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The cancerogenicity of fall out nuclides

Abstract

One of the more than 400 radionuclides which are produced in a nuclear reactor only a few of these have features such as solubility, long physical and biological half life and specific affinity to a certain tissue - which could classify them as biologically hazardous. Therefore in this context only radio-iodine-cesium and -strontium are discussed briefly as regards their biological effects. It is pointed out that tumours are not easily induced by radioiodine in experimental systems and that this is also valid for humans. Radiocesium is not very extensively studied experimentally as regards its biological action but available data indicate a low - if any - cancerogenic potentiality in contrast to radiostrontium with its high yield of tumours in various tissues. The extrapolation of experimental data to man as well as a comparison between cancerogenic irradiation doses between man and animals are discussed and considered as a necessity because of the ill defined irradiation situation and data which are connected with most accidental exposure of man. Furthermore it is also pointed out that the general idea that irradiation risks always are represented by a linear dose-effect relationship in most cases has no support from scientific data and therefore give an  More>>
Authors:
Nilsson, Agnar [1] 
  1. Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Science, Uppsala (Sweden)
Publication Date:
Jul 01, 1986
Product Type:
Conference
Report Number:
INIS-XA-C-069
Resource Relation:
Conference: International round table conference 'Accidental radiation contamination of food of animal origin, Stockholm (Sweden), 26-29 Jan 1987; Other Information: 18 refs, 4 tabs; Related Information: In: Report on international round table conference 'Accidental radiation contamination of food of animal origin'. Vol.II (Working papers), 214 pages.
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; 54 ENVIRONMENTAL SCIENCES; BIOLOGICAL RADIATION EFFECTS; CARCINOGENESIS; DOSE-RESPONSE RELATIONSHIPS; NEOPLASMS; ONCOGENIC TRANSFORMATIONS; RADIATION HAZARDS; RADIATION PROTECTION
OSTI ID:
20637404
Research Organizations:
World Association of Veterinary Food Hygienists, Institute of Veterinary Medicine, Robert von Ostertag-Institute, Berlin (Germany)
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
TRN: XA04C0172080766
Availability:
Available from INIS in electronic form
Submitting Site:
INIS
Size:
13 pages
Announcement Date:
Nov 07, 2005

Citation Formats

Nilsson, Agnar. The cancerogenicity of fall out nuclides. IAEA: N. p., 1986. Web.
Nilsson, Agnar. The cancerogenicity of fall out nuclides. IAEA.
Nilsson, Agnar. 1986. "The cancerogenicity of fall out nuclides." IAEA.
@misc{etde_20637404,
title = {The cancerogenicity of fall out nuclides}
author = {Nilsson, Agnar}
abstractNote = {One of the more than 400 radionuclides which are produced in a nuclear reactor only a few of these have features such as solubility, long physical and biological half life and specific affinity to a certain tissue - which could classify them as biologically hazardous. Therefore in this context only radio-iodine-cesium and -strontium are discussed briefly as regards their biological effects. It is pointed out that tumours are not easily induced by radioiodine in experimental systems and that this is also valid for humans. Radiocesium is not very extensively studied experimentally as regards its biological action but available data indicate a low - if any - cancerogenic potentiality in contrast to radiostrontium with its high yield of tumours in various tissues. The extrapolation of experimental data to man as well as a comparison between cancerogenic irradiation doses between man and animals are discussed and considered as a necessity because of the ill defined irradiation situation and data which are connected with most accidental exposure of man. Furthermore it is also pointed out that the general idea that irradiation risks always are represented by a linear dose-effect relationship in most cases has no support from scientific data and therefore give an overestimation of the true risk. This should not be considered as a plea for the abandonment of the 'linear philosophy' but it is necessary to point out that as long as other environmental risks are calculated in a more liberal way, irradiation will always be victimized and discriminated against in the large flora of environmental dangers. The necessity of giving a clear reference to the spontaneous incidence of tumours during the time covered by the calculation must also be presented as well as that the estimate is founded on a hypothesis which is not scientifically proven. (author)}
place = {IAEA}
year = {1986}
month = {Jul}
}