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Action of diode laser (830 nm) on cutaneous wound healing process: biometrical and histological study in rats; Acao do diodo laser emitindo em 830 nm, sobre o processo de cicatrizacao de lesoes cutaneas: estudo biometrico e histologico em ratos

Abstract

In this research, it was analyzed the acceleration of the healing process of cutaneous lesions in mice, using a diode laser emitting in 830 nm. The 64 selected animals in this study were randomically divided into four groups of 16 animals each (G1, G2, G3 and G4). Biometric and histological comparisons were accomplished in the following periods: 3, 7 and 14 days after the surgery and laser application. Three laser irradiation configurations were used: a punctual contact (G2) and two non-contact and uniform (G3 and G4). For group G2, the laser intensity was 428 mW/cm{sup 2} , and for groups G3 and G4 it was 53 mW/cm{sup 2}. The total doses were D = 3 J/cm{sup 2} for groups G2 and G4, and D = 1,3 J/cm{sup 2} for G3. The first group, G1, was considered control and thus not submitted to any treatment after the surgery. All irradiated lesions presented acceleration of the healing process with regard to the control group. However, our results clearly indicate that the smaller laser intensity (uniform irradiation) leaded to the best results. On the other hand, the smaller used dose also leaded to the more significant and expressive results. The combination of the  More>>
Publication Date:
Jul 01, 2001
Product Type:
Thesis/Dissertation
Report Number:
INIS-BR-4040
Resource Relation:
Other Information: TH: Dissertacao (M.Sc.); 61 refs., 34 figs., 7 tabs
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; DOSE-RESPONSE RELATIONSHIPS; GALLIUM ARSENIDES; HEALING; HISTOLOGY; LASER RADIATION; RATS; SEMICONDUCTOR LASERS; SKIN; WOUNDS
OSTI ID:
20761967
Research Organizations:
Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil); Sao Paulo Univ., SP (Brazil). Faculdade de Odontologia
Country of Origin:
Brazil
Language:
Portuguese
Other Identifying Numbers:
TRN: BR0645459069019
Availability:
Available from INIS in electronic form
Submitting Site:
BRN
Size:
88 pages
Announcement Date:
Sep 06, 2006

Citation Formats

Rezende, Sandra Bastos. Action of diode laser (830 nm) on cutaneous wound healing process: biometrical and histological study in rats; Acao do diodo laser emitindo em 830 nm, sobre o processo de cicatrizacao de lesoes cutaneas: estudo biometrico e histologico em ratos. Brazil: N. p., 2001. Web.
Rezende, Sandra Bastos. Action of diode laser (830 nm) on cutaneous wound healing process: biometrical and histological study in rats; Acao do diodo laser emitindo em 830 nm, sobre o processo de cicatrizacao de lesoes cutaneas: estudo biometrico e histologico em ratos. Brazil.
Rezende, Sandra Bastos. 2001. "Action of diode laser (830 nm) on cutaneous wound healing process: biometrical and histological study in rats; Acao do diodo laser emitindo em 830 nm, sobre o processo de cicatrizacao de lesoes cutaneas: estudo biometrico e histologico em ratos." Brazil.
@misc{etde_20761967,
title = {Action of diode laser (830 nm) on cutaneous wound healing process: biometrical and histological study in rats; Acao do diodo laser emitindo em 830 nm, sobre o processo de cicatrizacao de lesoes cutaneas: estudo biometrico e histologico em ratos}
author = {Rezende, Sandra Bastos}
abstractNote = {In this research, it was analyzed the acceleration of the healing process of cutaneous lesions in mice, using a diode laser emitting in 830 nm. The 64 selected animals in this study were randomically divided into four groups of 16 animals each (G1, G2, G3 and G4). Biometric and histological comparisons were accomplished in the following periods: 3, 7 and 14 days after the surgery and laser application. Three laser irradiation configurations were used: a punctual contact (G2) and two non-contact and uniform (G3 and G4). For group G2, the laser intensity was 428 mW/cm{sup 2} , and for groups G3 and G4 it was 53 mW/cm{sup 2}. The total doses were D = 3 J/cm{sup 2} for groups G2 and G4, and D = 1,3 J/cm{sup 2} for G3. The first group, G1, was considered control and thus not submitted to any treatment after the surgery. All irradiated lesions presented acceleration of the healing process with regard to the control group. However, our results clearly indicate that the smaller laser intensity (uniform irradiation) leaded to the best results. On the other hand, the smaller used dose also leaded to the more significant and expressive results. The combination of the intensity value of 53 mW/cm{sup 2} and the dose of 1,3 J/cm{sup 2} leaded to optimal results, regarding the Biometric and histological analysis, presenting faster lesion contraction, quicker neoformation of epithelial and conjunctive tissue (with more collagen fibers ). (author)}
place = {Brazil}
year = {2001}
month = {Jul}
}