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Relationship among the repair mechanisms and the genetic recombination; Relacion entre los mecanismos de reparacion y la recombinacion genetica

Abstract

In accordance with the previous reports of the Project BZ87 of the Department of Radiobiology, a dependent stimulation of the system exists in E.coli SOS, of the recombination of the bacteriophage Lambda whose genetic material has not been damaged. This stimulation is not due to the increase of the cellular concentration of the protein RecA and the mechanism but probable for which we find that it is carried out, it is through a cooperation among the product of the gene rec N of E. coli and the system Net of recombination of Lambda. The gene recN belongs to the group of genes SOS and its expression is induced when damaging the bacterial DNA where it intervenes in the repair of breaks of the double helix of the molecule (Picksley et, 1984). If the repair of breaks of this type is a factor that limits the speed with which it happens the recombination among viral chromosomes, then the biggest readiness in the protein RecN, due to the induction of the functions SOS, would facilitate the repair of such ruptures. In this new project it is to enlarge the knowledge about this phenomenon, it was, on one hand of corroborating in a  More>>
Authors:
Alcantara D, D [1] 
  1. ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)
Publication Date:
Dec 15, 1987
Product Type:
Technical Report
Report Number:
RADIOBIOL-87-08; INIS-MX-RI-0307
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; BACTERIA; BACTERIOPHAGES; BIOLOGICAL REPAIR; CULTURE MEDIA; DNA; ESCHERICHIA COLI; EXPERIMENTAL DATA; GENE RECOMBINATION; GENES; INFECTIVITY; MAGNESIUM SULFATES; MUTANTS; MUTATIONS; PEPTONE; PROTEINS; TIME DEPENDENCE; ULTRAVIOLET RADIATION; VIRUSES
OSTI ID:
20896041
Research Organizations:
Instituto Nacional de Investigaciones Nucleares, Ocoyoacac (Mexico)
Country of Origin:
Mexico
Language:
Spanish
Other Identifying Numbers:
TRN: MX0700132059610
Availability:
Available from INIS in electronic form
Submitting Site:
MXN
Size:
22 pages
Announcement Date:
Aug 13, 2007

Citation Formats

Alcantara D, D. Relationship among the repair mechanisms and the genetic recombination; Relacion entre los mecanismos de reparacion y la recombinacion genetica. Mexico: N. p., 1987. Web.
Alcantara D, D. Relationship among the repair mechanisms and the genetic recombination; Relacion entre los mecanismos de reparacion y la recombinacion genetica. Mexico.
Alcantara D, D. 1987. "Relationship among the repair mechanisms and the genetic recombination; Relacion entre los mecanismos de reparacion y la recombinacion genetica." Mexico.
@misc{etde_20896041,
title = {Relationship among the repair mechanisms and the genetic recombination; Relacion entre los mecanismos de reparacion y la recombinacion genetica}
author = {Alcantara D, D}
abstractNote = {In accordance with the previous reports of the Project BZ87 of the Department of Radiobiology, a dependent stimulation of the system exists in E.coli SOS, of the recombination of the bacteriophage Lambda whose genetic material has not been damaged. This stimulation is not due to the increase of the cellular concentration of the protein RecA and the mechanism but probable for which we find that it is carried out, it is through a cooperation among the product of the gene rec N of E. coli and the system Net of recombination of Lambda. The gene recN belongs to the group of genes SOS and its expression is induced when damaging the bacterial DNA where it intervenes in the repair of breaks of the double helix of the molecule (Picksley et, 1984). If the repair of breaks of this type is a factor that limits the speed with which it happens the recombination among viral chromosomes, then the biggest readiness in the protein RecN, due to the induction of the functions SOS, would facilitate the repair of such ruptures. In this new project it is to enlarge the knowledge about this phenomenon, it was, on one hand of corroborating in a way but he/she specifies the relationship between the recombinogenic response of Lambda and the System SOS of E. coli and for the other one to determine the effect that has the inhibition of the duplication of the DNA on the stimulation of the viral recombination. Everything it with the idea of making it but evident and to be able to use it as a system of genotoxic agents detection in E. coli. (Author)}
place = {Mexico}
year = {1987}
month = {Dec}
}