Abstract
Cystic fibrosis (CF) is the most frequent inherited disorder leading to premature death in the Caucasian population. As life expectancy is limited by pulmonary complications, repeated imaging [chest X-ray, multislice high-resolution computed tomography (MS-HRCT)] is required in the follow-up. Magnetic resonance imaging (MRI) of the lung parenchyma is a promising new diagnostic tool. Its value for imaging lung changes caused by CF compared with CT is demonstrated. MRI performs well when compared with CT, which serves as the gold standard. Its lack in spatial resolution is obvious, but advantages in contrast and functional assessment compensate for this limitation. Thus, MRI is a reasonable alternative for imaging the CF lung and should be introduced as a radiation-free modality for follow-up studies in CF patients. For further evaluation of the impact of MRI, systematic studies comparing MRI and conventional imaging modalities are necessary. Furthermore, the value of the additional functional MRI (fMRI) information has to be studied, and a scoring system for the morphological and functional aspect of MRI has to be established. (orig.)
Puderbach, Michael;
Eichinger, Monika;
Kauczor, Hans-Ulrich;
[1]
Gahr, Julie;
Mueller, Frank-Michael;
[2]
Ley, Sebastian;
[1]
Childrens Hospital, University Heidelberg, Department of Pediatric Radiology, Heidelberg (Germany)];
Tuengerthal, Siegfried;
Schmaehl, Astrid;
[3]
Fink, Christian;
[1]
University of Munich, Medical Center Grosshadern, Institute of Clinical Radiology, Munich (Germany)];
Plathow, Christian;
[1]
University of Tuebingen, Department of Radiology, Tuebingen (Germany)];
Wiebel, Matthias
[4]
- Department of Radiology (E010), DKFZ, Heidelberg (Germany)
- Childrens Hospital, University Heidelberg, Department of Pediatric Pulmonology, Cystic Fibrosis Center and Infectious Diseases, Heidelberg (Germany)
- Thoraxklinik am Universitaetsklinikum Heidelberg, Department of Radiology, Heidelberg (Germany)
- Thoraxklinik am Universitaetsklinikum Heidelberg, Department of Pulmonology, Heidelberg (Germany)
Citation Formats
Puderbach, Michael, Eichinger, Monika, Kauczor, Hans-Ulrich, Gahr, Julie, Mueller, Frank-Michael, Ley, Sebastian, Childrens Hospital, University Heidelberg, Department of Pediatric Radiology, Heidelberg (Germany)], Tuengerthal, Siegfried, Schmaehl, Astrid, Fink, Christian, University of Munich, Medical Center Grosshadern, Institute of Clinical Radiology, Munich (Germany)], Plathow, Christian, University of Tuebingen, Department of Radiology, Tuebingen (Germany)], and Wiebel, Matthias.
Proton MRI appearance of cystic fibrosis: Comparison to CT.
Germany: N. p.,
2007.
Web.
doi:10.1007/S00330-006-0373-4.
Puderbach, Michael, Eichinger, Monika, Kauczor, Hans-Ulrich, Gahr, Julie, Mueller, Frank-Michael, Ley, Sebastian, Childrens Hospital, University Heidelberg, Department of Pediatric Radiology, Heidelberg (Germany)], Tuengerthal, Siegfried, Schmaehl, Astrid, Fink, Christian, University of Munich, Medical Center Grosshadern, Institute of Clinical Radiology, Munich (Germany)], Plathow, Christian, University of Tuebingen, Department of Radiology, Tuebingen (Germany)], & Wiebel, Matthias.
Proton MRI appearance of cystic fibrosis: Comparison to CT.
Germany.
https://doi.org/10.1007/S00330-006-0373-4
Puderbach, Michael, Eichinger, Monika, Kauczor, Hans-Ulrich, Gahr, Julie, Mueller, Frank-Michael, Ley, Sebastian, Childrens Hospital, University Heidelberg, Department of Pediatric Radiology, Heidelberg (Germany)], Tuengerthal, Siegfried, Schmaehl, Astrid, Fink, Christian, University of Munich, Medical Center Grosshadern, Institute of Clinical Radiology, Munich (Germany)], Plathow, Christian, University of Tuebingen, Department of Radiology, Tuebingen (Germany)], and Wiebel, Matthias.
