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Evaluation of the persistence in the induction of Sister Chromatid Exchanges (SCE) by alkylating agents; Evaluacion de la persistencia en la induccion de Intercambio en las Cromatidas Hermanas (ICH) por agentes alquilantes

Abstract

The persistence in the induction of sister chromatid exchanges (SCE) by the alkylating agents methyl and ethyl-methanesulfonates (MMS and EMS) was evaluated. For it, to groups of mice its were administered a dose of these agents and later its were analyzed the induced SCE's in two periods: early and late. Both agents caused high increments of SCE in the early period and small in the late one; however, the caused lately by EMS was significantly bigger. This late induction of SCE by EMS possibly is associated with an epigenetic change or with the presence of etiladucts in the phosphodiester bonds of the DNA. (Author)
Authors:
Rodriguez R, R; Huerta V, C; MOrales R, P R [1] 
  1. ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)
Publication Date:
Jul 01, 2006
Product Type:
Conference
Report Number:
INIS-MX-2254
Resource Relation:
Conference: 16. ININ-SUTIN Technical and Scientific Congress, Salazar, Estado de Mexico (Mexico), 6-7 Dec 2006
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; ALKYLATING AGENTS; BONE MARROW; DIAGRAMS; DNA; IN VIVO; METHYL METHANESULFONATE; MICE; OPTICAL MICROSCOPY; PHOSPHODIESTERASES; SISTER CHROMATID EXCHANGES; STATISTICS; TIME DEPENDENCE
OSTI ID:
20899212
Research Organizations:
Instituto Nacional de Investigaciones Nucleares. Sindicato Unico de Trabajadores de la Industria Nuclear (Mexico)
Country of Origin:
Mexico
Language:
Spanish
Other Identifying Numbers:
TRN: MX0700287061409
Availability:
Available from INIS in electronic form
Submitting Site:
MXN
Size:
6 pages
Announcement Date:
Aug 28, 2007

Citation Formats

Rodriguez R, R, Huerta V, C, and MOrales R, P R. Evaluation of the persistence in the induction of Sister Chromatid Exchanges (SCE) by alkylating agents; Evaluacion de la persistencia en la induccion de Intercambio en las Cromatidas Hermanas (ICH) por agentes alquilantes. Mexico: N. p., 2006. Web.
Rodriguez R, R, Huerta V, C, & MOrales R, P R. Evaluation of the persistence in the induction of Sister Chromatid Exchanges (SCE) by alkylating agents; Evaluacion de la persistencia en la induccion de Intercambio en las Cromatidas Hermanas (ICH) por agentes alquilantes. Mexico.
Rodriguez R, R, Huerta V, C, and MOrales R, P R. 2006. "Evaluation of the persistence in the induction of Sister Chromatid Exchanges (SCE) by alkylating agents; Evaluacion de la persistencia en la induccion de Intercambio en las Cromatidas Hermanas (ICH) por agentes alquilantes." Mexico.
@misc{etde_20899212,
title = {Evaluation of the persistence in the induction of Sister Chromatid Exchanges (SCE) by alkylating agents; Evaluacion de la persistencia en la induccion de Intercambio en las Cromatidas Hermanas (ICH) por agentes alquilantes}
author = {Rodriguez R, R, Huerta V, C, and MOrales R, P R}
abstractNote = {The persistence in the induction of sister chromatid exchanges (SCE) by the alkylating agents methyl and ethyl-methanesulfonates (MMS and EMS) was evaluated. For it, to groups of mice its were administered a dose of these agents and later its were analyzed the induced SCE's in two periods: early and late. Both agents caused high increments of SCE in the early period and small in the late one; however, the caused lately by EMS was significantly bigger. This late induction of SCE by EMS possibly is associated with an epigenetic change or with the presence of etiladucts in the phosphodiester bonds of the DNA. (Author)}
place = {Mexico}
year = {2006}
month = {Jul}
}