Abstract
The recent discovery of the tuberculostatic properties of the hydrazide of isonicotinic acid (so-called 'Isoniazide', 'Rimifon') has raised considerably its interest, as for metabolic studies which it is more interesting to have it labelled with {sup 14}C. We describe in this report the chemical synthesis of {sup 14}C carboxyl labelled isoniazide which were done in the pyridine ring to highlight his metabolic function on the Koch's bacillus. (M.B.)
Pichat, I;
Baret, C;
Audinot, M;
Herbert, M;
Lambin, J
[1]
- Commissariat a l'Energie Atomique, Lab. du Fort de Chatillon, Fontenay-aux-Roses (France). Centre d'Etudes Nucleaires
Citation Formats
Pichat, I, Baret, C, Audinot, M, Herbert, M, and Lambin, J.
Some chemical synthesis of {sup 14}C labelled compounds of pharmaceutical or biological interest.
France: N. p.,
1955.
Web.
Pichat, I, Baret, C, Audinot, M, Herbert, M, & Lambin, J.
Some chemical synthesis of {sup 14}C labelled compounds of pharmaceutical or biological interest.
France.
Pichat, I, Baret, C, Audinot, M, Herbert, M, and Lambin, J.
1955.
"Some chemical synthesis of {sup 14}C labelled compounds of pharmaceutical or biological interest."
France.
@misc{etde_20854619,
title = {Some chemical synthesis of {sup 14}C labelled compounds of pharmaceutical or biological interest}
author = {Pichat, I, Baret, C, Audinot, M, Herbert, M, and Lambin, J}
abstractNote = {The recent discovery of the tuberculostatic properties of the hydrazide of isonicotinic acid (so-called 'Isoniazide', 'Rimifon') has raised considerably its interest, as for metabolic studies which it is more interesting to have it labelled with {sup 14}C. We describe in this report the chemical synthesis of {sup 14}C carboxyl labelled isoniazide which were done in the pyridine ring to highlight his metabolic function on the Koch's bacillus. (M.B.)}
place = {France}
year = {1955}
month = {Jul}
}
title = {Some chemical synthesis of {sup 14}C labelled compounds of pharmaceutical or biological interest}
author = {Pichat, I, Baret, C, Audinot, M, Herbert, M, and Lambin, J}
abstractNote = {The recent discovery of the tuberculostatic properties of the hydrazide of isonicotinic acid (so-called 'Isoniazide', 'Rimifon') has raised considerably its interest, as for metabolic studies which it is more interesting to have it labelled with {sup 14}C. We describe in this report the chemical synthesis of {sup 14}C carboxyl labelled isoniazide which were done in the pyridine ring to highlight his metabolic function on the Koch's bacillus. (M.B.)}
place = {France}
year = {1955}
month = {Jul}
}