2007.
"Proton MRI appearance of cystic fibrosis: Comparison to CT."
Germany.
https://doi.org/10.1007/S00330-006-0373-4.
@misc{etde_20878509,
title = {Proton MRI appearance of cystic fibrosis: Comparison to CT}
author = {Puderbach, Michael, Eichinger, Monika, Kauczor, Hans-Ulrich, Gahr, Julie, Mueller, Frank-Michael, Ley, Sebastian, Childrens Hospital, University Heidelberg, Department of Pediatric Radiology, Heidelberg (Germany)], Tuengerthal, Siegfried, Schmaehl, Astrid, Fink, Christian, University of Munich, Medical Center Grosshadern, Institute of Clinical Radiology, Munich (Germany)], Plathow, Christian, University of Tuebingen, Department of Radiology, Tuebingen (Germany)], and Wiebel, Matthias}
abstractNote = {Cystic fibrosis (CF) is the most frequent inherited disorder leading to premature death in the Caucasian population. As life expectancy is limited by pulmonary complications, repeated imaging [chest X-ray, multislice high-resolution computed tomography (MS-HRCT)] is required in the follow-up. Magnetic resonance imaging (MRI) of the lung parenchyma is a promising new diagnostic tool. Its value for imaging lung changes caused by CF compared with CT is demonstrated. MRI performs well when compared with CT, which serves as the gold standard. Its lack in spatial resolution is obvious, but advantages in contrast and functional assessment compensate for this limitation. Thus, MRI is a reasonable alternative for imaging the CF lung and should be introduced as a radiation-free modality for follow-up studies in CF patients. For further evaluation of the impact of MRI, systematic studies comparing MRI and conventional imaging modalities are necessary. Furthermore, the value of the additional functional MRI (fMRI) information has to be studied, and a scoring system for the morphological and functional aspect of MRI has to be established. (orig.)}
doi = {10.1007/S00330-006-0373-4}
journal = []
issue = {3}
volume = {17}
place = {Germany}
year = {2007}
month = {Mar}
}
title = {Proton MRI appearance of cystic fibrosis: Comparison to CT}
author = {Puderbach, Michael, Eichinger, Monika, Kauczor, Hans-Ulrich, Gahr, Julie, Mueller, Frank-Michael, Ley, Sebastian, Childrens Hospital, University Heidelberg, Department of Pediatric Radiology, Heidelberg (Germany)], Tuengerthal, Siegfried, Schmaehl, Astrid, Fink, Christian, University of Munich, Medical Center Grosshadern, Institute of Clinical Radiology, Munich (Germany)], Plathow, Christian, University of Tuebingen, Department of Radiology, Tuebingen (Germany)], and Wiebel, Matthias}
abstractNote = {Cystic fibrosis (CF) is the most frequent inherited disorder leading to premature death in the Caucasian population. As life expectancy is limited by pulmonary complications, repeated imaging [chest X-ray, multislice high-resolution computed tomography (MS-HRCT)] is required in the follow-up. Magnetic resonance imaging (MRI) of the lung parenchyma is a promising new diagnostic tool. Its value for imaging lung changes caused by CF compared with CT is demonstrated. MRI performs well when compared with CT, which serves as the gold standard. Its lack in spatial resolution is obvious, but advantages in contrast and functional assessment compensate for this limitation. Thus, MRI is a reasonable alternative for imaging the CF lung and should be introduced as a radiation-free modality for follow-up studies in CF patients. For further evaluation of the impact of MRI, systematic studies comparing MRI and conventional imaging modalities are necessary. Furthermore, the value of the additional functional MRI (fMRI) information has to be studied, and a scoring system for the morphological and functional aspect of MRI has to be established. (orig.)}
doi = {10.1007/S00330-006-0373-4}
journal = []
issue = {3}
volume = {17}
place = {Germany}
year = {2007}
month = {Mar}
}