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Role and physiological actions of the mineralo-corticoids; Role et actions physiologiques des mineralo-corticoides

Abstract

This review recalls first of all the history of the discovery of aldosterone; it then defines the concept of mineralo-corticoid on the biological level; the physiological effects of aldosterone are compared with those of desoxycorticosterone, which have been known for a long time. The part played by the mineralo-corticoids in maintaining the hydro-mineral balance is then discussed, particularly in the light of information provided by acute deficiency or primitive hyperaldosteronism; the importance of the correlations linking the post-hypophysis and suprarenal is underlined. The possible mechanisms of the action of mineralo-corticoids on the kidney are discussed in greater detail and a general plan of action is proposed. The physiological regulation of the secretion of mineralo-corticoids is then described, and the respective roles played in this secretion by different factors are discussed (ante-hypophysis, corticoids, plasmatic concentration of electrolytes, volume of extracellular liquids, etc...). Finally, the whole problem investigated is placed within the field of homeostasis (377 bibliographical references). (author) [French] Cette revue de la question rappelle d'abord l'historique de la decouverte de l'aldosterone; elle definit ensuite le concept de mineralo-corticoide sur le plan biologique; les effets physiologiques de l'aldosterone sont compares a ceux connus depuis longtemps de la desoxycorticosterone. Le role joue  More>>
Authors:
Morel, F [1] 
  1. Commissariat a l'Energie Atomique, Saclay (France). Centre d'Etudes Nucleaires
Publication Date:
Jul 01, 1958
Product Type:
Technical Report
Report Number:
CEA-R-790
Resource Relation:
Other Information: 377 refs
Subject:
60 APPLIED LIFE SCIENCES; ADRENAL GLANDS; ALDOSTERONE; BIOLOGICAL FUNCTIONS; BLOOD PLASMA; CELL MEMBRANES; ELECTROLYTES; EXCRETION; EXTRACELLULAR SPACE; GLOMERULI; HOMEOSTASIS; MEMBRANE TRANSPORT; OSMOSIS; PHYSIOLOGY; PITUITARY GLAND; POTASSIUM IONS; SECRETION; SODIUM IONS; STRUCTURE-ACTIVITY RELATIONSHIPS; URINE; VASOPRESSIN
OSTI ID:
20877844
Research Organizations:
CEA Saclay, 91 - Gif-sur-Yvette (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR07R0790045557
Availability:
Available from INIS in electronic form
Submitting Site:
FRN
Size:
42 pages
Announcement Date:
Jun 15, 2007

Citation Formats

Morel, F. Role and physiological actions of the mineralo-corticoids; Role et actions physiologiques des mineralo-corticoides. France: N. p., 1958. Web.
Morel, F. Role and physiological actions of the mineralo-corticoids; Role et actions physiologiques des mineralo-corticoides. France.
Morel, F. 1958. "Role and physiological actions of the mineralo-corticoids; Role et actions physiologiques des mineralo-corticoides." France.
@misc{etde_20877844,
title = {Role and physiological actions of the mineralo-corticoids; Role et actions physiologiques des mineralo-corticoides}
author = {Morel, F}
abstractNote = {This review recalls first of all the history of the discovery of aldosterone; it then defines the concept of mineralo-corticoid on the biological level; the physiological effects of aldosterone are compared with those of desoxycorticosterone, which have been known for a long time. The part played by the mineralo-corticoids in maintaining the hydro-mineral balance is then discussed, particularly in the light of information provided by acute deficiency or primitive hyperaldosteronism; the importance of the correlations linking the post-hypophysis and suprarenal is underlined. The possible mechanisms of the action of mineralo-corticoids on the kidney are discussed in greater detail and a general plan of action is proposed. The physiological regulation of the secretion of mineralo-corticoids is then described, and the respective roles played in this secretion by different factors are discussed (ante-hypophysis, corticoids, plasmatic concentration of electrolytes, volume of extracellular liquids, etc...). Finally, the whole problem investigated is placed within the field of homeostasis (377 bibliographical references). (author) [French] Cette revue de la question rappelle d'abord l'historique de la decouverte de l'aldosterone; elle definit ensuite le concept de mineralo-corticoide sur le plan biologique; les effets physiologiques de l'aldosterone sont compares a ceux connus depuis longtemps de la desoxycorticosterone. Le role joue par les mineralo-corticoides dans le maintien de la balance hydrominerale est ensuite discute, notamment a la lumiere des informations fournies par l'insuffisance aigue ou l'hyperaldosteronisme primitif; l'importance des correlations liant posthypophyse et surrenale est soulignee. Les mecanismes possibles de l'action des mineralo-corticoides sur le rein sont discutes avec davantage de details et un schema general d'action est propose. La regulation physiologique de la secretion des mineralo-corticoides est ensuite exposee et les roles respectifs joues dans cette secretion par differents facteurs sont discutes (antehypophyse, corticoides, concentration plasmatique des electrolytes, volume des liquides extracellulaires, etc...). Enfin, l'ensemble du probleme etudie est place dans le cadre de l'homeostasie (377 references bibliographiques). (auteur)}
place = {France}
year = {1958}
month = {Jul}
}