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Use of ion exchange and early treatment of radioactive contamination in the digestive tract; Utilisation des echangeurs d'ions et traitement precoce de la contamination radioactive par voie digestive

Abstract

The efficiency of cation exchange resins for the treatment of digestive contamination with strontium has been studied on rats. The results obtained show that the most efficient resins are those of sulfonic type when administered in the ammonium form. The treatment is still efficient when applied 45 minutes after the ingestion of strontium. In the most favourable cases, the radioactivity of the skeleton was lower by a factor 6 in the treated animals than in controls. This easily applicable, rather safe and non specific treatment deserves to be retained for use. (author) [French] Une etude de l'efficacite des resines echangeuses de cations dans le traitement d'une contamination digestive par le strontium a ete entreprise chez le rat. Les resultats montrent que parmi les resines, les plus efficaces sont celles de type sulfonique, administrees sous forme ammonium. Le traitement est encore efficace 45 minutes apres l'ingestion du strontium. Dans les meilleurs cas, le squelette des rats traites etait six fois moins radioactif que celui des temoins. Ce traitement d'emploi facile, peu dangereux, non specifique, merite d'etre retenu. (auteur)
Authors:
Michon, G; Guilloux, M J [1] 
  1. Commissariat a l'Energie Atomique, Saclay (France). Centre d'Etudes Nucleaires
Publication Date:
Jul 01, 1958
Product Type:
Technical Report
Report Number:
CEA-R-1047
Resource Relation:
Other Information: 6 refs
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; CATIONS; CLEARANCE; COMPARATIVE EVALUATIONS; CONTAMINATION; EFFICIENCY; INGESTION; ION EXCHANGE; LABORATORY ANIMALS; ORAL ADMINISTRATION; ORGANIC ION EXCHANGERS; RADIONUCLIDE KINETICS; RATS; RESINS; SKELETON; STRONTIUM 90; THERAPY
OSTI ID:
20912763
Research Organizations:
CEA Saclay, 91 - Gif-sur-Yvette (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR07R1047073939
Availability:
Available from INIS in electronic form
Submitting Site:
FRN
Size:
11 pages
Announcement Date:
Sep 24, 2007

Citation Formats

Michon, G, and Guilloux, M J. Use of ion exchange and early treatment of radioactive contamination in the digestive tract; Utilisation des echangeurs d'ions et traitement precoce de la contamination radioactive par voie digestive. France: N. p., 1958. Web.
Michon, G, & Guilloux, M J. Use of ion exchange and early treatment of radioactive contamination in the digestive tract; Utilisation des echangeurs d'ions et traitement precoce de la contamination radioactive par voie digestive. France.
Michon, G, and Guilloux, M J. 1958. "Use of ion exchange and early treatment of radioactive contamination in the digestive tract; Utilisation des echangeurs d'ions et traitement precoce de la contamination radioactive par voie digestive." France.
@misc{etde_20912763,
title = {Use of ion exchange and early treatment of radioactive contamination in the digestive tract; Utilisation des echangeurs d'ions et traitement precoce de la contamination radioactive par voie digestive}
author = {Michon, G, and Guilloux, M J}
abstractNote = {The efficiency of cation exchange resins for the treatment of digestive contamination with strontium has been studied on rats. The results obtained show that the most efficient resins are those of sulfonic type when administered in the ammonium form. The treatment is still efficient when applied 45 minutes after the ingestion of strontium. In the most favourable cases, the radioactivity of the skeleton was lower by a factor 6 in the treated animals than in controls. This easily applicable, rather safe and non specific treatment deserves to be retained for use. (author) [French] Une etude de l'efficacite des resines echangeuses de cations dans le traitement d'une contamination digestive par le strontium a ete entreprise chez le rat. Les resultats montrent que parmi les resines, les plus efficaces sont celles de type sulfonique, administrees sous forme ammonium. Le traitement est encore efficace 45 minutes apres l'ingestion du strontium. Dans les meilleurs cas, le squelette des rats traites etait six fois moins radioactif que celui des temoins. Ce traitement d'emploi facile, peu dangereux, non specifique, merite d'etre retenu. (auteur)}
place = {France}
year = {1958}
month = {Jul}
}