You need JavaScript to view this
ETDEWEB   /       /    Enhancement of tumor response by Wortmannin in C3H/HeJ hepatocarcinoma

Enhancement of tumor response by Wortmannin in C3H/HeJ hepatocarcinoma

Conference:

SAVE / SHARE

XML RIS EndNote CSV/Excel JSON

Abstract

Phosphatidylinositol 3-kinase (PI3K) has been known as one of key molecules in survival signaling. PI3K signaling is an important intracellular mediator which is involved in multiple cellular functions including proliferation, differentiation, anti-apoptosis, tumorigenesis, and angiogenesis. Inhibition of this molecule might be used in cancer treatment. Wortmannin has been reported to be an efficient radiosensitizer. The objective of this study was to explore whether PI3K inhibitor, Wortmannin, could potentiate the antitumor effect of radiation in vivo, particularly on radioresistant murine tumor.
Authors:
Kim, Won Woo; Kim, Ji Young; Seong, Jin Sil [1] 
  1. Yonsei University, Seoul (Korea, Republic of)
Publication Date:
Jul 01, 2004
Product Type:
Conference
Resource Relation:
Conference: 2004 autumn meeting of the KNS, Yongpyong (Korea, Republic of), 28-29 Oct 2004; Other Information: 6 refs, 3 figs; Related Information: In: Proceedings of the KNS autumn meeting, 1466 pages.
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; APOPTOSIS; CARCINOMAS; IN VIVO; RADIOSENSITIVITY; RADIOSENSITIZERS; RADIOTHERAPY; SIGNALS
OSTI ID:
20664710
Research Organizations:
Korean Nuclear Society, Taejon (Korea, Republic of)
Country of Origin:
Korea, Republic of
Language:
English
Other Identifying Numbers:
TRN: KR0502900102617
Availability:
Available from KNS, Taejon (KR)
Submitting Site:
KRN
Size:
page(s) 1206-1207
Announcement Date:
Dec 12, 2005

Conference:

SAVE / SHARE

XML RIS EndNote CSV/Excel JSON

Citation Formats

Kim, Won Woo, Kim, Ji Young, and Seong, Jin Sil. Enhancement of tumor response by Wortmannin in C3H/HeJ hepatocarcinoma. Korea, Republic of: N. p., 2004. Web.
Kim, Won Woo, Kim, Ji Young, & Seong, Jin Sil. Enhancement of tumor response by Wortmannin in C3H/HeJ hepatocarcinoma. Korea, Republic of.
Kim, Won Woo, Kim, Ji Young, and Seong, Jin Sil. 2004. "Enhancement of tumor response by Wortmannin in C3H/HeJ hepatocarcinoma." Korea, Republic of.
@misc{etde_20664710,
title = {Enhancement of tumor response by Wortmannin in C3H/HeJ hepatocarcinoma}
 author = {Kim, Won Woo, Kim, Ji Young, and Seong, Jin Sil}
 abstractNote = {Phosphatidylinositol 3-kinase (PI3K) has been known as one of key molecules in survival signaling. PI3K signaling is an important intracellular mediator which is involved in multiple cellular functions including proliferation, differentiation, anti-apoptosis, tumorigenesis, and angiogenesis. Inhibition of this molecule might be used in cancer treatment. Wortmannin has been reported to be an efficient radiosensitizer. The objective of this study was to explore whether PI3K inhibitor, Wortmannin, could potentiate the antitumor effect of radiation in vivo, particularly on radioresistant murine tumor.}
 place = {Korea, Republic of}
 year = {2004}
 month = {Jul}
 }