You need JavaScript to view this

A new biological method for preparing certain sulphurated substances labelled with S{sup 35}; Methode nouvelle de preparation par voie biologique de quelques substances soufrees marquees au soufre-35

Abstract

Previous investigations have shown that the yolk-sac of embryonic bird's eggs can be used to produce the following reactions: (a) reduction of sulphate to sulphite; (b) fixation of the sulphite on the carbon chain produced by the desulf-hydration of l-cysteine, with formation of l-cysteic acid; (c) decarboxylation of the l-cysteine acid into taurine. The enzymatic system which causes reaction (b) has been purified. It also acts as a catalyst in the sulphur-exchange between the cysteine and the mineral sulphide. The authors have utilized these data in preparing sulphurated substances labelled with S{sup 35}: taurine S{sup 35}, l-cysteine S{sup 35} and l-cysteic acid S{sup 35}. For each of the three, they discuss the chemical reactions involved, the methods of preparation, the experimental conditions of extraction and purity-control, together with the yields and specific activities obtained. (authors) [French] Des travaux anterieurs ont montre l'aptitude du sac vitellin d'oeufs embryonn d'oiseaux a realiser les reactions suivantes: a) reduction du sulfate en sulfite, b) fixation du sulfite sur la chaine carbonee issue de la desulfhydration de la L-cysteine avec formation de l'acide L-cysteique. c) decarboxylation de l 'acide L-cysteique en taurine. Le systeme enzymatique responsable de la reaction b a ete purifie; il catalyse  More>>
Authors:
Chapeville, F; Maier-Huser, H; Fromageot, P [1] 
  1. Commissariat a l'Energie Atomique, Saclay (France). Centre d'Etudes Nucleaires
Publication Date:
Jul 01, 1962
Product Type:
Technical Report
Report Number:
CEA-R-2181
Resource Relation:
Other Information: 6 refs
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; BIOSYNTHESIS; CHEMICAL PREPARATION; CYSTEINE; CYSTINE; EGGS; LABELLED COMPOUNDS; LABELLING; SULFUR 35; TAURINE
OSTI ID:
20754726
Research Organizations:
CEA Saclay, 91 - Gif-sur-Yvette (France)
Country of Origin:
France
Language:
French
Other Identifying Numbers:
TRN: FR06R2181062521
Availability:
Available from INIS in electronic form
Submitting Site:
FRN
Size:
10 pages
Announcement Date:
Aug 14, 2006

Citation Formats

Chapeville, F, Maier-Huser, H, and Fromageot, P. A new biological method for preparing certain sulphurated substances labelled with S{sup 35}; Methode nouvelle de preparation par voie biologique de quelques substances soufrees marquees au soufre-35. France: N. p., 1962. Web.
Chapeville, F, Maier-Huser, H, & Fromageot, P. A new biological method for preparing certain sulphurated substances labelled with S{sup 35}; Methode nouvelle de preparation par voie biologique de quelques substances soufrees marquees au soufre-35. France.
Chapeville, F, Maier-Huser, H, and Fromageot, P. 1962. "A new biological method for preparing certain sulphurated substances labelled with S{sup 35}; Methode nouvelle de preparation par voie biologique de quelques substances soufrees marquees au soufre-35." France.
@misc{etde_20754726,
title = {A new biological method for preparing certain sulphurated substances labelled with S{sup 35}; Methode nouvelle de preparation par voie biologique de quelques substances soufrees marquees au soufre-35}
author = {Chapeville, F, Maier-Huser, H, and Fromageot, P}
abstractNote = {Previous investigations have shown that the yolk-sac of embryonic bird's eggs can be used to produce the following reactions: (a) reduction of sulphate to sulphite; (b) fixation of the sulphite on the carbon chain produced by the desulf-hydration of l-cysteine, with formation of l-cysteic acid; (c) decarboxylation of the l-cysteine acid into taurine. The enzymatic system which causes reaction (b) has been purified. It also acts as a catalyst in the sulphur-exchange between the cysteine and the mineral sulphide. The authors have utilized these data in preparing sulphurated substances labelled with S{sup 35}: taurine S{sup 35}, l-cysteine S{sup 35} and l-cysteic acid S{sup 35}. For each of the three, they discuss the chemical reactions involved, the methods of preparation, the experimental conditions of extraction and purity-control, together with the yields and specific activities obtained. (authors) [French] Des travaux anterieurs ont montre l'aptitude du sac vitellin d'oeufs embryonn d'oiseaux a realiser les reactions suivantes: a) reduction du sulfate en sulfite, b) fixation du sulfite sur la chaine carbonee issue de la desulfhydration de la L-cysteine avec formation de l'acide L-cysteique. c) decarboxylation de l 'acide L-cysteique en taurine. Le systeme enzymatique responsable de la reaction b a ete purifie; il catalyse aussi l'echange du soufre de la cysteine avec celui du sulfure mineral. Les auteurs ont utilise ces donnees pour la preparation de substances soufrees marquees au {sup 35}S: taurine {sup 35}S, L-cysteine{sup 35} et acide L-cysteique {sup 35}S. Pour chacun de ces trois corps, ils decrivent les reactions chimiques mises en jeu, les modes operatoires de fabrication, les conditions experimentales d'extraction et de controle de la purete, ainsi que les resultats obtenus tant pour les rendements que pour les activites specifiques obtenues. (auteurs)}
place = {France}
year = {1962}
month = {Jul}
}