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Normal development of brainstem in childhood. Measurement of the area on mid-sagittal MR imaging

Journal Article:

Abstract

Developmental abnormality of brainstem is shown in pediatric patients with mental retardation, autism, periventricular leukomalacia, neurodegenerative disease, and so on. Our purpose here is to clarify the normal developmental pattern of the brainstem. We measured the area of tectum, midbrain tegmentum, pons, basis pontis and pontine tegmentum on mid-sagittal MR images in 111 children (newborn to 20 year old). Different growth patterns were shown in all parts of the brainstem. Tectum showed a subtle increase in area from the newborn to adult period, while midbrain tegmentum and pontine tegmenturn showed a mild and gradual increase in area. Pons and pontine tegmentum showed a rapid and prominent increase in area from newborn to infant period and gradual increase in area until the adult period. These different growth patterns seemed to be consistent with differences in the myelination cycles of the neuronal fibers, maturation of the nuclei and proliferation of glial cells in each part of the brainstem. Mid-sagittal MR imaging of the head is accurate and reproducible and is used conveniently in routine head MR study, making it very useful for the diagnosis of many central nervous diseases and anomalies. We believe that this new milestone provided in this study will  More>>
Authors:
Kutomi, Kimiko [1] 
  1. Teikyo Univ., Tokyo (Japan). Faculty of Medicine
Publication Date:
May 01, 2005
Product Type:
Journal Article
Resource Relation:
Journal Name: Teikyo Igaku Zasshi; Journal Volume: 28; Journal Issue: 3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ADULTS; ANIMAL GROWTH; CEREBRUM; INFANTS; MORPHOLOGICAL CHANGES; NMR IMAGING; SEX DEPENDENCE; SIZE; SPIN-LATTICE RELAXATION
OSTI ID:
20661370
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: ISSN 0387-5547; TIGZDZ; TRN: JP0503922099915
Submitting Site:
INIS
Size:
page(s) 159-168
Announcement Date:
Dec 08, 2005

Journal Article:

Citation Formats

Kutomi, Kimiko. Normal development of brainstem in childhood. Measurement of the area on mid-sagittal MR imaging. Japan: N. p., 2005. Web.
Kutomi, Kimiko. Normal development of brainstem in childhood. Measurement of the area on mid-sagittal MR imaging. Japan.
Kutomi, Kimiko. 2005. "Normal development of brainstem in childhood. Measurement of the area on mid-sagittal MR imaging." Japan.
@misc{etde_20661370,
title = {Normal development of brainstem in childhood. Measurement of the area on mid-sagittal MR imaging}
author = {Kutomi, Kimiko}
abstractNote = {Developmental abnormality of brainstem is shown in pediatric patients with mental retardation, autism, periventricular leukomalacia, neurodegenerative disease, and so on. Our purpose here is to clarify the normal developmental pattern of the brainstem. We measured the area of tectum, midbrain tegmentum, pons, basis pontis and pontine tegmentum on mid-sagittal MR images in 111 children (newborn to 20 year old). Different growth patterns were shown in all parts of the brainstem. Tectum showed a subtle increase in area from the newborn to adult period, while midbrain tegmentum and pontine tegmenturn showed a mild and gradual increase in area. Pons and pontine tegmentum showed a rapid and prominent increase in area from newborn to infant period and gradual increase in area until the adult period. These different growth patterns seemed to be consistent with differences in the myelination cycles of the neuronal fibers, maturation of the nuclei and proliferation of glial cells in each part of the brainstem. Mid-sagittal MR imaging of the head is accurate and reproducible and is used conveniently in routine head MR study, making it very useful for the diagnosis of many central nervous diseases and anomalies. We believe that this new milestone provided in this study will be helpful in distinguishing normal children from those that have neurodegenerative disorders. (author)}
journal = {Teikyo Igaku Zasshi}
issue = {3}
volume = {28}
place = {Japan}
year = {2005}
month = {May}
}