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Absorption and fluorescence studies of curcumin bound to liposomes and lymphocytes: effect of {gamma}- irradiation

Abstract

Absorption and fluorescence spectral changes in curcumin were employed to follow its binding to liposomes and lymphocytes. The association constants indicated high affinity of curcumin to liposomes. Tumor lymphocytes show mere intense fluorescence of curcumin over the normal lymphocytes. The loss of curcumin in cells after {gamma}-irradiation could be followed by reduction in curcumin fluorescence. The studies indicate that such fluorescence changes can be used as markers to understand the preferential loading of curcumin to cells. (author)
Authors:
Kunwar, Amit; Barik, A; Indira Priyadarsini, K; [1]  Pandey, R [2] 
  1. Radiation and Photochemistry Division, Bhabha Atomic Research Centre, Mumbai (India)
  2. Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Mumbai (India)
Publication Date:
Jan 15, 2006
Product Type:
Conference
Resource Relation:
Conference: TSRP-2006: 8. Trombay symposium on radiation and photochemistry, Mumbai (India), 5-9 Jan 2006; Other Information: 2 refs; Related Information: In: Proceedings of the eighth biennial Trombay symposium on radiation and photochemistry. V. 2 : posters, 321 pages.
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; ABSORPTION; BIOLOGICAL MARKERS; CURCUMIN; FLUORESCENCE; GAMMA RADIATION; LIPOSOMES; LYMPHOCYTES; RADIATION DOSES
OSTI ID:
20898019
Research Organizations:
Board of Research in Nuclear Sciences, Dept. of Atomic Energy, Mumbai (India); Indian Society for Radiation and Photochemical Sciences, Mumbai (India)
Country of Origin:
India
Language:
English
Other Identifying Numbers:
Other: ISBN 81-88513-19-9; TRN: IN0700798060193
Submitting Site:
INIS
Size:
page(s) 25-26
Announcement Date:
Aug 30, 2007

Citation Formats

Kunwar, Amit, Barik, A, Indira Priyadarsini, K, and Pandey, R. Absorption and fluorescence studies of curcumin bound to liposomes and lymphocytes: effect of {gamma}- irradiation. India: N. p., 2006. Web.
Kunwar, Amit, Barik, A, Indira Priyadarsini, K, & Pandey, R. Absorption and fluorescence studies of curcumin bound to liposomes and lymphocytes: effect of {gamma}- irradiation. India.
Kunwar, Amit, Barik, A, Indira Priyadarsini, K, and Pandey, R. 2006. "Absorption and fluorescence studies of curcumin bound to liposomes and lymphocytes: effect of {gamma}- irradiation." India.
@misc{etde_20898019,
title = {Absorption and fluorescence studies of curcumin bound to liposomes and lymphocytes: effect of {gamma}- irradiation}
author = {Kunwar, Amit, Barik, A, Indira Priyadarsini, K, and Pandey, R}
abstractNote = {Absorption and fluorescence spectral changes in curcumin were employed to follow its binding to liposomes and lymphocytes. The association constants indicated high affinity of curcumin to liposomes. Tumor lymphocytes show mere intense fluorescence of curcumin over the normal lymphocytes. The loss of curcumin in cells after {gamma}-irradiation could be followed by reduction in curcumin fluorescence. The studies indicate that such fluorescence changes can be used as markers to understand the preferential loading of curcumin to cells. (author)}
place = {India}
year = {2006}
month = {Jan}
}