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Clinical usefulness of MRI and MRA in children with partial epilepsy; Ocena znaczenia klinicznego obrazowania MRI i MRA w padaczce czesciowej u dzieci

Abstract

Partial epilepsy is a very important problem of epileptology in childhood including clinical and therapeutic aspect especially surgery treatment. The aim of this study is to assess clinical value of neuroimagine techniques (structural MRI, MRI angiography) in partial epilepsy diagnostics in children. The relation between results of examinations with these methods and congenital and acquired risk factors related to partial epilepsy, age of its onset and clinical assessment of patients was analyzed. The study group consisted of 140 children with partial epilepsy hospitalized between 1998 and 2004 in Department of Pediatric Neurology, Collegium Medicum Jagiellonian University, Krakow. The group included 70 girls and 70 boys, the age ranged from 2 months to 17 years. In study group statistical analysis included different factors as which can be related with results of neuroimaging as age, load of pregnancy and birth period, familiar epilepsy, patient's risk factors for appearance of epilepsy, acquired risk factors of epilepsy, results of neurological examination, type of epilepsy, status epilepticus, and signs according epileptic attacks which can be related with neuroimaging results. The primary method of neuroimagine in all patients was structural MRI, in 16 cases Magnetic Resonance Angiography (MRA). The parametric tests (t-student), nonparametric Mann-Whitney's test were  More>>
Authors:
Zajac, A; Kacinski, M; Kubik, A; Kroczka, S [1] 
  1. Klinika Neurologii Dzieciecej, Uniwersytet Jagiellonski, Collegium Medicum, Cracow (Poland)
Publication Date:
Jul 01, 2006
Product Type:
Journal Article
Resource Relation:
Journal Name: Polish Journal of Radiology; Journal Volume: 71; Journal Issue: 3; Other Information: 50 refs., 9 figs., 4 tabs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARTERIES; BIOMEDICAL RADIOGRAPHY; BRAIN; CHILDREN; DIAGNOSTIC TECHNIQUES; EPILEPSY; HIPPOCAMPUS; IMAGE PROCESSING; MAGNETIC RESONANCE; NERVOUS SYSTEM DISEASES
OSTI ID:
20938379
Country of Origin:
Poland
Language:
Polish
Other Identifying Numbers:
Journal ID: ISSN 1733-134X; TRN: PL0700752082727
Submitting Site:
INIS
Size:
page(s) 64-73
Announcement Date:
Nov 13, 2007

Citation Formats

Zajac, A, Kacinski, M, Kubik, A, and Kroczka, S. Clinical usefulness of MRI and MRA in children with partial epilepsy; Ocena znaczenia klinicznego obrazowania MRI i MRA w padaczce czesciowej u dzieci. Poland: N. p., 2006. Web.
Zajac, A, Kacinski, M, Kubik, A, & Kroczka, S. Clinical usefulness of MRI and MRA in children with partial epilepsy; Ocena znaczenia klinicznego obrazowania MRI i MRA w padaczce czesciowej u dzieci. Poland.
Zajac, A, Kacinski, M, Kubik, A, and Kroczka, S. 2006. "Clinical usefulness of MRI and MRA in children with partial epilepsy; Ocena znaczenia klinicznego obrazowania MRI i MRA w padaczce czesciowej u dzieci." Poland.
@misc{etde_20938379,
title = {Clinical usefulness of MRI and MRA in children with partial epilepsy; Ocena znaczenia klinicznego obrazowania MRI i MRA w padaczce czesciowej u dzieci}
author = {Zajac, A, Kacinski, M, Kubik, A, and Kroczka, S}
abstractNote = {Partial epilepsy is a very important problem of epileptology in childhood including clinical and therapeutic aspect especially surgery treatment. The aim of this study is to assess clinical value of neuroimagine techniques (structural MRI, MRI angiography) in partial epilepsy diagnostics in children. The relation between results of examinations with these methods and congenital and acquired risk factors related to partial epilepsy, age of its onset and clinical assessment of patients was analyzed. The study group consisted of 140 children with partial epilepsy hospitalized between 1998 and 2004 in Department of Pediatric Neurology, Collegium Medicum Jagiellonian University, Krakow. The group included 70 girls and 70 boys, the age ranged from 2 months to 17 years. In study group statistical analysis included different factors as which can be related with results of neuroimaging as age, load of pregnancy and birth period, familiar epilepsy, patient's risk factors for appearance of epilepsy, acquired risk factors of epilepsy, results of neurological examination, type of epilepsy, status epilepticus, and signs according epileptic attacks which can be related with neuroimaging results. The primary method of neuroimagine in all patients was structural MRI, in 16 cases Magnetic Resonance Angiography (MRA). The parametric tests (t-student), nonparametric Mann-Whitney's test were used in statistical analysis. The bilateral Fisher test was used to check rate in groups. There was assessed sensitivity, specificity, positive predictive value, negative predictive value; the 95% confidence interval was calculated for these parameters. Abnormalities in neurological examination in children with partial epilepsy were strongly correlated with MRI findings. The structural changes in MRI were found in younger children, whose course of epilepsy was longer than children without MRI changes. Changes in hippocampus ere the most common in children with partial epilepsy with abnormalities in MRI. Children with migration disorder had big variety of clinical symptoms. Neuroimaging by MRI is particularly important in younger children, with longer course of epilepsy and abnormal neurological examination and for detecting of migration and hippocampal changes. (author)}
journal = []
issue = {3}
volume = {71}
place = {Poland}
year = {2006}
month = {Jul}
}