study. The radiation therapy followed surgery in ten patients. One patient received the radical cure irradiation before surgery. Two patients received a surgical excision alone. The temporal bone involvement and the parotid gland involvement in the radiographic image (computed tomography imaging and/or magnetic resonance imaging) were assessed. Clinical symptoms (otalgia, hearing disturbance, tinnitus, vertigo and facial nerve palsy) before treatment were reviewed based on the medical record. The correlation of those clinical factors and T staging in the Pittsburgh classification with overall survival was statistically assessed. The temporal bone involvement significantly correlated with worse prognosis. However, parotid gland involvement did not influence the prognosis. Moreover, statistically  More>>
Authors:
Shiga, Hideaki; Ito, Makoto; Uramoto, Naoki; Hatano, Miyako; Miwa, Takaki; Furukawa, Mitsuru [1] 
  1. Kanazawa Univ., Graduate School of Medical Science, Kanazawa, Ishikawa (Japan)
Publication Date:
May 15, 2007
Product Type:
Journal Article
Resource Relation:
Journal Name: Otology Japan; Journal Volume: 17; Journal Issue: 2
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; AUDITORY ORGANS; CARCINOMAS; CAT SCANNING; HEARINGS; NMR IMAGING; PATIENTS; RADIOTHERAPY; SURGERY; SURVIVAL CURVES
OSTI ID:
20950404
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: ISSN 0917-2025; OTJAEW; TRN: JP0703419100628
Submitting Site:
INIS
Size:
page(s) 128-132
Announcement Date:
Dec 27, 2007

Citation Formats

Shiga, Hideaki, Ito, Makoto, Uramoto, Naoki, Hatano, Miyako, Miwa, Takaki, and Furukawa, Mitsuru. Prognostic value of bone involvement in patients with squamous cell carcinoma of the external and middle ear. Japan: N. p., 2007. Web.
Shiga, Hideaki, Ito, Makoto, Uramoto, Naoki, Hatano, Miyako, Miwa, Takaki, & Furukawa, Mitsuru. Prognostic value of bone involvement in patients with squamous cell carcinoma of the external and middle ear. Japan.
Shiga, Hideaki, Ito, Makoto, Uramoto, Naoki, Hatano, Miyako, Miwa, Takaki, and Furukawa, Mitsuru. 2007. "Prognostic value of bone involvement in patients with squamous cell carcinoma of the external and middle ear." Japan.
@misc{etde_20950404,
title = {Prognostic value of bone involvement in patients with squamous cell carcinoma of the external and middle ear}
author = {Shiga, Hideaki, Ito, Makoto, Uramoto, Naoki, Hatano, Miyako, Miwa, Takaki, and Furukawa, Mitsuru}
abstractNote = {The incidence of the external and middle ear squamous cell carcinoma (SCC) is extremely rare in the head and neck cancer with less than 1%. Therefore, the correlation between the staging classification and the prognosis has not been clear. Prognostic factors for patients with the external and middle ear SCC were assessed in the initial clinical symptoms and radiographic imaging. 13 patients with the external and middle ear SCC (5 male and 8 female) that had been treated at the Department of Otorhinolaryngology, Kanazawa University hospital from 2000 to 2006 were selected for this study. The radiation therapy followed surgery in ten patients. One patient received the radical cure irradiation before surgery. Two patients received a surgical excision alone. The temporal bone involvement and the parotid gland involvement in the radiographic image (computed tomography imaging and/or magnetic resonance imaging) were assessed. Clinical symptoms (otalgia, hearing disturbance, tinnitus, vertigo and facial nerve palsy) before treatment were reviewed based on the medical record. The correlation of those clinical factors and T staging in the Pittsburgh classification with overall survival was statistically assessed. The temporal bone involvement significantly correlated with worse prognosis. However, parotid gland involvement did not influence the prognosis. Moreover, statistically significant difference in T staging of the Pittsburgh classification (T1{center_dot}T2 vs. T3{center_dot}T4) was not found. The temporal bone involvement in the radiographic image was a prognostic factor for patients with the external and middle ear SCC. Pittsburgh classification needs to be modified because the bony part of the external auditory canal involvement is considered as T2 stage and the soft tissue involvement is defined as T4 stage. (author)}
journal = []
issue = {2}
volume = {17}
place = {Japan}
year = {2007}
month = {May}
}