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Spectrum and immediate outcome of seizures in neonates

Journal Article:

Abstract

To determine the frequency, etiology, the clinical types, and outcome of seizures in neonates during the course of stay in the neonatal unit. All neonates (1-28 days) presented with seizures during that period were included in the study. Their detailed history, physical examination, and appropriate investigations were recorded on a study proforma. Out of a total 680 patients, 100 patients presented with the seizures; this comprises the frequency of 14.7%. Male to female ratio was 2.1:1. Regarding gestational age, 65% were full-term, 31% were pre-term, and 4% were post-term. Regarding etiology, 40% patients had birth asphyxia; 14% had hypoglycemia; 12% were due to hypocalcaemia, 5% were due to intracranial hemorrhage (ICH), 4% had malformation, 10 % had infection /neonatal sepsis, and in 12%, the etiology was kernicterus. Among the patients with seizures, 45% were completely recovered and discharged and 15% patients had neurological deficit at the time of discharge. From the hospitalized 100 patients, 22% expired. The critical factors for the outcome were etiology, gestational age, birth weight, APGAR score, and clinical characteristics. Generally, birth asphyxia had poor, while metabolic causes had good prognosis. (author)
Authors:
Memon, S; Mohd, M; Hussain, A [1] 
  1. Liaquat Univ. of Medical and Health Sciences, Hyderabad (Pakistan). Dept. of Paediatrics
Publication Date:
Nov 15, 2006
Product Type:
Journal Article
Resource Relation:
Journal Name: JCPSP. Journal of the College of Physicians and Surgeons Pakistan; Journal Volume: 16; Journal Issue: 11
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DIAGNOSIS; ETIOLOGY; HEMORRHAGE; ISCHEMIA; MORTALITY; NEONATES; PATIENTS
OSTI ID:
20873007
Country of Origin:
Pakistan
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 1022-386X; TRN: PK0700173040992
Submitting Site:
INIS
Size:
page(s) 717-720
Announcement Date:
Jun 06, 2007

Journal Article:

Citation Formats

Memon, S, Mohd, M, and Hussain, A. Spectrum and immediate outcome of seizures in neonates. Pakistan: N. p., 2006. Web.
Memon, S, Mohd, M, & Hussain, A. Spectrum and immediate outcome of seizures in neonates. Pakistan.
Memon, S, Mohd, M, and Hussain, A. 2006. "Spectrum and immediate outcome of seizures in neonates." Pakistan.
@misc{etde_20873007,
title = {Spectrum and immediate outcome of seizures in neonates}
author = {Memon, S, Mohd, M, and Hussain, A}
abstractNote = {To determine the frequency, etiology, the clinical types, and outcome of seizures in neonates during the course of stay in the neonatal unit. All neonates (1-28 days) presented with seizures during that period were included in the study. Their detailed history, physical examination, and appropriate investigations were recorded on a study proforma. Out of a total 680 patients, 100 patients presented with the seizures; this comprises the frequency of 14.7%. Male to female ratio was 2.1:1. Regarding gestational age, 65% were full-term, 31% were pre-term, and 4% were post-term. Regarding etiology, 40% patients had birth asphyxia; 14% had hypoglycemia; 12% were due to hypocalcaemia, 5% were due to intracranial hemorrhage (ICH), 4% had malformation, 10 % had infection /neonatal sepsis, and in 12%, the etiology was kernicterus. Among the patients with seizures, 45% were completely recovered and discharged and 15% patients had neurological deficit at the time of discharge. From the hospitalized 100 patients, 22% expired. The critical factors for the outcome were etiology, gestational age, birth weight, APGAR score, and clinical characteristics. Generally, birth asphyxia had poor, while metabolic causes had good prognosis. (author)}
journal = {JCPSP. Journal of the College of Physicians and Surgeons Pakistan}
issue = {11}
volume = {16}
place = {Pakistan}
year = {2006}
month = {Nov}
}