You need JavaScript to view this

Brain imaging and autism

Conference:

Abstract

Autism is a neuro-developmental disorder with a range of clinical presentations, from mild to severe, referred to as autism spectrum disorders (ASD). The most common clinical ASD sign is social interaction impairment, which is associated with verbal and non-verbal communication deficits and stereotyped and obsessive behaviors. Thanks to recent brain imaging studies, scientists are getting a better idea of the neural circuits involved in ASD. Indeed, functional brain imaging, such as positron emission tomography (PET), single positron emission tomograph y (SPECT) and functional MRI (fMRI) have opened a new perspective to study normal and pathological brain functions. Three independent studies have found anatomical and rest functional temporal abnormalities. These anomalies are localized in the superior temporal sulcus bilaterally which are critical for perception of key social stimuli. In addition, functional studies have shown hypo-activation of most areas implicated in social perception (face and voice perception) and social cognition (theory of mind). These data suggest an abnormal functioning of the social brain network. The understanding of such crucial abnormal mechanism may drive the elaboration of new and more adequate social re-educative strategies in autism. (author)
Authors:
Zilbovicius, M [1] 
  1. Service Hospitalier Frederic Joliot (CEA/DSV/DRM), INSERM CEA 0205, 91 - Orsay (France)
Publication Date:
Jul 01, 2006
Product Type:
Conference
Resource Relation:
Conference: 6. Japan-France workshop on radiobiology and isotopic imaging, Paris (France), 19-22 Jun 2006; Related Information: In: Radiobiology and isotopic imaging, 123 pages.
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BEHAVIOR; BRAIN; CENTRAL NERVOUS SYSTEM; IMAGES; MENTAL DISORDERS; NERVOUS SYSTEM DISEASES; NMR IMAGING; POSITRON COMPUTED TOMOGRAPHY; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
OSTI ID:
20859017
Research Organizations:
CEA Saclay, 91 - Gif-sur-Yvette (France); National Institute of Radiological Sciences, Inage-ku, Chiba (Japan)
Country of Origin:
France
Language:
English
Other Identifying Numbers:
Other: ISBN 2-7272-0224-5; TRN: FR0700125021962
Submitting Site:
FRN
Size:
page(s) 85
Announcement Date:
Apr 18, 2007

Conference:

Citation Formats

Zilbovicius, M. Brain imaging and autism. France: N. p., 2006. Web.
Zilbovicius, M. Brain imaging and autism. France.
Zilbovicius, M. 2006. "Brain imaging and autism." France.
@misc{etde_20859017,
title = {Brain imaging and autism}
author = {Zilbovicius, M}
abstractNote = {Autism is a neuro-developmental disorder with a range of clinical presentations, from mild to severe, referred to as autism spectrum disorders (ASD). The most common clinical ASD sign is social interaction impairment, which is associated with verbal and non-verbal communication deficits and stereotyped and obsessive behaviors. Thanks to recent brain imaging studies, scientists are getting a better idea of the neural circuits involved in ASD. Indeed, functional brain imaging, such as positron emission tomography (PET), single positron emission tomograph y (SPECT) and functional MRI (fMRI) have opened a new perspective to study normal and pathological brain functions. Three independent studies have found anatomical and rest functional temporal abnormalities. These anomalies are localized in the superior temporal sulcus bilaterally which are critical for perception of key social stimuli. In addition, functional studies have shown hypo-activation of most areas implicated in social perception (face and voice perception) and social cognition (theory of mind). These data suggest an abnormal functioning of the social brain network. The understanding of such crucial abnormal mechanism may drive the elaboration of new and more adequate social re-educative strategies in autism. (author)}
place = {France}
year = {2006}
month = {Jul}
}