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Clinical assessment of transcatheter closure of patent ductus arteriosus with severe pulmonary hypertention using Amplatzer occluder

Journal Article:

Abstract

Objective: To evaluate the application of transcatheter closure of patent ductus arteriosus (PDA) with severe pulmonary hypertention using the Amplatzer occluder device. Methods: Fifty-one cases of PDA with severe pulmonary hypertention were treated by transcatheter closure with Amplatzer occluder. Patients mean age was 9.4 years (ranging 3 months to 60 years) and the mean weight was (18.7 {+-} 13.8) kg (ranging 5.0 to 65.0 kg). The mean PDA diameter at its narrowest segment was (7.0 {+-} 2.4) (ranging 3.0 to 15.0) mm. The achievement of permanent transcatheter closure was decided according to the change of the pulmonary arterial pressure, aortic pressure and oxygen saturation. Results: The devices were successfully placed in all patients except one failure owing to the resistance of pulmonary hypertention. The systolic pulmonary pressure decreased from (84.7 {+-} 13.5) (range 70 to 137) to mmHg to (46.1 {+-} 14.9) (24 to 109) mmHg, and the mean pulmonary pressure decreased from (65.0 {+-} 11.5) (42 to 97) mmHg to (31.3 {+-} 11.6) (14 to 69) mmHg. Complete angiographic closure was seen 10 minutes after the device deployment in 30 out of 50 patients (60%), while trivial to small leak was present in 20 (40%). Complete echocardiographic closure was  More>>
Authors:
Xiumin, Han; Xianyang, Zhu; Yuwei, Zhang; Yan, Jin; Dong'an, Deng; Chanju, Hou; Wei, Quan [1] 
  1. Shenyang General Hospital, PLA, Shenyang (China)
Publication Date:
Apr 01, 2004
Product Type:
Journal Article
Resource Relation:
Journal Name: Journal of Interventional Radiology; Journal Volume: 13; Journal Issue: 2; Other Information: 7 refs
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; AORTA; ARTERIES; BIOMEDICAL RADIOGRAPHY; CARDIOVASCULAR DISEASES; HEART; IMPLANTS; LUNGS; MEDICAL SURVEILLANCE; SURGERY; ULTRASONOGRAPHY
OSTI ID:
20665560
Country of Origin:
China
Language:
Chinese
Other Identifying Numbers:
Journal ID: ISSN 1008-794X; TRN: CN0502413103548
Submitting Site:
INIS
Size:
page(s) 117-119
Announcement Date:
Dec 08, 2005

Journal Article:

Citation Formats

Xiumin, Han, Xianyang, Zhu, Yuwei, Zhang, Yan, Jin, Dong'an, Deng, Chanju, Hou, and Wei, Quan. Clinical assessment of transcatheter closure of patent ductus arteriosus with severe pulmonary hypertention using Amplatzer occluder. China: N. p., 2004. Web.
Xiumin, Han, Xianyang, Zhu, Yuwei, Zhang, Yan, Jin, Dong'an, Deng, Chanju, Hou, & Wei, Quan. Clinical assessment of transcatheter closure of patent ductus arteriosus with severe pulmonary hypertention using Amplatzer occluder. China.
Xiumin, Han, Xianyang, Zhu, Yuwei, Zhang, Yan, Jin, Dong'an, Deng, Chanju, Hou, and Wei, Quan. 2004. "Clinical assessment of transcatheter closure of patent ductus arteriosus with severe pulmonary hypertention using Amplatzer occluder." China.
@misc{etde_20665560,
title = {Clinical assessment of transcatheter closure of patent ductus arteriosus with severe pulmonary hypertention using Amplatzer occluder}
author = {Xiumin, Han, Xianyang, Zhu, Yuwei, Zhang, Yan, Jin, Dong'an, Deng, Chanju, Hou, and Wei, Quan}
abstractNote = {Objective: To evaluate the application of transcatheter closure of patent ductus arteriosus (PDA) with severe pulmonary hypertention using the Amplatzer occluder device. Methods: Fifty-one cases of PDA with severe pulmonary hypertention were treated by transcatheter closure with Amplatzer occluder. Patients mean age was 9.4 years (ranging 3 months to 60 years) and the mean weight was (18.7 {+-} 13.8) kg (ranging 5.0 to 65.0 kg). The mean PDA diameter at its narrowest segment was (7.0 {+-} 2.4) (ranging 3.0 to 15.0) mm. The achievement of permanent transcatheter closure was decided according to the change of the pulmonary arterial pressure, aortic pressure and oxygen saturation. Results: The devices were successfully placed in all patients except one failure owing to the resistance of pulmonary hypertention. The systolic pulmonary pressure decreased from (84.7 {+-} 13.5) (range 70 to 137) to mmHg to (46.1 {+-} 14.9) (24 to 109) mmHg, and the mean pulmonary pressure decreased from (65.0 {+-} 11.5) (42 to 97) mmHg to (31.3 {+-} 11.6) (14 to 69) mmHg. Complete angiographic closure was seen 10 minutes after the device deployment in 30 out of 50 patients (60%), while trivial to small leak was present in 20 (40%). Complete echocardiographic closure was demonstrated in 49 out of 50 patients (98%) at 10 min, and 100% at 6-month follow-up in all patients. There were no PDA recanalization and migration of devices after the complete occlusion during following up. Conclusion: Transcatheter closure of patent ductus arteriosus with severe pulmonary hypertention by using the Amplatzer occluder is a safe and effective interventional method with excellent short-term and middle-term results. (authors)}
journal = {Journal of Interventional Radiology}
issue = {2}
volume = {13}
place = {China}
year = {2004}
month = {Apr}
}